Hangzhou Pushai Pharmaceutical Technology Co., LTD. Patent applications |
Patent application number | Title | Published |
20160046615 | Novel Crystal Form of Dabrafenib Mesylate and Preparation Method Thereof - Disclosed are a novel crystal form of Dabrafenib mesylate and preparation method thereof. The novel crystal form of the present invention is more stable in water or an aqueous system, and has greater solubility and dissolution in water, thus having better stability and bioavailability compared with the existing crystal forms. | 02-18-2016 |
20150307484 | Crystal Form of Dabrafenib and Preparation Method and Use Thereof - The invention relates to a new crystal form of dabrafenib and preparation method thereof. With respect to known crystal forms, the new crystal form has the advantage of being more stable at room temperature or in aqueous systems, and has low hygroscopicity, and thus is more suitable for a wet granulation process or being prepared into a suspension. The present invention also relates to a pharmaceutical composition and formulations comprising the new crystal form, and their use in the treatment of Raf family kinase-related diseases. | 10-29-2015 |