DANISCO US INC. Patent applications |
Patent application number | Title | Published |
20160130571 | Alpha-Amylase from Bacillaceae Family Member - Disclosed are compositions and methods relating to an alpha-amylase from a Bacillaceae family member. The compositions and methods are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing. | 05-12-2016 |
20160122735 | VARIANTS OF CELLOBIOHYDROLASES - Disclosed are a number of homologs and variants of | 05-05-2016 |
20160122734 | VARIANTS OF CELLOBIOHYDROLASES - Disclosed are a number of homologs and variants of | 05-05-2016 |
20160115465 | COMPOSITIONS AND METHODS OF USE - The present compositions and methods relate to a beta-mannanase from | 04-28-2016 |
20160068879 | TRICHODERMA REESEI GLUCOAMYLASE VARIANTS RESISTANT TO OXIDATION-RELATED ACTIVITY LOSS AND THE USE THEREOF - Embodiments of the present disclosure relate to | 03-10-2016 |
20160060665 | HEMICELLULASE ENRICHED COMPOSITIONS FOR ENHANCING HYDROLYSIS OF BIOMASS - Described are compositions and methods relating to cellulase/hemicellulase enzyme blends for improving the enzymatic hydrolysis of cellulosic and hemicellulosic materials, as commonly found in biomass. | 03-03-2016 |
20160060611 | COMPOSITIONS AND METHODS COMPRISING THERMOLYSIN PROTEASE VARIANTS - The present invention provides serine protease—thermoslysine—variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants. | 03-03-2016 |
20160040147 | Proteases With Modified Pro Regions - The present invention provides methods and compositions for the production of mature proteases in bacterial host cells. The compositions include modified polynucleotides that encode modified proteases, which have at least one mutation in the pro region; the modified serine proteases encoded by the modified polynucleotides; expression cassettes, DNA constructs, and vectors comprising the modified polynucleotides that encode the modified proteases; and the bacterial host cells transformed with the vectors of the invention. The methods include methods for enhancing the production of mature proteases in bacterial host cells e.g. | 02-11-2016 |
20160040144 | Thermostable Trichoderma Cellulase - Described are compositions and methods relating to the thermostable fungal cellulase enzyme, EGV, and | 02-11-2016 |
20160032267 | METHODS FOR IMPROVING MULTIPLE PROTEIN PROPERTIES - The present invention provides efficient methods for obtaining a protein with one or more beneficial attributes in industrial, consumer or pharmaceutical applications. In some preferred embodiments, the present invention provides methods for producing superior enzymes for a given application through screening an abbreviated set of candidate enzymes. | 02-04-2016 |
20160017305 | ALPHA-AMYLASE COMBINATORIAL VARIANTS - Disclosed are compositions and methods relating to variant alpha-amylases. The variant alpha-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing. | 01-21-2016 |
20160017304 | ALPHA-AMYLASE COMBINATORIAL VARIANTS - Disclosed are compositions and methods relating to variant alpha-amylases. The variant alpha-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing. | 01-21-2016 |
20160017303 | ALPHA-AMYLASE COMBINATORIAL VARIANTS - Disclosed are compositions and methods relating to variant alpha-amylases. The variant alpha-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing. | 01-21-2016 |
20150344923 | COMPOSITIONS AND METHODS OF USE - The present compositions and methods relate to a beta-mannanase from | 12-03-2015 |
20150344922 | COMPOSITIONS AND METHODS OF USE - The present compositions and methods relate to a beta-mannanase from | 12-03-2015 |
20150344858 | NOVEL MANNANASE, COMPOSITIONS AND METHODS OF USE THEREOF - The present compositions and methods relate to an endo-beta-mannanase cloned from | 12-03-2015 |
20150329842 | COMPOSITIONS AND METHODS COMPRISING CELLULASE VARIANTS WITH REDUCED AFFINITY TO NON-CELLULOSIC MATERIALS - The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having reduced binding to non-cellulosic materials. Also described are nucleic acids encoding the cellulase, compositions comprising said cellulase, methods of identifying cellulose variants and methods of using the compositions. | 11-19-2015 |
20150320081 | MELT-DELAYED GRANULE - The present teachings provide an improved layered granule comprising a melt-delayed layer located internal to a melt-resistant layer. The melt-delayed granules can be used in a variety of contexts, including animal feed. Methods of making and using the melt-delayed granules are also provided. | 11-12-2015 |
20150315560 | VARIANTS OF CELLOBIOHYDROLASES - Disclosed are a number of homologs and variants of | 11-05-2015 |
20150299683 | EGVII Endoglucanase and Nucleic Acids Encoding the Same - The present invention provides a novel endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVII proteins and methods for producing the same. | 10-22-2015 |
20150291944 | COMPOSITIONS AND METHODS COMPRISING A LIPOLYTIC ENZYME VARIANT - The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having one or more modifications as compared to a parent lipolytic enzyme having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention. | 10-15-2015 |
20150284756 | EXPRESSION OF GRANULAR STARCH HYDROLYZING ENZYMES IN TRICHODERMA AND PROCESS FOR PRODUCING GLUCOSE FROM GRANULAR STARCH SUSTRATES - The present invention relates to filamentous fungal host cells and particularly | 10-08-2015 |
20150284700 | BGL7 Beta-Glucosidase and Nucleic Acids Encoding the Same - The present invention provides a novel β-glucosidase nucleic acid sequence, designated bgl7, and the corresponding BGL7 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL7, recombinant BGL7 proteins and methods for producing the same. | 10-08-2015 |
20150275255 | Endoglucanase For Reducing The Viscosity Of A Plant Materials Slurry - The present disclosure relates to composition comprising EG cellulase and methods of use, thereof. The compositions are useful, e.g., for reducing the viscosity of plant material slurry. | 10-01-2015 |
20150252344 | BETA-GLUCOSIDASE FROM NEUROSPORA CRASSA - The present compositions and methods relate to a beta-glucosidase from | 09-10-2015 |
20150252343 | BETA-GLUCOSIDASE FROM MAGNAPORTHE GRISEA - The present compositions and methods relate to a beta-glucosidase from | 09-10-2015 |
20150252340 | COMPOSITIONS AND METHODS OF US - The present compositions and methods relate to a beta-glucosidase from | 09-10-2015 |
20150247140 | Compositions and Methods Comprising Variant Microbial Proteases - The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant proteases suitable for laundry cleaning applications. | 09-03-2015 |
20150240192 | COMPOSITIONS AND METHODS COMPRISING A SUBTILISIN VARIANT - The present invention provides a | 08-27-2015 |
20150232829 | Multiply-Substituted Protease Variants - Novel protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occurring or recombinant protease to generate the substitution of a plurality of amino acid residues in the amino acid sequence of a precursor protease. Such variant proteases have properties which are different from those of the precursor protease, such as altered wash performance. The substituted amino acid residue equivalent to positions 7, 23, 26, 28, 29, 30, 31, 47, 66, 69, 73, 82, 85, 88, 90, 92, 93, 105, 113, 139, 148, 149, 150, 151, 178, 200, 201, 231, 233, 267 and/or 273 of | 08-20-2015 |
20150218492 | ENZYME FABRIC CARE TABLETS FOR CONSUMERS AND METHODS - Single-dose enzyme tablets for direct sale to consumers are provided for boosting the performance of automatic laundry and dish washing operations using conventional detergents. The tablets provide a wash performance that is better than or at least equal to the wash performance of the detergents alone even when the time and or temperature of the wash cycle is decreased. The tablets may be provided in kits and the enzymes are selected to treat a variety of fabric stains as well as to provide fabric care benefits. | 08-06-2015 |
20150216207 | ENZYME GRANULE BLENDS CONSISTING ESSENTIALLY OF SODIUM SULFATE - The present teachings provide ways of improving the distribution of high payload enzyme granules by reducing their size, and by mixing them with size-matched dummy particles containing sodium sulfate. The present teachings also provide methods of using the mixtures. | 08-06-2015 |
20150203620 | POLYMERS OF ISROPENE FROM RENEWABLE RESOURCES - It has been found that certain cells in culture can convert more than about 0.002 percent of the carbon available in the cell culture medium into isoprene. These cells have a heterologous nucleic acid that (i) encodes an isoprene synthase polypeptide and (ii) is operably linked to a promoter. The isoprene produced in such a cultured medium can then be recovered and polymerized into synthetic rubbers and other useful polymeric materials. The synthetic isoprene containing polymers of this invention offer the benefit of being verifiable as to being derived from non-petrochemical based resources. They can also be analytically distinguished from rubbers that come from natural sources. The present invention more specifically discloses a polyisoprene polymer which is comprised of repeat units that are derived from isoprene monomer, wherein the polyisoprene polymer has δ | 07-23-2015 |
20150159147 | Compositions And Methods Comprising Variant Microbial Proteases - The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant subtilisins suitable for laundry cleaning applications. | 06-11-2015 |
20150152458 | LOW TEMPERATURE METHOD FOR MAKING HIGH GLUCOSE SYRUP - The present teachings provide a method for making a high glucose syrup at a low temperature. In some embodiments, the syrup contains reduced reversion reaction products. The method comprises contacting a starch substrate at a temperature below the starch gelatinization temperature with an enzyme blend comprising a high dose of alpha-amylase and a low dose of glucoamylase. In some embodiments, a blend of two glucoamylases is employed. In some embodiments, a debranching enzyme such as a pullulanase is employed. In some embodiments, the enzymes are staged by adding at different times, or at different temperatures. The present teachings provide for high glucose syrups with fewer reversion products, and allow for higher starch solubilization. | 06-04-2015 |
20150152457 | DIRECT STARCH TO FERMENTABLE SUGAR - Provided herein are compositions and methods related to the direct conversion of the starch in a ground or fractionated grain into a fermentable sugar feedstock capable of serving as a carbon source for the industrial production of one or more products by a fermenting organism. Such conversions may be performed at temperatures at or below the initial gelatinization temperature of the starch present in the grain and may utilize one or more isolatable endogenous enzymes present in certain unrefined grains. | 06-04-2015 |
20150152401 | ALPHA AMYLASE VARIANTS DERIVED FROM THE ALPHA AMYLASE OF CYTOPHAGA SP. AMYLASE (CSPAMY2) - Disclosed are compositions and methods relating to variant alpha-amylases. The variant alpha-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing. | 06-04-2015 |
20150147768 | Microtiter plates for controlled release of culture components to cell cultures - The invention provides a culture plate made from a polymer incorporating a culture component releasable into culture media in the well, methods of culturing a microorganisms in the culture plate, and a methods of making the culture plate. | 05-28-2015 |
20150141316 | VARIANT ALPHA AMYLASES WITH ENHANCED ACTIVITY ON STARCH POLYMERS - Described are variants of alpha-amylase enzymes for use in industrial processes, such as liquefaction of starch. The alpha-amylase variants have increased specific activity allowing the more rapidly reduction of peak viscosity during liquefaction processes. The alpha-amylase is modified by introducing into the amino sequence of a parent Family 13 alpha-amylase polypeptide a mutation at an amino acid residue in the starch-binding groove; wherein the starch-binding groove is formed by amino acid residues in the alpha-helix preceding the first beta-strand in the A domain, the loop between the sixth alpha-helix and the seventh beta-strand in the A domain, the loop between the seventh alpha-helix and the eighth beta-strand in the A domain, and the loop connecting the A domain and the C domain; and wherein the mutation alters the binding of starch to the variant alpha amylase polypeptide compared to the parental alpha amylase polypeptide. | 05-21-2015 |
20150140613 | ENHANCED FERMENTATION PROCESS USING MOLASSES - Described herein are compositions and methods for enhanced fermentation of molasses using transglucosidase. | 05-21-2015 |
20150140172 | SANDWICH GRANULE - The present teachings provide an improved layered granule comprising a sandwich structure of a first and second moisture barrier layer encompassing a moisture hydrating layer. The sandwich granules can be used in a variety of contexts, including animal feed. Methods of making and using are also provided. | 05-21-2015 |
20150132825 | COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS - The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants. | 05-14-2015 |
20150132800 | Trichoderma Hydrophobin Production - The invention relates to a method for maximizing expression of a biosurfactant, such as hydrophobin, in a microorganism, in particular a | 05-14-2015 |
20150118211 | Enzymatic Prevention and Control of Biofilm - The invention provides methods, compositions, and kits for removal of biofilms from surfaces. The methods described herein comprise simultaneous or sequential application of a perhydrolase enzyme and a mixture of other enzymes, such as proteases, glucanases, esterases, mannanases, phospholipases, cellulases, and/or amylases, to a biofilm on a surface, to effect removal of the biofilm. | 04-30-2015 |
20150111281 | Production of Porphyrin-Containing Polypeptides in the Presence of Formate - The present compositions and methods relate to the production of polypeptides in submerged culture, and specifically the large-scale production of porphyrin-containing polypeptides, e.g. catalase, by microbial fermentation in the presence of formate. | 04-23-2015 |
20150111259 | Method for Making High Maltose Syrup - The present teachings provide direct conversion of granular starch into a soluble sugar composition comprising a high, very high, and/or ultra high maltose content. The method involves contacting an aqueous slurry of granular starch with an enzyme composition comprising an appropriate ratio of an alpha-amylase and a maltogenic enzyme to produce a soluble starch substrate that is enzymatically converted to a sugar composition containing higher maltose. The process may use more than one temperature to achieve the same. | 04-23-2015 |
20150093805 | POLYPEPTIDES HAVING ALPHA-AMYLASE AND GRANULAR STARCH HYDROLYZING ACTIVITY - The present invention relates to a polypeptide having alpha-amylase activity obtained from a strain of | 04-02-2015 |
20150087573 | Compositions and Methods Comprising Alpha-Amylase Variants with Altered Properties - Described are compositions and methods relating to variant alpha-amylasess having altered biochemical properties and advantageous performance characteristics as compared to a reference alpha-amylase. The variants are suitable for use in various industrial applications such as starch conversion, ethanol production, laundry, dishwashing, pulp and paper production, textile desizing, and/or sweetener production. | 03-26-2015 |
20150079638 | VARIANT HUMICOLA GRISEA CBH1.1 - Disclosed are variants of | 03-19-2015 |
20150072913 | Multiple Mutation Variants of Serine Protease - The present invention provides novel Micrococcineae spp serine proteases having multiple substitutions. In particular, the present invention provides serine proteases having multiple substitutions, DNA encoding these proteases, vectors comprising the DNA encoding the proteases, host cells transformed with the vector DNA, and enzymes produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising these serine protease variants. In particularly preferred embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These variant proteases also find use in numerous applications. | 03-12-2015 |
20150072380 | COMPOSITIONS AND METHODS FOR IMPROVED PROTEIN PRODUCTION - The present invention relates to the identification of novel nucleic acid sequences, designated herein as 7p, 8k, 7E, 9G, 8Q and 203, in a host cell which effect protein production. The present invention also provides host cells having a mutation or deletion of part or all of the gene encoding 7p, 8k, 7E, 9G, 8Q and 203, which are presented in FIG. | 03-12-2015 |
20150065412 | PROTEASES COMPRISING ONE OR MORE COMBINABLE MUTATIONS - The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided. | 03-05-2015 |
20150064767 | COMPOSITIONS AND METHODS COMPRISING VARIANT MICROBIAL PROTEASES - The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant subtilisins suitable for laundry cleaning applications. | 03-05-2015 |
20150064736 | NOVEL 2,5-DIKETO-L-GLUCONIC ACID REDUCTASES AND METHODS OF USE - Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described. | 03-05-2015 |
20150057434 | METHODS OF PURIFYING HYDROPHOBIN - The invention relates to a recovery and/or purification process of hydrophobins involving organic solvents and does not require separation techniques. In particular, the invention relates to a method for selective alcohol precipitation of hydrophobin II. | 02-26-2015 |
20150056682 | Compositions and Methods Comprising Variant Microbial Proteases - The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant proteases suitable for laundry cleaning applications. | 02-26-2015 |
20150044736 | FUNGAL CUTINASE FROM MAGNAPORTHE GRISEA - Described are compositions and methods relating to a fungal cutinase cloned from | 02-12-2015 |
20150031589 | COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS - The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants. | 01-29-2015 |
20150031109 | POLYOL OXIDASES - The present invention provides compositions and methods for producing a polyol oxidase in micoroorganisms, and the use of polyol oxidases in cleaning compositions. The invention includes cleaning compositions that contain combinations of two or more POx oxidases, and cleaning compositions that contain combinations of two or more POx oxidases and a perhydrolase. In particular, the invention provides methods for expressing polyol oxidases in bacterial hosts for use in detergent applications for cleaning, bleaching and disinfecting. | 01-29-2015 |
20150030679 | STABLE, DURABLE GRANULES WITH ACTIVE AGENTS - A stable, durable granule for feed compositions has a core, at least one active agent; and at least one coating. The active agent of the granule retains at least 50% activity, at least 60% activity, at least 70% activity, at least 80% activity after conditions selected from one or more of a) a feed pelleting process, b) a steam-heated feed pretreatment process, c) storage, d) storage as an ingredient in an unpelleted mixture, and e) storage as an ingredient in a feed base mix or a feed premix comprising at least one compound selected from trace minerals, organic acids, reducing sugars, vitamins, choline chloride, and compounds which result in an acidic or a basic feed base mix or feed premix. | 01-29-2015 |
20150017701 | HYBRID ALPHA-AMYLASES - Hybrid alpha-amylases are provided that share a conserved 3D structure in whole or in part with a wild-type Termamyl-like α-amylase, e.g., a | 01-15-2015 |
20150011743 | METHOD TO IMPROVE THE STABILITY AND BROADEN THE PH RANGE OF FAMILY G/11 XYLANASES - The present invention relates to protein engineering, and concerns especially family G/11 xylanases, and genes encoding said enzymes. In specific, the invention concerns | 01-08-2015 |
20150010970 | METHODS FOR PRODUCING END-PRODUCTS FROM CARBON SUBSTRATES - The present invention provides means for the production of desired end-products of in vitro and/or in vivo bioconversion of biomass-based feed stock substrates, including but not limited to such materials as starch and cellulose. In particularly preferred embodiments, the methods of the present invention do not require gelatinization and/or liquefaction of the substrate. | 01-08-2015 |
20140377841 | Detergent Compositions Containing Bacillus Agaradhaerens Mannanase and Methods of Use Thereof - The present compositions and methods relate to an endo-β-mannanase cloned from | 12-25-2014 |
20140377804 | Filamentous Fungi Having Reduced UDP-Galactofuranose Content - A filamentous fungal cell having reduced UDP-galactofuranose is provided. The fungal cell may, in certain embodiments, contain a nuclear genome comprising an inactivated UDP-galactopyranose mutase (UDP-galp mutase) gene and a recombinant nucleic acid for expression of a protein. Also provided are methods of producing a protein using the subject fungal cell, as well as methods of producing the subject fungal cell. | 12-25-2014 |
20140342930 | METHODS FOR SELECTIVE TARGETING - A selective targeting method is disclosed comprising contacting a library of ligands, particularly a peptide library, with an anti-target to allow the ligands to bind to the anti-target; separating the non-binding ligands from the anti-target bound ligands, contacting the non-binding anti-target ligands with a target allowing the unbound ligands to bind with the target to form a target-bound ligand complex; separating the target-bound ligand complex from ligands which do not bind to the target, and identifying the target-bound ligands on the target-bound ligand complex wherein the target-bound ligands have a K | 11-20-2014 |
20140342432 | Fungal Gene Expression Using Insulator DNA Sequences - Described are compositions and methods relating to the expression of genes of interest in fungal cells using insulator DNA sequences. | 11-20-2014 |
20140342431 | Variant Alpha-Amylases and Methods of Use, Thereof - Compositions and methods relating to variant alpha-amylases are described. | 11-20-2014 |
20140335591 | INCREASED PRODUCTION OF SECRETED PROTEINS BY RECOMBINANT EUKARYOTIC CELLS - Described herein are methods for increasing the amount of protein secreted by a cell. In one case, a cell is provided which contains a heterologous nucleic acid encoding a protein having unfolded protein response modulating activity and a heterologous nucleic acid encoding a protein of interest to be secreted. In one case, the protein having unfolded protein response modulating activity is selected from the proteins selected from the group consisting of HAC1, PTC2 and IRE1. The protein of interest can be any secreted protein such as a therapeutic or an industrial enzyme. For example the protein can be selected from the group consisting of lipase, cellulase, endo-glucosidase H, protease, carbohydrase, reductase, oxidase, isomerase, transferase, kinase, phosphatase, alpha-amylase, glucoamylase, lignocellulose hemicellulase, pectinase and ligninase. | 11-13-2014 |
20140335576 | METHODS FOR INCREASING MICROBIAL PRODUCTION OF ISOPRENE, ISOPRENOIDS, AND ISOPRENOID PRECURSOR MOLECULES USING GLUCOSE AND ACETATE CO-METABOLISM - Provided herein are methods for the increased production of intracellular acetyl-CoA, mevalonate, isoprenoid precursors, isoprene and/or isoprenoids by recombinant microorganisms via co-metabolism of substrates with varied oxidation levels. | 11-13-2014 |
20140315775 | USE AND PRODUCTION OF CITRATE-STABLE NEUTRAL METALLOPROTEASES - The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved stability in the presence of a metal chelator. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications comprising citrate. In some particularly preferred embodiments, the present invention provides methods and compositions comprising variant neutral metalloprotease(s) engineered to resist citrate-induced autolysis. | 10-23-2014 |
20140315313 | FILAMENTOUS FUNGI HAVING AN ALTERED VISCOSITY PHENOTYPE - Described are compositions and methods relating to variant filamentous fungi having altered growth characteristics. Such variants are well-suited for growth in submerged cultures, e.g., for the large-scale production of enzymes and other proteins for commercial applications. | 10-23-2014 |
20140315275 | ISOPRENE SYNTHASE VARIANTS WITH IMPROVED SOLUBILITY FOR PRODUCTION OF ISOPRENE - The present invention provides methods and compositions of variant polypeptides having isoprene synthase activity with improved solubility. In particular, the present invention provides isoprene synthase variant for increased isoprene production in recombinant host cells. | 10-23-2014 |
20140315272 | NOVEL LIPOLYTIC ENZYME LIP2 - The present invention provides a novel nucleic acid sequence, designated LIP2, encoding a lipolytic enzyme and the corresponding encoded amino acid sequences. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding at least one novel lipolytic enzyme, recombinant lipolytic enzyme proteins and methods for producing the same. | 10-23-2014 |
20140308736 | PROTEASES COMPRISING ONE OR MORE COMBINABLE MUTATIONS - The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided. | 10-16-2014 |
20140302590 | Protease Variants Active over a Broad Temperature Range - The present invention provides protease compositions particularly suited for dishwashing applications. | 10-09-2014 |
20140302585 | CELLULASE VARIANTS WITH IMPROVED EXPRESSION, ACTIVITY AND STABILITY, AND USE THEREOF - The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof. | 10-09-2014 |
20140302584 | NOVEL VARIANT HYPOCREA JECORINA CBH1 CELLULASE - Described herein are variants of | 10-09-2014 |
20140302003 | Perhydrolase - The present invention provides methods and compositions comprising at least one perhydrolase enzyme for cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions for generation of peracids. The present invention finds particular use in applications involving cleaning, bleaching and disinfecting. | 10-09-2014 |
20140299532 | FILTRATION WITH INTERNAL FOULING CONTROL - Filtration processes and systems are provided for the separation of a filterable fluid stream by a filtration membrane module with uniform transmembrane pressure and flux along the membrane and internal control of membrane fouling via intermittent periodic reduction of the pressure differential between the permeate and retentate sides of the membrane and/or backwashing cycles during separation, recovery, and/or purification of proteins, peptides, nucleic acids, biologically produced polymers and other compounds or materials from aqueous fluids. | 10-09-2014 |
20140295527 | COMPOSITIONS AND METHODS COMPRISING A SUBTILISIN VARIANT - The present invention provides a | 10-02-2014 |
20140295526 | MODIFIED PROTEASES - This invention relates to modified polynucleotides encoding modified proteases, and methods for altering the production of proteases in microorganisms. In particular, the present invention relates to methods for altering the expression of proteases in microorganisms, such as | 10-02-2014 |
20140295475 | ENZYME COCKTAILS PREPARED FROM MIXED CULTURES - The application provides methods of producing a mixture of enzymes using two or more cell lines, methods of identifying or constructing cell lines for producing a mixture of enzymes, and methods of preparing a cell bank for producing a mixture of enzymes. | 10-02-2014 |
20140294881 | PROTEASES PRODUCING AN ALTERED IMMUNOLOGICAL RESPONSE AND METHODS OF MAKING AND USING THE SAME - The present invention provides novel protein variants that exhibit reduced immunogenic responses, as compared to the parental proteins. The present invention further provides DNA molecules that encode novel variants, host cells comprising DNA encoding novel variants, as well as methods for making proteins less allergenic. In addition, the present invention provides various compositions that comprise these proteins that are less immunogenic than the wild-type proteins. | 10-02-2014 |
20140287477 | Variant Maltohexaose-Forming Alpha-Amylase Variants - Disclosed are compositions and methods relating to variant maltohexaose-forming alpha-amylases. The variant alpha-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing. | 09-25-2014 |
20140287473 | METHODS AND COMPOSITIONS FOR ENHANCED PRODUCTION OF ORGANIC SUBSTANCES FROM FERMENTING MICROORGANISMS - The present invention relates methods and compositions for producing an organic substance from fermenting microorganism using simultaneous saccharification and fermentation. One aspect of the invention provides producing alcohol by simultaneous saccharification and fermentation by combining a cellulosic substrate, and whole fermentation broth, and an ethanologenic microorganism under conditions conducive both to hydrolysis of cellulose to glucose and to conversion of glucose to alcohol. | 09-25-2014 |
20140287462 | GENE INACTIVATED MUTANTS WITH ALTERED PROTEIN PRODUCTION - A recombinant filamentous fungal cell (e.g. | 09-25-2014 |
20140273177 | Compositions and Methods Comprising Protease Variants - The present invention provides protease variants, compositions comprising protease variants, and methods of using such protease variants and compositions. | 09-18-2014 |
20140273145 | PRODUCTION OF ISOPRENE UNDER NEUTRAL pH CONDITIONS - Embodiments of the present disclosure relate to a process for producing isoprene from a starch substrate by saccharification and/or fermentation. The saccharification is effectively catalyzed by a glucoamylase at a pH in the range of 5.0 to 8.0. At a pH of 6.0 or above, the glucoamylase possesses at least 50% activity relative to its maximum activity. The saccharification and fermentation may be performed as a simultaneous saccharification and fermentation (SSF) process. | 09-18-2014 |
20140273134 | Barley-Based Biorefinery Process - The barley-based biorefinery process comprises a method of optimizing the production of ethanol and value-added products from barley feedstock. Specifically, the biorefinery process is an integrated barley treatment process that utilizes essentially all components of barley (including the barley hulls) to efficiently produce ethanol and other value-added liquids and solids. | 09-18-2014 |
20140259452 | ENZYMATIC TEXTILE BLEACHING COMPOSITIONS AND METHODS OF USE THEREOF - Described are compositions and methods for enzymatic bleaching of textiles. A perhydrolase enzyme is used in combination with an ester substrate and hydrogen peroxide to produce a peracid for textile bleaching. Textiles bleached by the exhibit increased dye uptake, decreased textile damage, and/or bulkier softer handle than textiles bleached by conventional chemical bleaching processes. | 09-18-2014 |
20140234933 | EGVII Endoglucanase and Nucleic Acids Encoding the Same - The present invention provides a novel endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVII proteins and methods for producing the same. | 08-21-2014 |
20140234932 | BGL7 Beta-Glucosidase and Nucleic Acids Encoding the Same - The present invention provides a novel β-glucosidase nucleic acid sequence, designated bgl7, and the corresponding BGL7 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL7, recombinant BGL7 proteins and methods for producing the same. | 08-21-2014 |
20140234931 | BGL6 Beta-Glucosidase and Nucleic Acids Encoding the Same - The present invention provides a novel β-glucosidase nucleic acid sequence, designated bgl6, and the corresponding BGL6 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL6, recombinant BGL6 proteins and methods for producing the same. | 08-21-2014 |
20140234926 | RECOMBINANT ANAEROBIC ACETOGENIC BACTERIA FOR PRODUCTION OF ISOPRENE AND/OR INDUSTRIAL BIO-PRODUCTS USING SYNTHESIS GAS - This invention provides for recombinant anaerobic acetogenic bacterial cells having one or more nucleic acids whereby isoprene, mevalonate and/or other industrial bio-products are produced in a substantially oxygen-free culture condition using synthesis gas as energy and/or carbon source. | 08-21-2014 |
20140234490 | BUTTIAUXELLA SP. PHYTASE VARIANTS - Provided herein are variants of | 08-21-2014 |
20140234231 | ALPHA-GLUCANASE AND ORAL CARE COMPOSITION CONTAINING THE SAME - Isolated α-glucanases from | 08-21-2014 |
20140220689 | FILAMENTOUS FUNGI HAVING AN ALTERED VISCOSITY PHENOTYPE - Described are compositions and methods relating to variant filamentous fungi having altered growth characteristics. Such variants are well-suited for growth in submerged cultures, e.g., for the large-scale production of enzymes and other proteins for commercial applications. | 08-07-2014 |
20140212885 | ENDOGENOUS DNASE ACTIVITY TO REDUCE DNA CONTENT - The application provides a method of reducing the DNA content of a protein preparation or a culture broth from a filamentous fungal host cell using an endogenous filamentous fungal host DNase activity. | 07-31-2014 |
20140193886 | SURFACTANTS THAT IMPROVE THE CLEANING OF LIPID-BASED STAINS TREATED WITH LIPASES - Described are compositions and methods relating to the removal of oily stains from fabrics and other surfaces using a lipase in combination with a selected surfactant to mediate the release of fatty acids generated by the lipase. The compositions and methods have application in, e.g., laundry cleaning and dishwashing. | 07-10-2014 |
20140187839 | PURIFICATION OF ISOPRENE FROM RENEWABLE RESOURCES - Methods and apparatus for the purification of isoprene, such as the purification of a bioisoprene composition from fermentor off-gas. The apparatus includes two columns that process the fermentor off-gas, which includes isoprene and various impurities. A solvent is added to the off-gas in the first column, and the isoprene is stripped from the solvent in the second column. Also provided is a downstream further purification process. Also provided are the resulting purified isoprene compositions. | 07-03-2014 |
20140187468 | Compositions and Methods Comprising a Lipolytic Enzyme Variant - The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having one or more modifications as compared to a parent lipolytic enzyme having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention. | 07-03-2014 |
20140187440 | SYSTEMATIC EVALUATION OF SEQUENCE AND ACTIVITY RELATIONSHIPS USING SITE EVALUATION LIBRARIES FOR ENGINEERING MULTIPLE PROPERTIES - The present invention provides methods for protein engineering. Specifically, the invention provides methods utilizing site evaluation libraries to design libraries that optimize two or more properties of a protein. | 07-03-2014 |
20140186922 | PROTEASES PRODUCING AN ALTERED IMMUNOGENIC RESPONSE AND METHODS OF MAKING AND USING THE SAME - The present invention provides novel protein variants that exhibit reduced immunogenic responses, as compared to the parental proteins. The present invention further provides DNA molecules that encode novel variants, host cells comprising DNA encoding novel variants, as well as methods for making proteins less allergenic. In addition, the present invention provides various compositions that comprise these proteins that are less immunogenic than the wild-type proteins. | 07-03-2014 |
20140179007 | EXPRESSION OF GRANULAR STARCH HYDROLYZING ENZYME IN TRICHODERMA - The present invention relates to filamentous fungal host cells and particularly | 06-26-2014 |
20140178945 | PROCESS FOR CONVERSION OF GRANULAR STARCH TO ETHANOL - The present invention concerns a method of producing glucose from a granular starch substrate comprising, contacting a slurry comprising granular starch obtained from plant material with an alpha-amylase at a temperature below the starch gelatinization temperature of the granular starch to produce oligosaccharides and hydrolyzing the oligosaccharides to produce a mash comprising at least 20% glucose and further comprising fermenting the mash to obtain ethanol. | 06-26-2014 |
20140170718 | MULTIMERIC OXIDOREDUCTASES - The present invention concerns multimeric oxidoreductase complexes which function in the enzymatic conversion of a carbon substrate, said complexes having a dehydrogenase subunit and a cytochrome C subunit. The invention further relates to polynucleotides coding for the multimeric complexes and methods of use thereof. | 06-19-2014 |
20140166555 | TANGENTIAL FLOW FILTRATION APPARATUSES, SYSTEMS, AND PROCESSES FOR THE SEPARATION OF COMPOUNDS - The invention relates to apparatuses, machines, systems and methods for the recovery and purification of proteins, peptides, nucleic acids, biologically produced polymers and other compounds from aqueous fluids. The aqueous fluids can comprise enzyme concentrates and or a fermentation broth with or without cells or other starting material. The fermentation broth can be produced by fermentations of fungal, yeast, bacterial, mammalian, insect or plant cells. | 06-19-2014 |
20140162337 | ISOPRENE PRODUCTION USING THE DXP AND MVA PATHWAY - The invention provides for methods for producing isoprene from cultured cells using various components of the DXP pathway and MVA pathway, or components associated with the DXP pathway and MVA pathway, iron-sulfur cluster-interacting redox polypeptides, and isoprene synthase. The invention also provides compositions that include these cultured cells. | 06-12-2014 |
20140162322 | BIOLOGICAL PRODUCTION OF PENTOSE SUGARS USING RECOMBINANT CELLS - The invention provides, inter alia, compositions and methods for the biological production of pentose sugars, such as 2-methylerythritol (2-ME), 1-deoxyxylulose (1-DX), and monoacetylated-2-C-methylerythritols, using recombinant cells. | 06-12-2014 |
20140155660 | COMPOSITIONS AND METHODS FOR PRODUCING ISOPRENE FREE OF C5 HYDROCARBONS UNDER DECOUPLING CONDITIONS AND/OR SAFE OPERATING RANGES - The invention features methods for producing isoprene from cultured cells wherein the cells in the stationary phase. The invention also provides compositions that include these cultured cells and/or increased amount of isoprene. The invention also provides for systems that include a non-flammable concentration of isoprene in the gas phase. Additionally, the invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity. | 06-05-2014 |
20140154782 | Compositions and Methods Comprising Serine Protease Variants - The present invention provides serine protease variants, more specifically subtilisin variants produced there from. Specifically, the present invention provides serine protease variants, more specifically subtilisin variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants, more specifically subtilisin variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants, more specifically subtilisin variants. | 06-05-2014 |
20140148623 | FUEL COMPOSITIONS COMPRISING ISOPRENE DERIVATIVES - The invention provides for methods, compositions and systems using bioisoprene derived from renewable carbon for production of a variety of hydrocarbon fuels and fuel additives. | 05-29-2014 |
20140147902 | COMPOSITIONS AND METHODS FOR IMPROVED ISOPRENE PRODUCTION USING TWO TYPES OF ISPG ENZYMES - The invention provides for compositions and methods for producing isoprene by using recombinantly engineered cells that utilize a system of dual IspG enzymes in addition to isoprene synthase. | 05-29-2014 |
20140141971 | GRANULE WITH HYDRATED BARRIER MATERIAL - A granule having high stability and low dust is described. The granule includes a hydrated barrier material having moderate or high water activity. Also described are methods of producing the granules. | 05-22-2014 |
20140141448 | NOVEL 2,5-DIKETO-L-GLUCONIC ACID REDUCTASES AND METHODS OF USE - Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described. | 05-22-2014 |
20140135252 | DETERGENT COMPOSITIONS CONTAINING GEOBACILLUS TEPIDAMANS MANNANASE AND METHODS OF USE THEREOF - The present compositions and methods relate to an endo-B-mannanase cloned from | 05-15-2014 |
20140134708 | USE AND PRODUCTION OF STORAGE-STABLE NEUTRAL METALLOPROTEASE - The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from | 05-15-2014 |
20140134677 | METHOD FOR REDUCING VISCOSITY IN SACCHARIFICATION PROCESS - The present invention relates to compositions that can be used in hydrolyzing biomass such as compositions comprising a polypeptide having glycosyl hydrolase family 61/endoglucanase activity, methods for hydrolyzing biomass material, and methods for reducing viscosity of biomass mixture using a composition comprising a polypeptide having glycosyl hydrolase family 61/endoglucanase activity. | 05-15-2014 |
20140128645 | ENHANCED PRODUCTION OF ISOPRENE USING MARINE BACTERIAL CELLS - The invention provides for methods for the production of isoprene in recombinant marine bacterial cells via the heterologous expression of isoprene synthase enzymes. | 05-08-2014 |
20140127817 | FILAMENTOUS FUNGI HAVING AN ALTERED VISCOSITY PHENOTYPE - Described are compositions and methods relating to variant filamentous fungi having altered growth characteristics. Such variants are well-suited for growth in submerged cultures, e.g., for the large-scale production of enzymes and other proteins for commercial applications. | 05-08-2014 |
20140127770 | METHODS OF PRODUCING ISOPRENE AND A CO-PRODUCT - The invention features methods producing isoprene and a co-product, such as ethanol, 1,3-propanediol, or hydrogen from cultured cells. The invention also provides compositions that include these cultured cells. The invention provides compositions comprising isoprene and ethanol, isoprene and 1,3-propanediol, and isoprene and hydrogen. Additionally, the invention provides methods of co-producing isoprene and ethanol, isoprene and 1,3-propanediol, and isoprene and hydrogen by culturing cells under conditions suitable for co-production of isoprene and ethanol, isoprene and 1,3-propanediol, and isoprene and hydrogen. | 05-08-2014 |
20140127757 | HETEROLOGOUS ALPHA AMYLASE EXPRESSION IN ASPERGILLUS - The present invention relates to the co-expression and production of a heterologous alpha amylase and an endogenous glucoamylase in an | 05-08-2014 |
20140123404 | LACCASE VARIANTS HAVING INCREASED EXPRESSION AND/OR ACTIVITY - The present compositions, methods, and systems, relating to variant laccase enzymes that demonstrate increased expression and/or activity compared to a reference parental laccase enzyme. The variant enzymes include mutations that affect glycosylation, surface charge, or surface hydrophobicity, resulting in improved enzyme expression and/or enzyme activity. | 05-08-2014 |
20140113346 | THERMOSTABLE CARBONIC ANHYDRASES AND METHODS OF USE THEREOF - The present compositions and methods relate to a thermostable carbonic anhydrases, polynucleotides encoding the carbonic anhydrase, and methods of make and/or use thereof. Formulations containing the carbonic anhydrase are suitable for use in extracting carbon dioxide. | 04-24-2014 |
20140106416 | MANIPULATION OF GENES OF THE MEVALONATE AND ISOPRENOID PATHWAYS TO CREATE NOVEL TRAITS IN TRANSGENIC ORGANISMS - Disclosed are the uses of specific genes of the mevalonate and isoprenoid biosynthetic pathways, and of inactive gene sites (the pseudogene) to (1) enhance biosynthesis of isopentenyl diphosphate, dimethylallyl diphosphate and isoprenoid pathway derived products in the plastids of transgenic plants and microalgae, (2) create novel antibiotic resistant transgenic plants and microalgae, and (3) create a novel selection system and/or targeting sites for mediating the insertion of genetic material into plant and microalgae plastids. The specific polynucleotides to be used, solely or in any combination thereof, are publicly available from GeneBank and contain open reading frames having sequences that upon expression will produce active proteins with the following enzyme activities: (a) acetoacetyl CoA thiolase (EC 2.3.1.9), (b) 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) synthase (EC 4.1.3.5), (c) HMG-CoA reductase (EC 1.1.1.34), (d) mevalonate kinase (EC 2.7.1.36), (e) phosphomevalonate kinase (EC 2.7.4.2), (f) mevalonate diphosphate decarboxylase (EC 4.1.1.33), (g) isopentenyl diphosphate (IPP) isomerase (EC 5.3.3.2), and (h) phytoene synthase (EC 2.5.1.32). | 04-17-2014 |
20140106409 | CHIMERIC ALPHA-AMYLASE VARIANTS - Chimeric alpha-amylases having the characteristics of high thermostability and good performance in starch degradation, especially high-temperature liquefaction processes, are provided. The alpha-amylases are chimeras of AmyL and AmyS enzymes, and are useful in starch degradation processes. Methods of making the chimeric enzymes, and methods of using the chimeric alpha-amylases for liquefaction, cleaning starch residue from a surface, and treating woven material to remove coatings. Kits for practicing the methods are provided. Polynucleotides encoding the chimeric amylases, vectors, and expression hosts also are provided. | 04-17-2014 |
20140106408 | GLYCOSYL HYDROLASE ENZYMES AND USES THEREOF FOR BIOMASS HYDROLYSIS - The present invention relates to compositions that can be used in hydrolyzing biomass such as compositions comprising a polypeptide having glycosyl hydrolase (GH) family 61/endoglucanase activity and/or a β-glucosidase polypeptide, methods for hydrolyzing biomass material, and methods for using such compositions. | 04-17-2014 |
20140099721 | FILAMENTOUS FUNGI HAVING AN ALTERED VISCOSITY PHENOTYPE - Described are compositions and methods relating to variant filamentous fungi having altered growth characteristics. Such variants are well-suited for growth in submerged cultures, e.g., for the large-scale production of enzymes and other proteins for commercial applications. | 04-10-2014 |
20140099698 | THERMOLYSIN VARIANTS AND DETERGENT COMPOSITIONS THEREWITH - The present invention provides methods and compositions comprising at least one thermolysin-like neutral protease enzyme with improved storage stability and/or catalytic activity. In some embodiments, the thermolysin finds use in cleaning and other applications comprising detergent. In some particularly preferred embodiments, the present invention provides methods and compositions comprising thermolysin formulated and/or engineered to resist detergent-induced inactivation. | 04-10-2014 |
20140099677 | ALTERING ENZYME BALANCE THROUGH FERMENTATION CONDITIONS - This present disclosure relates to methods for improved production of proteins from a cell culture, particularly to culture components and conditions that can preferentially increase the expression of proteins produced from genes under the control of xylanase gene promoter sequences. The improved methods can be used for the production of enzyme compositions with enhanced xylanase and hem icellulolytic activity. | 04-10-2014 |
20140094587 | FILAMENTOUS FUNGI HAVING AN ALTERED VISCOSITY PHENOTYPE - Described are compositions and methods relating to variant filamentous fungi having altered growth characteristics. Such variants are well-suited for growth in submerged cultures, e.g., for the large-scale production of enzymes and other proteins for commercial applications. | 04-03-2014 |
20140087443 | OVER EXPRESSION OF FOLDASES AND CHAPERONES IMPROVES PROTEIN PRODUCTION - The present teachings provide methods for increasing protein secretion, e.g., chymosin in filamentous fungi by co-expressing certain chaperone(s) and/or foldase(s). The present teachings also provide filamentous fungi containing certain chaperone(s) and/or foldase(s) and a protein of interest for increased secretion. | 03-27-2014 |
20140087442 | GLUCOAMYLASE VARIANTS - The present invention relates to glucoamylase variants. In particular, the invention relates to variants in the starch binding domain (SBD) of a glucoamylase. The invention also relates to variants having altered properties (e.g., improved thermostability and/or increased specific activity) as compared to a corresponding parent glucoamylase. The present invention also provides enzyme compositions comprising the variant glucoamylases; DNA constructs comprising polynucleotides encoding the variants; and methods of producing the glucoamylase variants in host cells. | 03-27-2014 |
20140087430 | SINGLE PH PROCESS FOR STARCH LIQUEFACTION AND SACCHARIFICATION FOR HIGH-DENSITY GLUCOSE SYRUPS - Embodiments of the present disclosure relate to a process for producing downstream products, such as high-density glucose syrups and high-glucose fermentation feedstock, from a starch-containing substrate without a pH adjustment before the saccharification step. The saccharification is effectively catalyzed by a glucoamylase at a pH in the range of 5.2 to 5.6. | 03-27-2014 |
20140087429 | ALPHA-AMYLASE BLEND FOR STARCH PROCESSING AND METHOD OF USE THEREOF - The present disclosure relates to an enzyme blend comprising a low pH, thermostable alpha-amylase and a | 03-27-2014 |
20140085998 | COMPOSITION COMPRISING VARIOUS PROTEORHODOPSINS AND/OR BACTERIORHODOPSINS AND USE THEREOF - The present invention provides a solid material comprising an immobilized mixture of two or more proteorhodopsins, two or more bacteriorhodopsins, or one or more bacteriorhodopsin and one or more proteorhodopsins. The proteorhodopsins are selected from the group consisting of all-trans-retinal-containing proteorhodopsins and retinal analog-containing proteorhodopsins; all of which have absorption spectra that do not overlap. The bacteriorhodopsins are selected from the group consisting of all-trans-retinal-containing bacteriorhodopsins and retinal analog-containing bacteriorhodopsins; all of which have absorption spectra that do not overlap. The present invention also provides an optical information carrier, such as an optical data storage material and a fraud-proof optical data carrier, comprising the above-described solid material and a substrate selected from the group consisting of glass, paper, metal, fabric material, and plastic material, wherein said solid material is deposited on said substrate. The present invention further provides security ink comprising one or more hydrophilic polymers and a mixture of various photochromic materials. | 03-27-2014 |
20140080996 | SKIN OR HAIR BINDING PEPTIDES - The invention is directed to peptides. Specifically, the invention is directed to peptides which bind skin and do not bind hair. Alternatively, the invention is drawn to peptides which bind hair and do not bind skin. | 03-20-2014 |
20140080983 | POLYMERIZATION OF ISOPRENE FROM RENEWABLE RESOURCES - This invention relates to compositions and methods for producing polymers of isoprene derived from renewable resources, such as isoprene produced from cultured cells that use renewable carbon sources. A starting isoprene composition, such as a bioisoprene composition, is distinguished from petroleum based isoprene by its purity profile (such as lower levels of certain C | 03-20-2014 |
20140073548 | DETERGENT COMPOSITIONS CONTAINING BACILLUS SP. MANNANASE AND METHODS OF USE THEREOF - The present compositions and methods relate to an endo-B-mannanase cloned from a | 03-13-2014 |
20140073030 | DETERGENT COMPOSITIONS CONTAINING BACILLUS AGARADHAERENS MANNANASE AND METHODS OF USE THEREOF - The present compositions and methods relate to an endo-β-mannanase cloned from | 03-13-2014 |
20140073026 | SYSTEMS USING CELL CULTURE FOR PRODUCTION OF ISOPRENE - The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells. The invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity. Additionally, the invention provides methods of producing isoprene by culturing cells under conditions suitable for isoprene production while maintaining cell viability and/or metabolic activity. | 03-13-2014 |
20140073017 | CELLULASE COMPOSITIONS AND METHODS OF USING THE SAME FOR IMPROVED CONVERSION OF LIGNOCELLULOSIC BIOMASS INTO FERMENTABLE SUGARS - The present invention relates to compositions that can be used in hydrolyzing biomass such as compositions comprising a polypeptide having β-glucosidase activity, methods for hydrolyzing biomass material, and methods for improving the stability and saccharification efficacy of a composition comprising such β-glucosidase polypeptides and/or activity. | 03-13-2014 |
20140057324 | Variants of An Alpha-Amylase With Improved Production Levels in Fermentation Processes - Variants of | 02-27-2014 |
20140057015 | ENZYME GRANULE BLENDS CONSISTING ESSENTIALLY OF SODIUM SULFATE - The present teachings provide ways of improving the distribution of high payload enzyme granules by reducing their size, and by mixing them with size-matched dummy particles containing sodium sulfate. The present teachings also provide methods of using the mixtures. | 02-27-2014 |
20140045268 | Proteases With Modified Pro Regions - The present invention provides methods and compositions for the production of mature proteases in bacterial host cells. The compositions include modified polynucleotides that encode modified proteases, which have at least one mutation in the pro region; the modified serine proteases encoded by the modified polynucleotides; expression cassettes, DNA constructs, and vectors comprising the modified polynucleotides that encode the modified proteases; and the bacterial host cells transformed with the vectors of the invention. The methods include methods for enhancing the production of mature proteases in bacterial host cells e.g. | 02-13-2014 |
20140031272 | COMPOSITIONS - A composition comprising: (a) a lipolytic enzyme; (b) a hydrophobin, as defined herein; and optionally (c) a detergent; is provided. The composition is useful as a cleaning composition for removing lipid-based stains from surfaces. | 01-30-2014 |
20140024098 | EXPRESSION OF CATALASE IN TRICHODERMA - The invention provides methods for expression of a catalase enzyme in a | 01-23-2014 |
20140024067 | KEX2 Cleavage regions of recombinant fusion proteins - The invention relates to a fusion DNA construct comprising a KEX2 region comprising a KEX2 site and a KEX2 site pre-sequence immediately 5′ to the KEX2 site, a fusion polypeptide, vectors and cells comprising the fusion DNA construct, methods for producing desired proteins from filamentous fungal cells and methods for enhancing the secretion and/or cleavage of a desired protein from a cell. | 01-23-2014 |
20140011242 | METHOD FOR IMPROVING YIELD OF CELLULOSE CONVERSION PROCESSES - The present teachings provide methods of converting cellulosic materials to soluble sugars. Methods for increasing the yield of glucose from the enzymatic saccharification of cellulosic materials is also provided. The present teachings further provide methods of increasing the yield of cellobiose from the enzymatic saccharification of cellulosic materials. | 01-09-2014 |
20140007356 | COLOR MODIFICATION OF SIZED FABRIC - Described are methods relating to modifying the color of sized fabrics using a perhydrolase enzyme system, thereby elimination the need for prior desizing. | 01-09-2014 |
20140005094 | MULTIPLE MUTATION VARIANTS OF SERINE PROTEASE | 01-02-2014 |
20140004564 | COMPOSITIONS AND METHODS FOR IMPROVED PROTEIN PRODUCTION | 01-02-2014 |
20130337508 | BETA-GLUCOSIDASE ENHANCED FILAMENTOUS FUNGAL WHOLE CELLULASE COMPOSTIONS AND METHODS OF USE - The present disclosure provides beta-glucosidase enhanced filamentous fungal whole cellulase compositions. Also provided are methods of hydrolyzing a cellulosic material with beta-glucosidase enhanced whole cellulase compositions. The present disclosure further provides methods of decreasing the amount of a whole cellulase required to hydrolyze a cellulosic material by adding an effective amount beta-glucosidase. | 12-19-2013 |
20130330796 | IDENTIFICATION OF ISOPRENE SYNTHASE VARIANTS WITH IMPROVED PROPERTIES FOR THE PRODUCTION OF ISOPRENE - The invention provides for compositions and methods for producing isoprene using isoprene synthase variants with improved properties. | 12-12-2013 |
20130330709 | LEGUME ISOPRENE SYNTHASE FOR PRODUCTION OF ISOPRENE - The present invention provides methods and compositions of polypeptides having isoprene synthase activity with improved performance characteristics. In particular, the present invention provides legume isoprene synthases for increased isoprene production in recombinant host cells. | 12-12-2013 |
20130323816 | Protease Variants Active over a Broad Temperature Range - The present invention provides protease compositions particularly suited for dishwashing applications. | 12-05-2013 |
20130323798 | METHOD OF USING ALPHA-AMYLASE FROM ASPERGILLUS CLAVATUS FOR SACCHARIFICATION - A fungal α-amylase is provided from | 12-05-2013 |
20130309743 | CONVERSION OF PRENYL DERIVATIVES TO ISOPRENE - The present invention provides methods for producing derivatives from cultured cells. In addition, the present invention provides methods for conversion of prenyl derivatives, obtained from biological or petrochemical sources, to isoprene by employing chemical or biological catalysts. The present invention also provides compositions that include the cultured cells or isoprene or prenyl derivatives produced there from. | 11-21-2013 |
20130295632 | ISOPRENE SYNTHASE VARIANTS WITH IMPROVED SOLUBILITY FOR PRODUCTION OF ISOPRENE - The present invention provides methods and compositions of variant polypeptides having isoprene synthase activity with improved solubility. In particular, the present invention provides isoprene synthase variant for increased isoprene production in recombinant host cells. | 11-07-2013 |
20130288332 | SMALL ENZYME-CONTAINING GRANULES - The invention provides small enzyme-containing granules having an inorganic salt core and an enzyme-containing layer coated over the core, and methods for producing such granules. The majority of the enzyme granules are less than 300 μm in diameter. The granules are suitable for incorporation into compositions such as cleaning, textile processing, and animal feed compositions. | 10-31-2013 |
20130269118 | LOCAL COLOR MODIFICATION OF DYED FABRICS USING A LACCASE SYSTEM - The present systems, compositions, and methods relate to local color modification of dyed fabrics using a laccase enzyme system. | 10-17-2013 |
20130260438 | COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS (AS AMENDED) - The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants. | 10-03-2013 |
20130260432 | ISOPRENE SYNTHASE VARIANTS FOR IMPROVED MICROBIAL PRODUCTION OF ISOPRENE - The present invention provides methods and compositions comprising at least one isoprene synthase enzyme with improved catalytic activity and/or solubility. In particular, the present invention provides variant plant isoprene synthases for increased isoprene production in microbial host cells. Biosynthetically produced isoprene of the present invention finds use in the manufacture of rubber and elastomers. | 10-03-2013 |
20130253141 | POLYMERS OF ISROPENE FROM RENEWABLE RESOURCES - It has been found that certain cells in culture can convert more than about 0.002 percent of the carbon available in the cell culture medium into isoprene. These cells have a heterologous nucleic acid that (i) encodes an isoprene synthase polypeptide and (ii) is operably linked to a promoter. The isoprene produced in such a cultured medium can then be recovered and polymerized into synthetic rubbers and other useful polymeric materials. The synthetic isoprene containing polymers of this invention offer the benefit of being verifiable as to being derived from non-petrochemical based resources. They can also be analytically distinguished from rubbers that come from natural sources. The present invention more specifically discloses a polyisoprene polymer which is comprised of repeat units that are derived from isoprene monomer, wherein the polyisoprene polymer has δ | 09-26-2013 |
20130252303 | THREE-DIMENSIONAL STRUCTURE OF ISOPRENE SYNTHASE AND ITS USE THEREOF FOR GENERATING VARIANTS - The present invention provides a three-dimensional structures of | 09-26-2013 |
20130244289 | VARIANT HUMICOLA GRISEA CBH1.1 - Disclosed are variants of | 09-19-2013 |
20130224864 | FILAMENTOUS FUNGI HAVING AN ALTERED VISCOSITY PHENOTYPE - Described are compositions and methods relating variant filamentous fungi having altered growth characteristics. Such variants are well-suited for growth in submerged cultures, e.g., for the large-scale production of enzymes and other proteins for commercial applications. | 08-29-2013 |
20130224831 | Dish Detergent Comprising Bleaching Enzymes - Described are compositions and methods that involve using bleaching enzymes in dish detergents. In some preferred embodiments, the bleaching enzyme comprises at least one laccase, while in some alternative preferred embodiments, the bleaching enzyme comprises at least one glucose oxidase suitable for use in dish detergents. In some additional preferred embodiments, the dish detergents are machine dish detergents. | 08-29-2013 |
20130217093 | PERHYDROLASE EPITOPES - The present invention provides perhydrolase enzyme CD4+ T-cell epitopes, as well as novel variants that exhibit reduced immunogenic responses, as compared to the parental perhydrolase. The present invention further provides DNA molecules that encode novel perhydrolase variants, and host cells comprising DNA encoding novel perhydrolase variants, as well as methods for making perhydrolase enzymes less immunogenic. In addition, the present invention provides various compositions that comprise perhydrolase variants that are less immunogenic than the wild-type perhydrolase. In some specific embodiments, the present invention provides perhydrolase variants with reduced immunogenicity identified and/or characterized using the methods of the present invention. These enzymes find use in cleaning and other applications. In some preferred embodiments, the present invention finds particular use in applications involving cleaning, bleaching and disinfecting. | 08-22-2013 |
20130216519 | PROTEASES PRODUCING AN ALTERED IMMUNOGENIC RESPONSE AND METHODS OF MAKING AND USING THE SAME - The present invention provides novel protein variants that exhibit reduced immunogenic responses, as compared to the parental proteins. The present invention further provides DNA molecules that encode novel variants, host cells comprising DNA encoding novel variants, as well as methods for making proteins less allergenic. In addition, the present invention provides various compositions that comprise these proteins that are less immunogenic than the wild-type proteins. | 08-22-2013 |
20130203140 | PRODUCTION OF ISOPRENOIDS UNDER NEUTRAL pH CONDITIONS - Embodiments of the present disclosure relate to a process for producing isoprenoid precursor molecules and/or isoprenoids from a starch substrate by saccharification and/or fermentation. The saccharification is effectively catalyzed by a glucoamylase at a pH in the range of 5.0 to 8.0. At a pH of 6.0 or above, the glucoamylase possesses at least 50% activity relative to its maximum activity. The saccharification and fermentation may be performed as a simultaneous saccharification and fermentation (SSF) process. | 08-08-2013 |
20130203135 | MULTIMERIC OXIDOREDUCTASES - The present invention concerns multimeric oxidoreductase complexes which function in the enzymatic conversion of a carbon substrate, said complexes having a dehydrogenase subunit and a cytochrome C subunit. The invention further relates to polynucleotides coding for the multimeric complexes and methods of use thereof. | 08-08-2013 |
20130196891 | Polyol Oxidases - The present invention provides compositions and methods for producing a polyol oxidase in micoroorganisms, and the use of polyol oxidases in cleaning compositions. The invention includes cleaning compositions that contain combinations of two or more POx oxidases, and cleaning compositions that contain combinations of two or more POx oxidases and a perhydrolase. In particular, the invention provides methods for expressing polyol oxidases in bacterial hosts for use in detergent applications for cleaning, bleaching and disinfecting. | 08-01-2013 |
20130196402 | COMPOSITIONS AND METHODS FOR PRODUCING ISOPRENE FREE OF C5 HYDROCARBONS UNDER DECOUPLING CONDITIONS AND/OR SAFE OPERATING RANGES - The invention features methods for producing isoprene from cultured cells wherein the cells in the stationary phase. The invention also provides compositions that include these cultured cells and/or increased amount of isoprene. The invention also provides for systems that include a non-flammable concentration of isoprene in the gas phase. Additionally, the invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity. | 08-01-2013 |
20130195781 | Modified Variant Bowman Birk Protease Inhibitors - The present invention relates to modified variant Bowman Birk Protease Inhibitor proteins (BBPIs) that comprise peptides that bind target proteins, and that are further modified to have greater protease inhibitory activity and/or be produced at greater yields than the unmodified BBPIs. The invention encompasses polynucleotide constructs and expression vectors containing polynucleotide sequences that encode the modified variant BBPIs, the transformed host cells that express and produce the modified variant BBPIs, the modified variant BBPI proteins, the compositions comprising the modified variant BBPIs, and the methods for making and using the modified variant BBPIs in personal care. | 08-01-2013 |
20130177965 | BGL7 Beta-Glucosidase and Nucleic Acids Encoding the Same - The present invention provides a novel β-glucosidase nucleic acid sequence, designated bgl7, and the corresponding BGL7 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL7, recombinant BGL7 proteins and methods for producing the same. | 07-11-2013 |
20130177964 | AMYLASE FROM NESTERENKONIA AND METHODS OF USE, THEREOF - Compositions and methods relating to an alpha-amylase enzyme obtained from | 07-11-2013 |
20130177947 | NOVEL GLYCOSYL HYDROLASE ENZYMES AND USES THEREOF - The present disclosure is generally directed to glycosyl hydrolase enzymes, compositions comprising such enzymes, and methods of using the enzymes and compositions, for example for the saccharification of cellulosic and hemicellulosic materials into sugars. | 07-11-2013 |
20130175196 | ENZYME FABRIC CARE TABLETS FOR CONSUMERS AND METHODS - Single-dose enzyme tablets for direct sale to consumers are provided for boosting the performance of automatic laundry and dish washing operations using conventional detergents. The tablets provide a wash performance that is better than or at least equal to the wash performance of the detergents alone even when the time and or temperature of the wash cycle is decreased. The tablets may be provided in kits and the enzymes are selected to treat a variety of fabric stains as well as to provide fabric care benefits. | 07-11-2013 |
20130171717 | Multiply-Substituted Protease Variants - Novel enzyme variants including protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occurring or recombinant protease to generate the substitution of a plurality of amino acid residues in the amino acid sequence of a precursor protease. Such variant proteases have properties which are different from those of the precursor protease, such as altered wash performance. The substituted amino acid residue correspond to positions 27, 45, 170, 181, 251 and 271 of | 07-04-2013 |
20130164809 | PRODUCTION OF ISOPRENE UNDER REDUCED OXYGEN INLET LEVELS - This invention relates to methods for producing isoprene by culturing recombinant cells (e.g., cells engineered to produce isoprene) under reduced oxygen inlet levels. | 06-27-2013 |
20130164808 | ENHANCED PRODUCTION OF ISOPRENE USING HOST CELLS HAVING DECREASED ISPA ACTIVITY - This invention relates to recombinant microorganisms capable of producing isoprene and isoprene production with the use of such recombinant microorganism with good efficiency. In this invention, functional activity of the ispA gene is altered to reduce the production of isoprenoid molecules in recombinant cells engineered to produce isoprene or in cells otherwise susceptible to isoprenoid accumulation during fermentation. This decreased ispA gene functional activity enables enhanced synthesis of isoprene in a host microorganism. | 06-27-2013 |
20130157341 | Multiply-Substituted Protease Variants - Novel protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occurring or recombinant protease to generate the substitution of a plurality of amino acid residues in the amino acid sequence of a precursor protease. Such variant proteases have properties which are different from those of the precursor protease, such as altered wash performance. The substituted amino acid residue equivalent to positions 7, 23, 26, 28, 29, 30, 31, 47, 66, 69, 73, 82, 85, 88, 90, 92, 93, 105, 113, 139, 148, 149, 150, 151, 178, 200, 201, 231, 233, 267 and/or 273 of | 06-20-2013 |
20130149770 | Variant Alpha-Amylases from Bacillus Subtilis and Methods of Uses, Thereof - Alpha-amylases from | 06-13-2013 |
20130149742 | FILAMENTOUS FUNGAL HOST STRAINS AND DNA CONSTRUCTS, AND METHODS OF USE THEREOF - The present disclosure relates to filamentous fungal host strains and recombinant DNA constructs for creation and use thereof. The filamentous fungal host strains are particularly useful for achieving reliable expression of recombinant enzymes and variants. | 06-13-2013 |
20130143301 | BETA-GLUCOSIDASE I VARIANTS WITH IMPROVED PROPERTIES - The present disclosure is generally directed to enzymes and in particular beta-glucosidase variants. Also described are nucleic acids encoding beta-glucosidase variants, compositions comprising beta-glucosidase variants, methods of using beta-glucosidase variants, and methods of identifying additional useful beta-glucosidase variants. | 06-06-2013 |
20130143277 | Methods for Improving the Efficiency of Simultaneous Saccharification and Fermentation Reactions - The present disclosure is directed, in a first aspect, to the use of inverting beta-xylosidase enzymes to reduce byproduct formation and increase the yield of fermentation products, as well as, in a second aspect, to the use of retaining beta-xylosidase enzymes to improve production of alkyl-beta-xylopyranoside compounds, in a simultaneous saccharification and fermentation reactions. | 06-06-2013 |
20130142903 | FOOD PRODUCT COMPRISING A LOW TEMPERATURE RICE PROTEIN CONCENTRATE - Rice protein concentrates prepared at low temperature exhibit improved functionality and beneficial physiological benefits, including lowered cholesterol and enhanced lactic acid dehydrogenase activity, without an increase in blood urea nitrogen. The rice protein concentration could be made into a wet dough with comparatively less water than a soy protein concentrate. Use of the rice protein concentrate thus improved processing steps in the formulation of a food article containing the concentrate. The food product advantageously shows an extending shelf life and improved palatable texture. | 06-06-2013 |
20130135979 | COMPOSITION COMPRISING VARIOUS PROTEORHODOPSINS AND/OR BACTERIORHODOPSINS AND USE THEREOF - The present invention provides a solid material comprising an immobilized mixture of two or more proteorhodopsins, two or more bacteriorhodopsins, or one or more bacteriorhodopsin and one or more proteorhodopsins. The proteorhodopsins are selected from the group consisting of all-trans-retinal-containing proteorhodopsins and retinal analog-containing proteorhodopsins; all of which have absorption spectra that do not overlap. The bacteriorhodopsins are selected from the group consisting of all-trans-retinal-containing bacteriorhodopsins and retinal analog-containing bacteriorhodopsins; all of which have absorption spectra that do not overlap. The present invention also provides an optical information carrier, such as an optical data storage material and a fraud-proof optical data carrier, comprising the above-described solid material and a substrate selected from the group consisting of glass, paper, metal, fabric material, and plastic material, wherein said solid material is deposited on said substrate. The present invention further provides security ink comprising one or more hydrophilic polymers and a mixture of various photochromic materials. | 05-30-2013 |
20130122569 | Expression of Granular Starch Hydrolyzing Enzymes in Trichoderma and Process for Producing Glucose from Granular Starch Sustrates - The present invention relates to filamentous fungal host cells and particularly | 05-16-2013 |
20130122562 | PRODUCTION OF ISOPRENE, ISOPRENOID PRECURSORS, AND ISOPRENOIDS USING ACETOACETYL-COA SYNTHASE - This invention relates to a recombinant microorganism capable of producing isoprene and isoprene production with the use of such recombinant microorganism with good efficiency. In this invention, the acetoacetyl-CoA synthase gene encoding an enzyme capable of synthesizing acetoacetyl-CoA from malonyl-CoA and acetyl-CoA and one or more genes involved in isoprene biosynthesis that enables synthesis of isoprene from acetoacetyl-CoA are introduced into a host microorganism. | 05-16-2013 |
20130115659 | COMPOSITIONS AND METHODS FOR GRAIN PROCESSING WITHOUT PH ADJUSTMENT - Described are compositions and methods relating to starch processing without a phytase pretreatment step and without adjustment of the slurry pH adjustment. | 05-09-2013 |
20130115297 | STABLE, DURABLE GRANULES WITH ACTIVE AGENTS - A stable, durable granule for feed compositions has a core, at least one active agent; and at least one coating. The active agent of the granule retains at least 50% activity, at least 60% activity, at least 70% activity, at least 80% activity after conditions selected from one or more of a) a feed pelleting process, b) a steam-heated feed pretreatment process, c) storage, d) storage as an ingredient in an unpelleted mixture, and e) storage as an ingredient in a feed base mix or a feed premix comprising at least one compound selected from trace minerals, organic acids, reducing sugars, vitamins, choline chloride, and compounds which result in an acidic or a basic feed base mix or feed premix. | 05-09-2013 |
20130111674 | TREATMENT OF KERATINOUS FIBERS WITH AN ENZYME HAVING PERHYDROLASE ACTIVITY - Described are compositions and methods relating to the treatment of keratinous fibers and textiles comprising such fibers with enzymatically-generated peracids in aqueous media. The treatment has beneficial effects, including reducing felting, increasing dye uptake, and reducing prickling tendency. | 05-09-2013 |
20130102757 | METHODS FOR SELECTIVE TARGETING - A selective targeting method is disclosed comprising contacting a library of ligands, particularly a peptide library, with an anti-target to allow the ligands to bind to the anti-target; separating the non-binding ligands from the anti-target bound ligands, contacting the non-binding anti-target ligands with a target allowing the unbound ligands to bind with the target to form a target-bound ligand complex; separating the target-bound ligand complex from ligands which do not bind to the target, and identifying the target-bound ligands on the target-bound ligand complex wherein the target-bound ligands have a K | 04-25-2013 |
20130102052 | MODIFIED SECRETION SYSTEM TO INCREASE EXPRESSION OF POLYPEPTIDES IN BACTERIA - The present invention provides methods of altering the production of desired polypeptides in a host cell. In particular, the present invention provides polynucleotides encoding truncated SecG proteins capable of facilitating the secretion of desired proteases by a bacterial host cell, such as | 04-25-2013 |
20130084618 | PHENOLIC BINDING PEPTIDES - The present application relates to peptides which bind to tannin, polyphenolic or anthocyanin compounds, and particularly to tea and wine stains on a fabric or other surface. The invention also concerns binding peptide conjugates which includes a binding peptide coupled to an agent and the use of the binding peptide conjugate for delivering an agent to a desired target. | 04-04-2013 |
20130078699 | COMPOSITIONS AND METHODS FOR PRODUCING ISOPRENE - The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells. | 03-28-2013 |
20130071908 | COMPOSITIONS AND METHODS FOR PRODUCING ISOPRENE - The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells. | 03-21-2013 |