20160137825 | A PART CONSISTING OF A MATERIAL AND A METHOD OF MANUFACTURING SUCH PART AND A METHOD OF RADIATION STERILIZATION OF SUCH PART - The material of a part includes a composition obtained by blending an isobutylene-based, pre-crosslinked polymer as component (A), at least one poly olefin or a non-crosslinked rubber or a TPV as component (B), at least one polymer having a Tg of 90° C. or higher as component (C) and—preferably—at least one component (D) selected from the group of: substituted vinyl polymers, stryrenic block copolymers, inorganic functionalized and non-functionalized fillers, carbon black, halogen scavengers, preferably the inorganic halogen scavengers, acid acceptors, stabilizers, preferably the polymeric stabilizers, and processing aids. Also, a method of manufacturing such part includes the steps: a) Pre-mixing at least one substance representing component B, with at least one substance representing component C and at least one substance representing component D; b) compounding the obtained premix with component A and optionally a further portion of component B or D; and c) molding the resulting composition of step (b) into a pharmaceutical seal. Also, a method of radiation sterilization a part, e.g. a pharmaceutical closure, the part being produced from compounds based on thermoplastic vulcanizates including isobutylene monomer units, prior to irradiation, packs the parts under an inert atmosphere in a container impermeable to oxygen, wherein the packed closure materials are irradiated for sterilization. | 05-19-2016 |
20150298414 | METHOD FOR PRODUCING A FLANGED CAP, AND A FLANGED CAP - A method produces a flanged cap and a flanged cap for a vessel accommodates a pharmaceutical substance, particularly a vial, wherein the flanged cap is formed from one material strip (M) having a film layer that has already been plastic-coated, wherein the material strip is thereafter stamped out and shaped via deep-drawing. A plastic component is affixed on the plastic coating of the flanged cap that forms a plastic layer. A flanged cap for a vessel for accommodating a pharmaceutical substance, particularly a vial, is formed from a metal film layer, wherein the film layer is likewise covered on the outside with a plastic layer that forms a coating on the film layer. A vessel contains a pharmaceutical substance. | 10-22-2015 |