Deutsches Krebsforschungszentrum Stiftung des offentlichen Rechts Patent applications |
Patent application number | Title | Published |
20130245461 | Visualization of Anatomical Data by Augmented Reality - A sensor means is employed to sense a distance to the surface of a subject to be examined, so that a range image may be acquired. Intensity information may be acquired alongside the distance information. The distance information and intensity information may be evaluated to track the pose of the sensor means relative to the surface of the subject to be examined, so that anatomical data related to said subject may be displayed as seen from the position and/or orientation of the sensor means or display means. By moving the sensor means or display means along the surface of the subject to be examined, such as a patient in a hospital environment, the user hence gets the impression of being able to look directly into the human body. | 09-19-2013 |
20120258039 | TREATMENT OF TUMORS USING SPECIFIC ANTI-L1 ANTIBODY - The present invention relates to the anti-L1 monoclonal antibody 9.3 as well as to related antibodies or binding molecules and well as to the uses thereof, especially in tumor treatment. | 10-11-2012 |
20120213734 | Method for Cancer Therapy Based on a Co-Administration of a Parvovirus and a Cytokine - Described is a pharmaceutical composition comprising (a) a parvovirus and (b) a cytokine, preferably IFN-γ, and the use of said composition for treatment of cancer, e.g., a brain tumor. | 08-23-2012 |
20120035200 | GRISEOFULVIN ANALOGUES FOR THE TREATMENT OF CANCER BY INHIBITION OF CENTROSOMAL CLUSTERING - The invention relates to compounds of the formula (I), where the symbols have the meaning given in the specification, for use in a method for treating cancer, to use of these compounds for the manufacture of a pharmaceutical composition for the treatment of cancer, and to methods of treatment for said diseases employing a compound of formula (I). | 02-09-2012 |
20110189194 | USE OF CD95 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISORDERS - The present invention refers to the use of an inhibitor of the CD95/CD95L system for the prevention and/or treatment of an inflammatory disorder or for the prevention and/or treatment of an inflammatory process in a neuronal disorder, particularly in a CNS disorder. | 08-04-2011 |
20100305187 | METHODS AND COMPOUNDS FOR TREATING DISEASES CAUSED BY REACTIVE OXYGEN SPECIES - Provided is a method of treating a patient having an inflammatory disease by using a compound which inhibits the complex I-mediated ROS production, a medicament containing such compound and methods for screening for such compounds. | 12-02-2010 |
20100144847 | FUSION POLYPEPTIDE SUITABLE AS A CYTOTOXIN - The present invention relates to fusion polypeptides including (a) a binding site for a cytoskeleton component and (b | 06-10-2010 |
20100076305 | METHOD, SYSTEM AND COMPUTER PROGRAM PRODUCT FOR TARGETING OF A TARGET WITH AN ELONGATE INSTRUMENT - An embodiment is directed to a method and a system for assisting the targeting of a target with an elongate instrument, wherein the instrument is to be inserted into a living object's body part along a predetermined trajectory extending between an entry point of said instrument into said body part and a target point associated with said target. The method comprises an instrument directing assisting step for generating and displaying an image allowing a user to assess to which extend the longitudinal axis of the instrument is aligned with the vector connecting the target point and the tip portion of said instrument. Also, the method comprises an instrument guiding assisting step of generating and displaying an image allowing a user to assess to which extent the instrument motion during insertion thereof coincides with the predetermined trajectory. | 03-25-2010 |
20100029751 | COMPOSITIONS COMPRISING A PARVOVIRUS VP1-VARIANT AND A PARVOVIRUS NS1 PROTEIN FOR INDUCTION OF CYTOLYSIS - The present invention provides a composition comprising (a) a parvovirus NS1 protein and (b) a parvovirus VP1 protein. Furthermore, the present invention provides DNA sequences encoding said proteins. The composition of the invention is useful for the preparation of a toxin for treating tumoral diseases. | 02-04-2010 |
20100016545 | PROCESS FOR THE COVALENT COUPLING OF TWO MOLECULES BY MEANS OF A DIELS-ALDER REACTION WITH INVERSE ELECTRON REQUIREMENT - The present invention relates to a process for linking two molecules by means of a Diels Alder reaction with inverse electron requirement (DARinv), comprising the following steps: reaction of a (a) triazine or tetrazine with one or more electron-attracting substituents on the ring as a diene component, the electron-attracting substituents being selected from:
| 01-21-2010 |
20090280095 | CELL CULTURE OF KERATINOCYTES UNDER NON-DIFFERENTIATING CONDITIONS - The present invention relates to a cell culture medium comprising (a) an inhibitor of bone morphogenetic protein-4 (BMP-4) and (b) an inhibitor of pigment epithelium-derived factor (PEDF, also known as SerpinF1). In one embodiment, the inhibitors are antibodies against BMP-4 and PEDF, respectively. The medium allows to culture keratinocytes under non-differentiating conditions. The invention also relates to corresponding methods and kits. As the media and methods disclosed allow for an improved manufacture of keratinocytes, the invention also relates to the treatment of skin wounds and to the manufacture of corresponding medicaments. This will be of advantage for treatment e.g. of burns, ulcers, etc., in which transplantation of keratinocytes or skin is required. | 11-12-2009 |
20090221040 | ANTIBODIES ACTIVE AGAINST A FUSION POLYPEPTIDE COMPRISING A HISTIDINE PORTION - The present invention relates to an antibody active against a fusion polypeptide comprising a histidine portion, a process for the preparation thereof and its use. | 09-03-2009 |
20090137502 | Riproximin, a Novel Type II Ribosome-Inactivating Protein and Uses Thereof - Described is a novel type II ribosome-inactivating protein, riproximin, as well as nucleic acid molecules encoding said protein. Furthermore, therapeutic uses of riproximin are described. | 05-28-2009 |
20090060130 | Inverse Treatment Planning Method - The invention relates to a radiation treatment apparatus and an inverse treatment planning method for intensity modulated particle therapy for the treatment of a target within a biological system using at least two fields, each field comprising a plurality of Bragg peaks, the at least two fields being planned to place a defined number of beam spots j from different directions with certain weights w | 03-05-2009 |
20090039268 | Dual-modality imaging - The invention relates to a dual-modality imaging system and a method for dual-modality imaging, wherein a positron emission tomography (PET) scanner for acquiring PET imaging data and at least one optical imaging detector for acquiring optical imaging data are arranged to acquire the PET imaging data and the optical imaging data of an imaged object ( | 02-12-2009 |
20090032714 | Optical imaging detector - The invention relates to an optical imaging detector for fluorescence and bioluminescence imaging of an imaged object that can be used for tomographic imaging. The optical imaging detector comprises at least one micro-lens array with a plurality of micro-lenses. A photo detector can be located either in the focal plane of the micro-lens array or can be connected to the micro-lens array by a network of optical fibres and be located externally. | 02-05-2009 |