INTRON BIOTECHNOLOGY, INC. Patent applications |
Patent application number | Title | Published |
20160051707 | Metal Oxide Nanoparticle-Based T1-T2 Dual-Mode Magnetic Resonance Imaging Contrast Agent - The present invention relates to a magnetic resonance imaging (MRI) contrast agent, particularly a metal oxide nanoparticle-based T1-T2 dual-mode MRI contrast agent that can be used not only as a T1 MRI contrast agent but also as a T2 MRI contrast agent, and a method for producing the same. The metal oxide nanoparticle-based T1-T2 dual-mode MRI contrast agent can provide more accurate and detailed information associated with disease than single MRI contrast agent by the beneficial contrast effects in both T1 imaging with high tissue resolution and T2 imaging with high feasibility on detection of a lesion. | 02-25-2016 |
20150322409 | METHOD FOR PREVENTION AND TREATMENT OF ESCHERICHIA COLI INFECTIONS USING A BACTERIOPHAGE WITH BROAD ANTIBACTERIAL SPECTRUM AGAINST ESCHERICHIA COLI - The present invention relates to a composition comprising the bacteriophage EK88P-1 isolated from the nature and having a broad antibacterial spectrum against | 11-12-2015 |
20140377842 | BACTERIOPHAGE HAVING BACTERICIDAL ACTIVITY WITH RESPECT TO ACTINOBACILLUS PLEUROPNEUMONIAE - The present invention relates to a bacteriophage having bactericidal activity against | 12-25-2014 |
20140363401 | METHOD FOR PREVENTING AND TREATING SALMONELLA TYPHIMURIUM INFECTION - The present invention relates to a composition comprising STP-1, a bacteriophage isolated from nature, capable of infecting | 12-11-2014 |
20130273635 | BACTERIOPHAGE KILLING PSEUDOMONAS AERUGINOSA AND STAPHYLOCOCCUS AUREUS - The present invention relates to a bacteriophage PA1Φ belonging to family Siphoviridae, characterized that it is capable of killing one or more bacteria strains selected from a group comprising | 10-17-2013 |
20130011369 | Method for Prevention and Treatment of Salmonella Infection - The present invention relates to a composition comprising bacteriophage SP-1, the bacteriophage capable of destroying | 01-10-2013 |
20120230919 | MRI CONTRAST AGENT COATED WITH CARBOXYLATED MANNAN AND METHOD FOR PRODUCING THE SAME - The present invention relates to a magnetic resonance imaging (MRI) contrast agent coated with carboxylated mannan, particularly a carboxylated mannan coated superparamagnetic MRI contrast agent specifically targeting antigen presenting cells and having excellent in vivo stability, and a method for producing the same. The MRI contrast agent coated with carboxylated mannan of the present invention can provide excellent in vivo stability and biocompatibility owing to its high surface negative charge, and can be introduced specifically into antigen presenting cells owing to mannose of mannan, so as to visualize the antigen presenting cells and the tissue containing the antigen presenting cells in MRI. | 09-13-2012 |
20110014714 | METHOD FOR SELECTIVE LABELING OF PROTEIN PRODUCED BY IN VITRO TRANSLATION BY USING A MARKER FROM TRNA PREPARED BY USING IN VITRO TRANSCRIPTION - The present invention relates to a method for the preparation of a labeling material (labeling agent) usable for non-radioactive selective labeling of proteins produced by in vitro translation with fluorophore or biotin; and a method for selective labeling of proteins produced by in vitro translation using the said labeling material. More specifically, the present invention provides a method for preparing a labeling material usable for selective labeling of a target protein produced only from the gene added to the cell-free protein synthesis reaction mixture by an experimenter without labeling pre-existing proteins in the reaction mixture, for which only one type of tRNA prepared by in vitro transcription is used instead of “total tRNA mixture”. The present invention also provides a method for labeling of the protein produced by in vitro translation by using the labeling material prepared by the above method. According to the present invention, the preparation of a labeling material becomes easier and the protein labeled with the labeling material of the present invention provides much improved signals than the protein labeled with the labeling material of the conventional method prepared by using “total tRNA mixture” as a tRNA material. | 01-20-2011 |
20100267117 | Bacteriophage Having Killing Activity Specific to Staphylococcus Aureus - The present invention relates to a novel bacteriophage, more precisely a novel bacteriophage having killing activity specific to | 10-21-2010 |
20100255570 | Polymerase Chain Reaction Product-Cloning Vector Suitable to its Easy Production and Method for Producing the Same - The present invention relates to a PCR product cloning vector applicable directly to the cloning of a PCR product. More precisely, the present invention relates to a PCR product cloning vector designed to be effective in use for blue/white colony selection and produced based on the restriction enzyme treatment process to generate non- complementary unpaired single overhang and a method for producing the same. According to the method of the present invention, the PCR product cloning vector designed to be advantageous for blue/white cloning selection can be produced with improved efficiency compared with the convention method. | 10-07-2010 |
20100203180 | Antimicrobial protein derived from podoviriedae bacteriophage specific to staphylococcus aureus - The present invention relates to a novel antimicrobial protein derived from bacteriophage having killing activity specific to | 08-12-2010 |
20100203019 | Podoviriedae bacteriophage having killing activity specific to staphylococcus aureus - The present invention relates to a novel bacteriophage, more precisely a Podoviridae bacteriophage having killing activity specific to | 08-12-2010 |
20100172918 | NOVEL LYSIN PROTEIN HAVING BROAD ANTIBACTERIAL ACTIVITY SPECIFIC TO BACTERIA - The present invention relates to a lysin protein originated from bacteriophage, more precisely a lysin protein comprising the amino acid sequence represented by SEQ. ID. NO: 2 which has no harm to human and animals comprising eukaryotic cells owing to its specificity to bacteria and has broad antibacterial activity, and a pharmaceutical composition for the prevention and treatment of infectious disease caused by bacteria comprising the said lysin protein as an active ingredient. | 07-08-2010 |
20100144619 | Antimicrobial Protein Specific to Staphylococcus Aureus - The present invention relates to a novel bacteriophage-originated protein having antimicrobial activity, more precisely an antimicrobial protein originated from lytic bacteriophage having killing activity specific to | 06-10-2010 |
20100087306 | Centrifuging device with a detachable cover and a safeguard structure for prevention of the departure of rotor from it - Disclosed is a centrifuging device with a detachable cover and a safeguard structure in which the cover of the centrifuging device can be completely separated from the housing; and the safeguard structure can prevent a rotor from becoming separated from a drive shaft during operation due to flange defection and prevent the fractured pieces of the rotor from springing out of the housing when the rotor breaks or cracks. The centrifuging device according to the invention offers ease of cleaning and improved safety. Furthermore, there is no need to worry about the fracture of a coupling portion between the cover and the housing attributable to the repeated opening and closing. | 04-08-2010 |
20090304638 | Composition for the treatment of ballast water containing bacteriophage as an effective component and biological method with the same for removing bacteria present in ballast water - The present invention relates to a composition for the treatment of ballast water containing bacteriophage capable of killing specific target bacteria as an active ingredient in order to eliminate or reduce bacteria including pathogenic bacteria present in ballast water, and a biological treatment method of ballast water. | 12-10-2009 |
20090258353 | PCR primer capable of reducing non-specific amplification and PCR method using the PCR primer - The present invention relates to a PCR primer facilitating hot-start PCR by suppressing non-specific amplification at room temperature and at the same time capable of reducing significantly non-specific amplification by dominating the amplification of the PCR product rather than the amplification of the original template from the third PCR cycle, more precisely a PCR primer prepared by additionally inserting the reverse-complementary sequence to a certain region starting from the 5′-start site of the 5′-terminus of the original primer which is composed of priming sequence to anneal to a PCR template into the 5′-terminus of the original primer and a PCR method using the same. The primer of the present invention has a original primer sequence composed of priming sequence to anneal to a PCR template and an additional reverse-complementary sequence, which inserted into the 5′-terminus of the original primer, to a certain region starting from the 5′-start site of the 5′-terminus of the original primer sequence, suggesting that a template-specific sequence and its reverse-complementary sequence are included in the same primer. The present invention can improve PCR specificity by reducing non-specific amplification. | 10-15-2009 |
20090220963 | KIT SUITABLE FOR SCREENING AND ESTABLISMENT OF OPTIMAL AMPLIFICATION CONDITION IN PCR CONSTRUCTED WITH DRIED-FORMULATED PCR REAGENT AND METHOD FOR PRODUCING THE SAME - The present invention relates to a kit for screening and establishing optimal amplification condition for individual PCR using a dried-formulated PCR reagent which is composed of different combinations of various components affecting PCR result, to provide a method for screening and establishment of optimal amplification in PCR constructed with a dried-formulated PCR reagent. According to the present invention, researchers can perform PCR under the optimal amplification conditions appropriate for individual PCR even with a PCR-related product constructed from a dried-formulated PCR reagent, suggesting that a unique target gene can be efficiently amplified by PCR constructed with a dried-formulated PCR reagent under the more appropriate conditions. | 09-03-2009 |