COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH Patent applications |
Patent application number | Title | Published |
20160122360 | TETRAHYDRO-2H-PYRANO[3,2-C]ISOCHROMENE-6-ONES AND ANALOGS FOR THE TREATMENT OF INFLAMMATORY DISORDERS - The present invention relates to 2,3,4,4a-tetrahydro-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxypyrano[3,2-c]isochromen-6(10bH)-one analogs of the Formula I, wherein, R, R′ and R″ are as herein described. In addition, the invention relates to methods of using compounds for treating or preventing various inflammatory disorders such as rheumatoid arthritis, inflammatory bowel disease, psoriasis, asthma and chronic obstructive pulmonary disorder. | 05-05-2016 |
20160122195 | A SOL-GEL PROCESS FOR SYNTHESIS OF NANOCRYSTALLINE OXIDES - A Continuous flow synthesis of nanocrystalline metal oxides by rapid sol-gel process is disclosed. The process disclosed uses an impinging microjet micromixer device to obtain the nano crystalline metal oxides. A method of fabricating and assembling the impinging microjet micromixer is also disclosed herewith. | 05-05-2016 |
20160115179 | SPIRO-OXAZINES, INDOLINONES AND PREPARATION THEREOF - The present invention relates to novel spiro-oxazine analogues of Formula-I and Indolinone compounds of Formula-II or positional isomers, or stereoisomers, or derivatives, or pharmaceutically acceptable salt thereof. Formula-I Formula-II Further the invention provides transition-metal free multicomponent reaction (MCR) process for the preparation of said compounds of Formula-I and II using aryne precursor, N-substituted isatin and N-heteroaromatic compound as the nucleophile, under mild condition leading to formation of desired complex of spiro-oxazine analogues (I) and indolinone analogues (II) in high yield and selectivity. | 04-28-2016 |
20160107149 | COMPOSITION FOR ENHANCED LIFE TIME OF CHARGE CARRIERS FOR SOLAR HYDROGEN PRODUCTION FROM WATER SPLITTING - Disclosed herein are nanocomposite compositions comprising nano metal cluster containing titania and anion doped titania prepared by a simple one step for enhanced life time of charge carriers. | 04-21-2016 |
20160060183 | GIBBERELLIC ACID (GA3) FREE KAPPAPHYCUS ALVAREZII SAP AND ITS APPLICATION THEREOF - The present invention relates to a product | 03-03-2016 |
20160059228 | SEMICONDUCTOR-OXIDES NANOTUBES-BASED COMPOSITE PARTICLES USEFUL FOR DYE-REMOVAL AND PROCESS THEREOF - Semiconductor-oxide nanotubes-based composite particles are useful for dye-removal. A method involves an ion-exchange mechanism operating under a dark-condition in an aqueous solution, for the processing of products consisting of the nanotubes of semiconductor-oxides deposited on, anchored to or attached to the surface of fly ash particles and metal-oxide (magnetic and non-magnetic) nanoparticles. The resulting micro-nano and nano-nano integrated composite particles can be used in the removal of an organic synthetic-dye from an aqueous solution and industry effluent via a surface-adsorption process, involving ion-exchange and electrostatic-attraction mechanisms. The composite particles can be recycled for the next cycle of dye-adsorption by decomposing the previously adsorbed dye on their surfaces via the use of either noble-metal-deposited or magnetically separable magnetic photocatalysts and exposure to ultraviolet (UV) or solar-radiation. | 03-03-2016 |
20160039755 | OXINDOLE COMPOUNDS, SOLVENT-FREE SYNTHESIS AND USE THEREOF - The present invention discloses oxindole compounds and a single step, one pot reaction for the synthesis of oxindole derivates via a solvent free Passerini reaction of isocyanides, isatins and carboxylic acids. | 02-11-2016 |
20150368181 | RECYCLABLE CHIRAL CATALYST FOR ASYMMETRIC NITROALDOL REACTION AND PROCESS FOR THE PREPARATION THEREOF - The present invention relates to preparation of highly efficient chiral recyclable homogeneous catalysts generated in situ by the reaction of chiral oligomeric [H | 12-24-2015 |
20150367294 | PROCESS FOR THE PREPARATION OF MOFS-POROUS POLYMERIC MEMBRANE COMPOSITES - Disclosed herein is an in-situ process for the preparation of Metallic Organic Framework's (MOF's)—polymer composites at room temperature, without requirement of pre-seeding o MOF's or substrate modification. Further, the invention provides MOF-polymer composites membranes, wherein MOF forms a layer substantially covering the porosity of the membrane. | 12-24-2015 |
20150344672 | Carboxylate-Alumoxanes Nucleating Agents and a Process for the Preparation Thereof - The present invention disclose an improved carboxylate-alumoxanes nano sheets nucleating agent of formula (I), for advanced nucleation of thermoplastic semi-crystalline polymer, at low concentration; [Formula should be inserted here] where 2x+y+z=3 wherein; G represents a Phenyl ring or Naphthyl ring or fused aromatic rings R is independently selected from the group consisting of H,(C | 12-03-2015 |
20150342191 | CYCLIC AZA-SILA COMPOUNDS AS INSECT REPELLANTS - The invention relates to aza-sila compounds of Formula (I), useful as insect repellants. wherein, ‘A’ is selected from the group consisting of branched or unbranched (C1-C12) alkyl, branched or unbranched (C1-C12) alkynyl; and substituted or unsubstituted 4 to 6 membered acyclic saturated or unsaturated compounds, wherein the substituents are selected from the group consisting of halogen, hydrogen, (C1-C6) alkyl, aryl, arylalkyl and heterocyclic; or ‘A’ is independently selected from the group consisting of the following moiety: Formula (II) wherein, X and Y are identical or different and independently selected from the group consisting of —C—, —N, —O, and —S; where R1, R2, R3, and R4 are identical or different and are independently selected from the group consisting of hydrogen, halogen, linear or branched (C1-C6) alkyl, aryl, arylalkyl, hydroxyl, and heterocyclic; and wherein, the halogen is selected from the group consisting of —Cl, —I, —Br, and —F. The invention further discloses a process for the preparation of the compounds of Formula (I). | 12-03-2015 |
20150337000 | Mannose-Receptor Selective Lysinylated Cationic Amphiphiles and a Process for Preparation Thereof - The present invention relates to the mannose-receptor selective lysinylated cationic amphiphile and a process for preparation thereof. The compounds of the present invention can target DNA vaccines to antigen presenting cells (APCs) such as macrophages and dendritic cells (DCs), via mannose receptors expressed on the cell surface of APCs. The cationic amphiphiles disclosed herein show enhanced cellular and humoral immune response compared to their mannosyl counterparts in genetic immunization in mice. The present invention discloses that immunization with electrostatic complexes (lipoplexes) of DNA vaccines encoding melanoma antigens (gp100 and tyrosinase) and liposome of the presently described novel lysinylated cationic amphiphiles with mannose-mimicking shikimoyl head-groups provides long-lasting (100 days post melanoma tumor challenge) protective immunity in all immunized mice. Cationic amphiphiles with mannose-mimicking shikimoyl head-groups described in the present invention are likely to find future applications in the field of genetic immunization. | 11-26-2015 |
20150336090 | NOVEL OXIDATION CATALYST, THE PROCESS FOR THE PREPARATION THEREOF AND GREEN PROCESS FOR SELECTIVE AEROBIC OXIDATION - Described herein is a novel, cost effective, stable and recyclable catalyst composition i.e. A-B-OMS, wherein ‘A’ is selected from noble and transition metals; ‘B’ is selected from alkali or alkaline earth metals; and OMS is octahedral molecular sieve which includes synthetic todorokite (OMS-1) and cryptomelane (OMS-2); and characterization thereof. Further the invention provides base free green process for selective aerobic oxidation of 5-hydroxymethylfurfural (HMF) catalysed by said catalyst composition under optimized reaction conditions to obtain high yield of 2,5-furandicarboxylic acid (FDCA) in a shorter span of time. Invention also provides for selective oxidation of glucose to Gluconic Acid, furfural to furoic Acid and glycerol to Glyceric acid. Invention can also applicable for the selective oxidation of hexoses, pentoses, disaccharides to corresponding acids. | 11-26-2015 |
20150328170 | SYNERGISTIC PHARMACEUTICAL COMPOSITION USEFUL FOR THE TREATMENT OF LUNG CANCER - The present invention relates to a synergistic pharmaceutical composition comprising Compound C2 (Neo-isopulegol), C3 (Iso-pulegol) and C4 (Citronellol) derived from herbal seed extract of | 11-19-2015 |
20150322418 | RECOMBINANT MESO-ACTIVE THERMO-STABLE PROTEIN AND PROCESSES OF DESIGN AND BIOSYNTHESIS THEREOF - The present invention deals with examination of the alterability of part, or whole, of the surfaces of beta sheet-based protein structures, focusing especially on enzymes. The alteration is done by supplanting/transplanting a part, or whole, of the surface of one protein onto the surface of a homologous protein of superimposable polypeptide backbone, by exploiting the structural features of beta sheets to alter only the regions of the surface involved in substrate/ligand binding and catalysis. The transplantation involves replacement of a selected set of non-contiguous residues constituting the surface regions desired to be altered in one enzyme/protein, by a set of non-contiguous residues located at analogous positions in the other enzyme/protein, in a manner that is likely to facilitate folding and function of the new protein formed by combining residues from both enzymes/proteins. The present invention also deals with using this surface engineering approach to selectively combine enzyme/protein characteristics from different domains of life that are not ordinarily combined by natural evolution, such as the creation of novel proteins that retains the bulk of the thermostable scaffold of a thermophile enzyme onto which the active surface of a mesophile homolog is transplanted, so as to create a thermo-stable protein with meso-active functional characteristics of pH and temperature of optimal function. | 11-12-2015 |
20150299154 | SINGLE STEP ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CHIRAL PHTHALIDES - The present invention discloses single step, highly enantioselective catalytic oxidative cyclization process for the synthesis of 3-substituted chiral phthalides. In particular, the invention discloses asymmetric synthesis of chiral phthalides via synergetic nitrile accelerated oxidative cyclization of o-cyano substituted aryl alkenes in high yield and enantiomeric excess (ee) in short reaction time. Also, disclosed herein is “one-pot” asymmetric synthesis of biologically important natural compounds having 3-substituted chiral phthalide structural framework in the molecule. | 10-22-2015 |
20150298116 | MIXED METAL OXIDIC NANO SHEETS COATED MONOLITHIC CATALYSTS USEFUL FOR THE DECOMPOSITION OF TOXIC N2O AND A PROCESS FOR THE PREPARATION THEREOF - The present invention describes process of preparation of inter-polymer film of p-methylstyrene-co-divinylbenzene and its conversion into anion exchange membrane through a greener route which dispenses with the use of chloromethyl ether. The membrane with polyethylene binder is shown to have equivalent or even superior performance to anion exchange membrane prepared from styrene-co-divinylbenzene/polyethylene through chloromethyl ether route. | 10-22-2015 |
20150290595 | MODIFIED THIN FILM COMPOSITE REVERSE OSMOSIS MEMBRANE AND A PROCESS FOR PREPARATION THEREOF - The present invention relates to a complete process for preparation of high flux and salt rejection thin film composite (TFC) reverse osmosis (RO) membrane including process for preparation of support membrane for thin film, process for thin film coating of support membrane by in-situ interfacial polymerization between diamines and trimesoyl chloride, machine design, chemistry and details of process (engineering+chemistry+ambient) parameter at 1×100 sqm scale upgradable to a scale even 10-20 times higher. The produced membrane is characterized by 96% salt rejection and 48 LM-2H 1 flux with 2000 ppm sodium chloride solution at 250 psi pressure and 95% salt rejection and 46 LM2H 1 flux with 35000 ppm sodium chloride solution at 900 psi pressure. The present invention also relates to complete machine design for PSF ultrafiltration membrane casting and coating for TFC membrane production at commercial level. | 10-15-2015 |
20150274942 | BIODEGRADABLE HYDROPHOBIC COMPOSITE MATERIALS AND PROCESS FOR THE PREPARATION THEREOF - The present invention relates to biodegradable hydrophobic composite materials and a process for the preparation of said hydrophobic biodegradable materials from the seaweed polysaccharides through grafting reaction with vinylated monomers e.g. vinyl acetate. The said composites can be used as a substitute for synthetic ropes for varied applications including seaweed cultivation in the open sea. The results of cultivation experiments showed that ropes are suitable for cultivation of seaweeds in the sea environment, and exhibit higher biomass yield as compared to synthetic ropes. The prepared composites are very flexible and can be used for making handles for carry bags and for the preparation of biodegradable designs, bowls, pots, jars, gift items, stud caps and bracelets. | 10-01-2015 |
20150259372 | 10-a/BETA-D-ARABINOFURANOSYL-UNDECENES AS POTENTIAL ANTI-MYCOBACTERIAL AGENTS AND PROCESS FOR THE PREPARATION THEREOF - Disclosed herein is 10-α/β-D-Arabinofuranosylundecenes of general Formula (II) or pharmaceutically acceptable | 09-17-2015 |
20150218009 | NOVEL PROCESS FOR PREPARATION OF SYNTHETIC HYDROTALCITE FROM INDUSTRIAL WASTE - Development of a novel process for preparation of synthetic hydrotalcite using three industrial wastes such as aluminium chloride waste-generated in any of reaction where anhydrous aluminium chloride is used as Leawis acid catalyst such as Freidel Craft reaction, bittern containing magnesium compounds generated in solar salt work using brines such as sea brine and subsoil brines containing magnesium, and ammonium carbonate solution generated in organic pigment industries such as producing copper pthalo cyanin green. The process involves preparation of aluminium precursor and removing metallic impurities present in Aluminium hydroxide prepared from aluminium chloride containing waste, preparation of magnesium precursor, mixing the precursors, hydrothermally treating the mixture and adding surface modifying agents followed by filtration and drying. | 08-06-2015 |
20150203365 | PROCESS FOR DECOMPOSITION OF ORGANIC SYNTHETIC-DYES USING SEMICONDUCTOR-OXIDES NANOTUBES VIA DARK-CATALYSIS - In the present invention nanotubes-based dye-adsorbent powder is used for adsorption and decomposition of synthetic dye under dark-condition without the use of any external power-source such as the applied potential-difference, microwave, ultrasonicator, and others to save the energy consumption, which results in a complete dye-decomposition on the powder-surface. The surface-cleaned dye-adsorbent powder has very high specific surface-area and dye-adsorption capacity comparable with those of the original dye-adsorbent powder and can be recycled for the next cycles of dye-adsorption and dye-decomposition under the dark-condition. In the present method, the nanotubes-based dye-adsorbent powder is stirred under the dark-condition in an aqueous dye solution containing a strong oxidizer to get simultaneous dye-adsorption and dye-decomposition on the powder-surface, or getting dye adsorption in one solution and dye decomposition in a separate solution by said adsorbent powder under dark condition. | 07-23-2015 |
20150198576 | Composition for the Calorimetric Detection of Water in Hydrocarbon Fuels and a Process for the Preparation Thereof - The embodiments of the present invention disclose a composition for the colorimetric detection of water in hydrocarbon fuels and a process for the preparation thereof. The embodiments of the present invention relate to an improved method for determining the presence or absence of water in non-polar organic fluids such as petroleum oil or hydrocarbon oils by using an indicator system containing a water insoluble wetting agent and a water soluble dye which can be performed rapidly without costly instrumentation and tedious, time consuming analytical methods. | 07-16-2015 |
20150159180 | PROCESS FOR PRODUCTION OF CRYSTALLINE XYLITOL USING PICHIA CARIBBICA AND ITS APPLICATION FOR QUORUM SENSING INHIBITION - The inventors disclose a novel room temperature process for the synthesis of crystalline xylitol with high yield and purity from D-xylose using | 06-11-2015 |
20150141690 | PROCESS FOR MAKING DIMETHYL CARBONATE - An eco-friendly process for making dimethyl carbonate comprising contacting methanol with carbon dioxide in the presence of a solid, calcined catalyst derived from zirconium phosphonate catalyst having molecular formula: Zr(X) | 05-21-2015 |
20150141657 | 2-PHENYL BENZOTHIAZOLE LINKED IMIDAZOLE COMPOUNDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides 2-phenyl benzothiazole linked imidazole compounds of formula A as anti cancer agent against fifty three human cancer cell lines. | 05-21-2015 |
20150113793 | METHOD TO DESIGN A SECURITY FEATURE ON THE SUBSTRATE OF SECURITY DOCUMENTS USING SUB WAVELENGTH GRATING - Method of designing a security thread in security documents with better color contrast at any viewing angle is claimed. The invention discloses designing of security thread in security documents like bank notes using subwavelength gratings with period and thickness less than the wavelength of light. The sub wavelength gratings preferably asymmetric are designed such that the O | 04-30-2015 |
20150110662 | BORON DOPED MANGANESE ANTIMONIDE AS A USEFUL PERMANENT MAGNET MATERIAL - Permanent magnets are used for several important applications, including de electrical motors, wind turbines, hybrid automobile, and for many other applications. Modern widely used rare-earth based permanent magnet materials, such as Sm—Co and Nd—Fe—B, are generally intermetallic alloys made from rare earth elements and transition metals such as cobalt. However, the high costs of rare earth elements make the widespread use of these permanent magnets commercially unattractive. The present work focuses on producing a new permanent magnet material, with good magnetic properties, which is free from rare-earth elements and thus cost-effective. The present invention provides a process to synthesis boron doped manganese antimonide as an alternative to rare earth based permanent magnet materials. The boron doped manganese antimonide disclosed in this invention is free from rare-earth element with good magnetic properties. The material in the present study has been synthesized employing sequential combination of high energy ball milling, arc melting under argon atmosphere and again high energy ball milling followed by annealing. The annealed boron doped manganese antimonide shows improved magnetic properties as compared to manganese antimonide. | 04-23-2015 |
20150099900 | PROCESS FOR PRODUCING AMIDE COMPOUNDS - An efficient and eco-friendly process for producing amide compounds comprising contacting a primary amine with molecular oxygen-containing gas, solvent and ammonia solution in the presence of a non-precious metal-containing ordered, mesoporous solid catalyst is disclosed. | 04-09-2015 |
20150059129 | PRODUCTION OF HIGH PURITY SALT WITH REDUCED LEVELS OF IMPURITIES - The invention discloses an improvement over the existing process of producing solar salt of high purity from seawater and minimizes the need for downstream purification. More particularly, the invention teaches the practical utility of recrystallization of salt in solar salt pans using seawater itself as the dissolving medium. The resultant recrystallized salt is obtained with a yield up to 80% and with much reduced levels of impurities. Special mention is made of the bromide level which is reduced 7-10 fold. The invention is most ideal for trace impurities which reside in the salt crystal lattice and are difficult to dislodge by conventional methods adopted for salt purification and where conventional recrystallization would be cost ineffective and scalability would pose a problem. The invention can be practiced by solar salt works based on seawater and where spare land is available to set up additional crystallizers required for the purpose of recrystallization. | 03-05-2015 |
20150051422 | SOLVENT FREE PROCESS FOR PURIFICATION OF FREE BIO-AMINO ACIDS - The present invention relates to a green process for purification of free bio amino acids from plant parts, particularly tea leaves and shoots. The invention more particularly relates to an organic solvent free, fast and economical process for purification of natural amino acids on large scale without using any chemical, acid or alkali substance. The invention also relates to a process for purification of bio amino acids from plant and plant parts (renewable bioresources) which are rich in free amino acids. | 02-19-2015 |
20150038714 | Process for Synthesis of Chiral 3-Substituted Tetrahydroquinoline Derivatives - The present invention relates to novel and concise process for the construction of chiral 3-substituted tetrahyroquinoline derivatives based on proline catalyzed asymmetric α-functionalization of aldehyde, followed by in situ reductive cyclization of nitro group under catalytic hydrogenation condition with high optical purities. Further the invention relates to conversion of derived chiral 3-substituted tetrahydroquinoline derivatives into therapeutic agents namely (−)-sumanirole (96% ee) and 1-[(S)-3-(di-methylamino)-3,4-dihydro-6,7-dimethoxy-quinolin-1(2H)-yl]propanone[(S)-903] (92% ee). | 02-05-2015 |
20150037466 | DOUBLE FORTIFIED SALT COMPOSITION CONTAINING IRON AND IODINE AND PROCESS FOR THE PREPARATION THEREOF - The present invention relates to stable and white iron fortification and iron+iodine double fortification agents, their preparation and use in fortification of salt. These agents help overcome the normal difficulties encountered in iron and iodine fortification such as low iodine stability on storage, development of colour and odour, and use of unwanted additives to impart stability. In one of the invented products, both iron and iodine coexist in stable manner in the same matrix which allow for a more uniform distribution of iodine. The process of preparation is demonstrated to be scalable and utilizes commonly available raw materials which would enable the products to be synthesized in affordable manner. | 02-05-2015 |
20150010448 | SELECTIVE EXTRACTION OF POTASSIUM CHLORIDE EMPLOYING TARTARIC ACID AS SAFE, BENIGN AND RECYCLABLE EXTRACTANT - Although U.S. Pat. No. 8,182,784 teaches the recovery of potassium chloride from schoenite end liquor (SEL) using dipicrylamine as extractant, and consequently simplifies the recovery of sulphate of potash (SOP) from kainite mixed salt employing the scheme disclosed in U.S. Pat. No. 7,041,268, the hazards associated with this extractant have thwarted practical utilization of the invention. Many other extractants for potash recovery have been disclosed in the prior art but none has been found suitable so far for practical exploitation. It is disclosed herein that the bitartrate ion, and particularly L-bitartrate, precipitates out potassium bitartrate very efficiently from SEL with ca. 90% utilization of the extractant. In contrast, recovery of potassium bi-tartrate from sea bittern directly is relatively much lower. It is further disclosed that this precipitate can be treated with magnesium hydroxide and magnesium chloride to throw out magnesium tartrate with ca. 90% recovery while yielding a nearly saturated solution of potassium chloride which can be utilized for the reaction with schoenite to obtain SOP. It is further demonstrated that the magnesium tartrate can be treated with an appropriate amount of aqueous HCl and added into a subsequent batch of SEL to throw out potassium bitartrate once again which demonstrates the recyclability of the extractant. The overall loss of tartrate over a cycle was ca. 20% but the dissolved tartrate remaining in the K-depleted SEL and KCl solutions can be precipitated out as calcium tartrate from which tartaric acid can be recovered by known methods, curtailing thereby the loss of tartaric acid per kg of KCl to <5 g. It is also demonstrated that through a similar approach, seaweed sap containing ca. 4% KCl can be concentrated to 20-22% KCl, with excellent utilization efficiency of tartaric acid, and this solution can similarly be utilized for SOP preparation. Potassium salts bearing other anions such as sulphate, nitrate, phosphate and carbonate can also be prepared from the isolated potassium bitartrate. | 01-08-2015 |
20140369938 | CURCUMIN COATED MAGNETITE NANOPARTICLES FOR BIOMEDICAL APPLICATIONS - The present invention discloses biocompatible, stable curcumin or its derivatives coated ultra-small super paramagnetic iron oxide nanoparticles (USPION) for biomedical applications. Disclosed herein is also a simple one-pot process for the synthesis of biocompatible, stable curcumin or its derivatives coated ultra-small superparamagnetic iron oxide nanoparticles in absence of a linker or binder. The curcumin or its derivatives coated ultra-small super paramagnetic iron oxide nanoparticles of the present invention retains the medicinal, radical scavenging and fluorescence properties of curcumin. | 12-18-2014 |
20140350271 | PROCESS FOR CHEMICAL CONVERSION OF CELLULOSE ISOLATED FROM AROMATIC SPENT BIOMASS TO HYDROXY METHYL FURFURAL - The present invention relates to a process for chemical conversion of cellulose isolated from aromatic spent biomass to hydroxymethyl furfural using an eco-friendly and economical liquids system with recoverable and reusable solid Indion catalysts and zeolite-phosphomolybdic acid hybrid catalysts. The present invention further relates to the preparation of an effective hybrid catalyst i.e. zeolite-phosphomolybdic acid catalyst for synthesis of HMF. The selectivity and yield of HMF is nearly doubled in zeolite-phosphomolybdic acid hybrid catalyst compared to the individual catalysts (zeolite or phosphomolybdic acid) or combination of catalysts viz. zeolite and phosphomolybdic acid. | 11-27-2014 |
20140348788 | METHOD TO MODULATE PIGMENTATION PROCESS IN THE MELANOCYTES OF SKIN - The invention describes a method to modulate melanosome maturation process in melanocytes. Further, it describes a method to reversibly alter the process of pigmentation in the human epidermal skin. The method targets melanosome maturation and its transfer to keratinocytes, which are key processes involved in the pigmentation for its potential use in predictable and controlled regulation of pigmentation in human skin. | 11-27-2014 |
20140329073 | SOLAR SELECTIVE COATING HAVING HIGH THERMAL STABILITY AND A PROCESS FOR THE PREPARATION THEREOF - The present invention describes an improved multilayer solar selective coating useful for solar thermal power generation. Solar selective coating of present invention essentially consists of Ti/Chrome interlayer, two absorber layers (AlTiN and AlTiON) an anti-reflection layer (AlTiO). Coating deposition process uses Ti and Al as the source materials, which are abundantly available and easy to manufacture as sputtering targets for industrial applications. The present invention allows deposition of all the layers in a single sputtering chamber on flat and tubular substrates with high absorptance and low emittance, thus making the process simpler and cost effective. The process of the present invention can be up-scaled easily for deposition on longer tubes with good uniformity and reproducibility. The coating of the present invention also displays improved adhesion, UV stability, corrosion resistance and stability under extreme environments. | 11-06-2014 |
20140315244 | NOVEL FUNGAL STRAIN BEAUVERIA SP. MTCC 5184 AND A PROCESS FOR THE PREPARATION OF ENZYMES THEREFROM - A fungal strain | 10-23-2014 |
20140309434 | SYNTHESIS OF PSUEDO INDOXYL DERIVATIVES - The patent discloses novel 2,2-disubstituted 1,2-dihydro-3H-indol-3-one derivatives and their preparation thereof. | 10-16-2014 |
20140301608 | CHEMICAL STRUCTURE RECOGNITION TOOL - A method of extracting and then reusing/remodeling chemical data from a hand written or digital input image without manual inputs using Chemical Structure Recognition Tool (CSRT) is disclosed herein. It comprises loading said input image, converting said input image into a grayscale image i.e. stretching of loaded input image, converting said grayscale image into a binary image i.e. binarisation, smoothing to reduce noise within said binary image, recognizing circle bond to identify presence of a circle inside a ring, predicting OCR region to find zones containing text, image thinning to identify specific shapes within said binary image, edge detection to detect image contrast, detecting double and triple bond, and obtaining output files. | 10-09-2014 |
20140296530 | INDOLIZINONE BASED DERIVATIVES AS POTENTIAL PHOSPHODIESTERASE 3 (PDE3) INHIBITORS AND A PROCESS FOR THE PREPARATION THEREOF - The present invention provides compounds of general formula A useful as potential phosphodiesterase3 (PDE3) inhibitory agents and a process for the preparation thereof. The derivatives of formula A can be employed as therapeutics in human and veterinary medicine, where they can be used, for example, for the treatment and prophylaxis of the following diseases: heart failure, dilated cardiomyopathy, platelet inhibitors, cancer and obstructive pulmonary diseases. | 10-02-2014 |
20140296133 | SILA ANALOGS OF OXAZOLIDINONE DERIVATIVES AND SYNTHESIS THEREOF - The invention discloses silaanalogs of oxazolidinone compounds, to pharmaceutical compositions and to the synthesis of the oxazolidinone derivatives of formula I. The invention further relates to methods of treating a subject suffering with gram positive pathogens including those resistant to methicillin and vancomycin using the compound(s) or modulation of coagulation properties of blood-clotting cascade or compositions of the oxazolidinone derivatives of the invention. | 10-02-2014 |
20140295518 | PROCESS FOR GENERATION OF HYDROGEN AND SYNGAS - The present invention is related to a process for generation of hydrogen and syngas based on biomimetic carbonation and photocatalysis. A path breaking way has been developed for generation of solar fuels in specific hydrogen by coupling biomimetic carbonation with photocatalysis. Efforts are being made worldwide to mimic the reaction for fixation of anthropogenic CO2 into calcium carbonate using carbonic anhydrase (CA) as a biocatalyst. CA is being employed to accelerate the rate of hydration of CO2 to form carbonate ions and proton. Presently carbonate is being precipitated from aqueous solution as calcium carbonate given a suitable saturation of calcium and carbonate ions by addition of appropriate buffer. A major breakthrough in the area of generation of solar fuels like hydrogen has been achieved by coupling biomimetic carbonation with photocatalysis. This approach may prove to be a revolutionary technical advancement required for hydrogen economy demanding carbon neutral hydrogen production. Also the production of hydrogen in addition to carbonates as end products during biomimetic carbonation may make the process commercially viable to be adopted by industries emitting carbon dioxide. The carbonate rich stream has been photocatalytically reduced to formaldehyde. This breakthrough thus opens new horizons in the area of carbon sequestration by virtue of the fact that end product of carbon sequestration is not only environmentally benign product of calcite but it would lead to the generation of clean energy including hydrogen, methane and methanol. Maximum hydrogen evolution has been observed up to 101.14 μmoles/mg of, free CA, 156.8 μmoles/mg of immobilised CA and 101.14 μmoles/mg of CA 6684.5 μmoles/mg of stabilised CA using TiO2/Zn/Pt as photocatalyst. The problem of using Zn as a metal donor has been overcome by illuminating the system. Hydrogen evolution to the tune of 84 μmoles/mg of CA has been observed for system with Zn as metal donor in the presence of Pt as co-catalyst with illumination. | 10-02-2014 |
20140287534 | HIGHLY SENSITIVE MAGNETIC TUNABLE HETEROJUNCTION DEVICE FOR RESISTIVE SWITCHING - The present invention discloses highly sensitive magnetic heterojunction device consisting of a composite comprising ferromagnetic (La | 09-25-2014 |
20140249194 | OPTICALLY ACTIVE FLUCONAZOLE ANALOGUES CONTAINING THIOPHENES AS ANTIFUNGAL AGENTS - The invention discloses optically active compounds of Formula (1a) or Formula (1b), | 09-04-2014 |
20140243537 | PROCESS FOR THE PREPARATION OF OSELTAMIVIR AND METHYL 3-EPI-SHIKIMATE - The present invention discloses high yielding enantioselective process for synthesis of Oseltamivir from readily available starting material, cis-1,4-butene diol. The process features incorporation of chirality using sharpless asymmetric epoxidation (AE) and diastereoselective Barbier allylation and construction of cyclohexene carboxylic acid ester core through a ring closing metathesis (RCM) reaction. Further also disclosed herein is synthesis of (−)-methyl 3-epi-shikimate. | 08-28-2014 |
20140235863 | SUBSTITUTED 4-ARYLTHIAZOLES AND PROCESS OF PREPARATION THEREOF - The present invention relates to novel substituted 4-arylthiazoles, their preparation, and to their use as therapeutic agents, particularly in the prevention or treatment of tuberculosis. The present invention particularly relates to compounds of formula A: | 08-21-2014 |
20140221651 | PYRIDOPYRIMIDINE BASED DERIVATIVES AS POTENTIAL PHOSPHODIESTERASE 3 (PDE3) INHIBITORS AND A PROCESS FOR THE PREPARATION THEREOF - The present invention provides compounds of formula 1 as potential phosphodiesterase3 (PDE3) inhibitory agents and a process for the preparation thereof. The derivatives of formula 1 can be employed as therapeutics in human and veterinary medicine, where they can be used, for the treatment and prophylaxis of the following diseases: heart failure, dilated cardiomyopathy, platelet inhibitors, cancer and obstructive pulmonary diseases. | 08-07-2014 |
20140221199 | STABLE OXIDE ENCAPSULATED METAL CLUSTERS AND NANOPARTICLES - The present invention discloses stable, non-agglomerated, ultra-small metal/alloy clusters encapsulated in silica with the metal/alloy cluster size of less than 5 nm. The invention further discloses a simple, cost effective process for the preparation of metal/alloy clusters encapsulated in silica which is thermally stable and without agglomeration. | 08-07-2014 |
20140213535 | NOVEL FLAVONOL COMPOUNDS, COMPOSITIONS THEREOF AND METHOD FOR TREATING BONE DISORDERS - Flavonol compounds, pharmaceutical compositions of the compounds and methods for treating bone disorders by administering the pharmaceutical composition by oral, intravenous, subcutaneous, intra-peritoneal or intramuscular route. | 07-31-2014 |
20140198380 | PLANAR SOLAR CONCENTRATORS USING SUBWAVELENGTH GRATINGS - Light concentration of order more than 10 times using sub-wavelength diffraction gratings integrated on top and bottom surface of a planar glass substrate is claimed. The invention discloses designing of subwavelength gratings, with period less than the wavelength of light, which can effectively guide the incoming solar radiation into the glass substrate. The subwavelength gratings so designed eliminate long wavelength IR light with energy below the band gap of solar cell completely thus reducing the heating of the solar cell and eliminating the extra cooling requirement (size) thus increasing the efficacy. The subwavelength gratings integrated on top of low cost planar glass substrates and can be used for solar photovoltaic and other applications for heating/cooling purposes. | 07-17-2014 |
20140197024 | MICROWAVE INDUCED SINGLE STEP GREEN SYNTHESIS OF SOME NOVEL 2-ARYL ALDEHYDES AND THEIR ANALOGUES - A microwave-induced process for the preparation of 2-aryl and 2,2-diaryl aldehydes and analogues wherein halohydrin formation and subsequent rearrangement to 2-aryl aldehydes from corresponding aryl alkanols occurs without formation of an intermediate epoxide or use of transition metal catalysts or lewis acids/bases. | 07-17-2014 |
20140186248 | PROCESS FOR THE ADSORPTION OF TOXIC SULPHUR BEARING GASES - The preparation of nano-oxide coated adsorbent, which is useful for treatment of toxic gases, by coating of composite materials containing hydrotalcite over ceramic monolithic substrates. Oxides and salts of metals are reacted in a known manner to prepare hydrotalcites or mixed metal layered hydroxides such as Mg—Al, Ca—Al, Zn—Al, Zn—Cr type possessing positive layer charge, from which a stable gel is prepared by adding swellable clay, e.g., montmorillonite etc. in different hydrotalcite:clay ratio in an aqueous medium and homogenising the same with high speed homogeniser and ultrasonicator in a high intensity ultrasonic processor. The gel is dip-coated over cordierite/mulite honey-comb monolithic supports. The dip-coated monoliths are dried and calcined to develop the alumino-silicate supported nano-oxide coats over honey-comb ceramic substrates for carrying out adsorption of H | 07-03-2014 |
20140183450 | CATALYST FREE SYNTHESIS OF VERTICALLY ALIGNED CNTs ON SiNW ARRAYS - The present invention discloses novel one dimensional, direct nano-heterojunctions of vertically aligned silicon nanowires (SiNW)-carbon nano tube (CNT) arrays with ultra-low turn-on field useful in single electronic devices. The invention further discloses catalyst free chemical vapor deposition (CVD) route for synthesis of one dimensional, direct nano-heterojunctions of vertically aligned SiNW-CNT arrays. | 07-03-2014 |
20140171662 | PIMARANE DITERPENES FROM ANISOCHILUS VERTICILLATUS - This invention discloses diterpenes class of novel compounds of general formula I from a novel source. More particularly the invention relates to extracts/fractions containing pimarane diterpenes from | 06-19-2014 |
20140170037 | DYE ENTRAPPED SOL-GEL FILM BASED TEST STRIP SENSOR FOR NITRITE AND A PROCESS OF PREPARING SAID STRIP SENSOR - The present invention relates to test strips that are photo and thermally stable, optically transparent and offer virtually specific absorptiometric sensing of nitrite in natural waters. The process of which is as follows: 1) The entrapment of xanthene dye specifically rhodamine 6G in sol-gel glass. This entrapment is done by delicate balance of coulombic interactions, hydrogen bonding and molecular imprinting effect. 2) In particular, rhodamine 6G entrapped sol-gel layers are formed by first preparing a sol by sonicating a mixture of tetraethoxsilane, water and ethanol for 30 minutes and hydrolysed to form gel by drop wise addition of hydrochloric acid. 3) This gel is further sonicated for 30 minutes after addition of dye and then aged for 15-20 h to obtain dye entrapped sol-gel glass and 4) This is then manually cast as sol-gel films on glass substrates to obtain test strips. | 06-19-2014 |
20140155653 | AN IMPROVED PROCESS FOR CATALYTIC DEHYDRATION OF LACTIC ACID TO ACRYLIC ACID - Disclosed herein is an improved process for the catalytic dehydration of lactic acid to acrylic acid. More particularly, the present invention discloses catalytic dehydration of lactic acid to acrylic acid with high selectivity and yield for acrylic acid using calcium phosphate (CP) catalyst with varying Ca/P ratio optionally modified with 5 wt % sodium. | 06-05-2014 |
20140145117 | COKE RESISTANT SOLID CATALYST, PROCESS FOR THE PREPARATION THEREOF AND A PROCESS FOR VAPOUR PHASE DRY REFORMING OF METHANE - The present invention provides a coke resistant catalyst and process for sequestration of carbon dioxide via reforming of methane to synthesis gas (a mixture of CO and H | 05-29-2014 |
20140135393 | SUBSTITUTED CATHECHOLS AS INHIBITORS OF IL-4 AND IL-5 FOR THE TREATMENT BRONCHIAL ASTHMA - The present invention relates to compounds of general formula 1 for the treatment of bronchial asthma by inhibition of IL-4 or IL-5 pathway inhibition. The present invention also relates to the use of compound of general formula 1 for the treatment of bronchial by inhibition of IL-4 or IL-5 pathway. The present invention also relates to the method of treating asthma by inhibition of IL-4 or IL-5 pathway by administration of compound or said composition through oral, intranasal, route or by inhalation to a mammal in need thereof. Compound of general formula 1 may be used for reducing perivascular and peribronchial inflammation. | 05-15-2014 |
20140134395 | LACED COMPOSITE SYSTEM - The present invention relates to a laced composite system with high rotational capacity and ductility which resists the suddenly applied dynamic loads by undergoing excessive plastic deformation, while still maintaining the integrity of the system. The laced composite system comprising, a sandwiched filler material between upper and lower cover plates ( | 05-15-2014 |
20140128653 | Catalyst for Selective Dehydrogenation / Oxidative Dehydrogenation Reactions and Process for the Preparation Thereof - The present invention provides a process and catalyst for the direct and selective conversion of ethane to ethylene. The process provides a direct single step vapor phase selective dehydrogenation/oxidative dehydrogenation of ethane to ethylene over Mo supported nanocrystalline TiO | 05-08-2014 |
20140128632 | CATALYST FOR SINGLE STEP CONVERSION OF GLYCEROL TO ACRYLIC ACID AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides a process and a solid catalyst for oxydehydration of glycerol to acrylic acid with H | 05-08-2014 |
20140127397 | PROCESS FOR THE PREPARATION OF KISH GRAPHITIC LITHIUM-INSERTION ANODE MATERIALS FOR LITHIUM-ION BATTERIES - The present invention provides a process for the production of high-capacity kish graphitic lithium-insertion anode materials and negative electrodes prepared therefrom for lithium-ion batteries. The graphitic materials are produced by precipitating excess carbon present in supersaturated solutions of carbon in iron/steel uninoculated or inoculated with metals/metalloid singly or in combination. The form of carbon used for dissolution is a carbon-containing polymeric precursor such as biomaterials and non-biodegradable plastic wastes, the carbonization of which can be carried out in situ or prior to addition in the melt. The graphitic products deliver reversible capacities between 300 and 600 mAh·g−1 with flat voltage profiles for electrochemical insertion/deinsertion of lithium at potentials less than 200 mV. | 05-08-2014 |
20140099684 | ENGINE WORTHY FATTY ACID METHYL ESTER (BIODIESEL) FROM NATURALLY OCCURING MARINE MICROALGAL MATS AND MARINE MICROALGAE CULTURED IN OPEN SALT PANS TOGETHER WITH VALUE ADDITION OF CO-PRODUCTS - The invention teaches the obtained specifications and process of production of engine worthy marine microalgal fatty acid methyl ester (biodiesel) using naturally occurring marine microalgal mats and also marine microalgae cultivated in cost-effective manner in solar salt pans. Utility of co-product streams adds to the attractiveness of the invention. | 04-10-2014 |
20140093456 | TUMOR MODEL SYSTEM USEFUL TO STUDY MULTISTAGE CANCER - The present invention relates to a method of developing a Tumor Model System. The invention deals with a tumor model system with adhesion deprived cells. This observation provides a new method for primary detection of transformation of adhesion-deprived cells and tumorigenicity. The adhesion-deprived cells are capable of metastasizing at distant sites and the model system includes both the tumor formation and metastasis. | 04-03-2014 |
20140087257 | CATHODE MATERIAL AND LITHIUM ION BATTERY THEREFROM - A new high performing lithium ion cell having new carbon based anode and new dual doped layered cathode materials. The anode is a self standing carbon fibrous material and the cathode is a dual doped Lithium cobalt oxide of general formula LiM | 03-27-2014 |
20140081063 | CATALYST AND PROCESS FOR THE CONVERSION OF BIO-ETHANOL INTO GASOLINE - In an attempt to conduct an effective conversion of bioethanol into gasoline rich in aromatics and iso-paraffins, a ZSM-5 type zeolite with special features such as nano crystalline size and acidity has been synthesized. The catalyst (NZ) exhibits highest gasoline yield of about 73.8 wt % with aromatics and iso-paraffins as major components. The product measures Research Octane Number (RON) of about 95, which is desirable for the gasoline specifications. Moreover, considerable amounts of the Liquefied Petroleum Gas (LPG) (15 wt %) and light olefins (14 wt %) are also formed as by-products that add value to the process. The nano crystalline ZSM-5 catalyst (NZ) exhibits the stability in activity in terms of bioethanol conversion and aromatics yields for the reaction time period of 40 h. | 03-20-2014 |
20140080184 | NOVEL ISOLATED BACTERIAL STRAIN OF GLUCONACETOBACTER OBOEDIENS AND AN OPTIMIZED ECONOMIC PROCESS FOR MICROBIAL CELLULOSE PRODUCTION THEREFROM - The present invention provides a novel and potent cellulose producing bacterial species, | 03-20-2014 |
20140079834 | BIOACTIVE FRACTIONS AND COMPOUNDS FROM DALBERGIA SISSOO FOR THE PREVENTION OR TREATMENT OF OSTEO-HEALTH RELATED DISORDERS - The present invention relates to bioactive fractions and compounds from | 03-20-2014 |
20140069327 | PROCESS FOR DEVELOPING A COMPOSITE COATING OF DIAMOND LIKE CARBON AND GRAPHITE ON SILICON CARBIDE GRAIN BY INDIRECT ARC PLASMA HEATING DISSOCIATION - The present invention relates to a process for in situ growth of carbonaceous composite coating of diamond like carbon (DLC) and graphite on silicon carbide (SiC) grains by carrying out thermal dissociation of SiC by an indirect arc plasma heating and the said process comprising the steps of: (i) providing SiC grains in a graphite crucible; (ii) passing inert gas in the arc zone situated below the graphite crucible; (iii) passing a inert gas inside the graphite crucible; (iv) heating the graphite crucible by arc plasma for a period in the range of 15 to 30 minutes; (v) continuing the inert gas flow in arc zone and in graphite crucible for 50 to 70 minutes; (vi) cooling the reactor to obtain a carbonaceous composite coating having diamond like carbon (DLC) and graphite on silicon carbide (SiC) grains. | 03-13-2014 |
20140057778 | SULFONATED CARBON SILICA COMPOSITE MATERIAL AND A PROCESS FOR THE PREPARATION THEREOF - The present invention relates to a novel sulfonated carbon silica (SCS) composite material and a process for the preparation thereof. The synthesized SCS composite material on calcination yields the hierarchical mesoporous silica (MS) and further finds application as catalyst in two industrially important reactions namely phenol butylation and glycerol acetalization. | 02-27-2014 |
20140046090 | PROCESS FOR CONTINOUS FLOW SYNTHESIS OF beta-AMINO CROTONATE - Beta aminocrotonates are important intermediates for the synthesis of Ca channel blockers. The processes available in the art are batch processes with yields about 85%. There are no continuous processes available for the synthesis of such compounds. This gap in the art is addressed by the invention by disclosing a continuous process resulting in high yields of beta amino crotonates. | 02-13-2014 |
20140038879 | SURFACE INDUCED DISASSEMBLY OF NANO CONTAINERS - The invention discloses composition of oxidized conducting polymer and micelle assembly for site specific delivery of guest molecule. This delivery is achieved by by polyvalent interaction between micelle assemblies and delocalized charges of polymer to trigger the disassembly. The invention further discloses the process of preparation of composition of oxidized conducting polymer and micelle assembly for site specific delivery of guest molecule. | 02-06-2014 |
20140038249 | Integrated Process For The Production Of Jatropha Methyl Ester And By Products - The present invention provides a simpler and more energy efficient process for the preparation of fatty acid methyl ester (biodiesel) from sun dried whole seed capsules of | 02-06-2014 |
20140030709 | Biomarker for Detecting High-Altitude Adaptation and High-Altitude Pulmonary Edema - Present invention relates to the Biomarkers for detecting high altitude adaptation and hypoxia responsiveness and the method thereof. The invention specifically relates to the Gene variants SNPIDs rs479200 and rs480902 in the first intron of EGLN1 (Prolyl Hydroxylase 2) gene as biomarkers for adaptation to high altitude and predisposition for high altitude pulmonary edema and hypoxia responsiveness using a novel integrative approach of phenotyping concepts of Ayurveda with population genetics, and disease genomics. More specifically, the C allele of SNP ID rs480902 and T allele of rs479200 of EGLN1 gene is more frequent in patients of HAPE and nearly absent in native highlanders. The present invention also provides primers and methods suitable for the detection of these allelic variants for the prediction of individual's adaptability to high altitude and hypoxia and/or the genetic analysis of the EGLN1 gene in a population. | 01-30-2014 |
20140026787 | COMPOSITION FOR ADVANCED HYBRID GEOPOLYMERIC FUNCTIONAL MATERIALS AND A PROCESS FOR THE PREPARATION THEREOF - The present invention provides a composition for advanced hybrid geopolymeric functional materials possessing very broad application spectrum ranging from cementitious materials to advanced functional materials having “Inorganic-Organic Hybrid” matrix in contrast to the limited application of conventional geopolymeric materials having “Inorganic matrix” only. The invention further relates to a process for the preparation of these materials. The process obviates the need of external addition of sodium silicate which is one of the costliest and main raw materials in conventional geopolymerisation processes. Interestingly, in the present invention the sodium silicate has been synthesized in situ by designing of conditions for synergistic and simultaneous mechano-chemical reactions among the selected raw materials viz. inorganic and organic wastes under alkaline environment. This results in the formation of “Hybrid inorganic-organic frame work” of sodium silicate, which facilitates uniform dispersion of reacting species, thus resulting in the formation of homogeneous geopolymeric matrix with improved characteristics. | 01-30-2014 |
20140023883 | CARBAZOLE END CAPPED BIPYRIDINE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF - The present invention is to provide highly solid state emissive fluorophores of the formula 1 and 2 useful for the solid state lighting. The formula 1 and 2 have good solid state emission in blue and green region respectively. The zinc complexes of formula 1A and 2A have yellow and red emission respectively in solid state. The present invention also provide high solid state emissive assay of formula 1 and 2 to convert UV light into visible light by coating the color tunable materials on the 365-nm emitting solid state LED. The present invention further provides carbazole end-capped bipyridine for screening of metal salts with different counterions in solutions. The discrimination of the various metal salts can be monitored by noting the fluorescence change in solution. The zinc salts with different counterions have different emission color in solution. The present invention also develop a new two photon active fluorescent Zn | 01-23-2014 |
20140018238 | ACTIVATED CARBON-METAL ORGANIC FRAMEWORK COMPOSITE MATERIALS WITH ENHANCED GAS ADSORPTION CAPACITY AND PROCESS FOR THE PREPARATION THEREOF - The present invention discloses activated carbon-metal organic framework composite materials (AC@MOF) with enhanced gas adsorption capacity. The present invention also discloses a process for the preparation of carbon-metal organic framework composite materials (AC@MOF). The present invention involves the use of “void space filling method” in metal organic frameworks (MOFs), which have been accomplished by in-situ addition of selected type and appropriate amount of activated carbon during the synthesis of MOF such as Cu-BTC, in the storage of gases such as methane. The gas adsorption capacity of these AC@MOF composite materials is significantly increased through this method. | 01-16-2014 |
20140017595 | PROCESS FOR THE PREPARATION OF MEMBRANE ELECTRODE ASSEMBLIES (MEAs) - PBI-based MEAs for high temperature Polymer Electrolyte Membrane Fuel Cell (PEMFC) were prepared by direct hot pressing of catalyst layer on Teflon sheets on to both sides of phosphoric acid doped PBI membrane (decal transfer). These MEAs show two times higher performance compared to the MEAs prepared by normal brush coating method on GDL at an operating temperature of 160° C. | 01-16-2014 |
20140012044 | PROCESS FOR THE SYNTHESIS OF ANTIEPILEPTIC DRUG LACOSAMIDE - The present invention relates to the improved and efficient process for the synthesis of antiepileptic drug Lacosamide in high enantiopurity (>98% ee) and better yield. More particularly, the present invention relates to improved and efficient, cost effective process for synthesis of desired (R) isomer of Lacosamide starting from commercially available (S)-benzyl glycidyl ether. | 01-09-2014 |
20140011818 | ENANTIOMERS OF FLUCONAZOLE ANALOGUES CONTAINING THIENO-[2,-3-D]PYRIMIDIN-4(3H)-ONE MOIETY AS ANTIFUNGAL AGENTS - The present invention discloses novel enantiomeric antifungal compounds of Formula (1a) and Formula (1b) containing thieno-[2,3-d]Jpyrimidin-4(3H)-one moiety and pharmaceutically acceptable salts thereof, method of preparing these compounds, the use of these compounds in prevention and treatment of fungal infections, and pharmaceutical preparations containing these compounds. | 01-09-2014 |
20140005121 | OLIGOPEPTIDES AND PROCESS FOR PREPARATION THEREOF | 01-02-2014 |
20130345454 | A PROCESS FOR THE PREPARATION OF PHYTOSTERYL FERULATE - The present invention relates to a synthetic method for the preparation of phytosteryl ferulate using ferulic acid and phytosterols (isolated from soybean oil deodorizer distillate) comprising of (a) acetylation of ferulic acid to ferulic acid acetate; (b) esterification of ferulic acid acetate with phytosterols to obtain phytosteryl ferulate acetate; (c) deprotection of phytosteryl ferulate acetate to phytosteryl ferulate. The phytosteryl ferulate was evaluated for hypocholesteremic activity in hamsters in comparison with that of natural oryzanol isolated from rice bran oil soap stock. This study confirmed that the phytosteryl ferulate significantly lowers the elevated cholesterol levels and also interferes with the absorption of cholesterol and the effect is comparable with that of natural oryzanol and is useful as nutraceutical/food supplement. Hence phytosteryl ferulate is a potential substitute for natural oryzanol for several applications. | 12-26-2013 |
20130338193 | CHIRAL 1-(4-METHYLPHENYLMETHYL)-5-OXO--PYRROLIDINE-2-CARBOXAMIDES AS INHIBITORS OF COLLAGEN INDUCED PLATELET ACTIVATION AND ADHESION - Chiral 1-(4-methylphenylmethyl)-5-oxo-{N-[(3-t-butoxycarbonyl-aminomethyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamides as inhibitors of collagen induced platelet activation and adhesion The present invention provides chiral (2S)-1-(4-methyl-phenylmethyl)-5-oxo-(3S)-{N-[(3-t butoxycarbonyl aminomethyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamide, and (2S)-1-(4-methylphenylmethyl)-5-oxo-(3R)-{N-[(3-t-butoxycarbonyl amino methyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamide of formula 6 and 7 respectively. The present invention also relates to use of these moieties as inhibitors of collagen induced platelet adhesion and aggregation mediated through collagen receptors. The present invention provides a process for preparation of chiral carboxamides of formula 6 and 7 using the process which has advantage to avoid any racemization at the a-carboxylic center, during N-alkylation. The reagent LiHMDS is used at low temperatures to furnish methyl N-(p methylphenylmethyl)lpyroglutamate in good chiral purity. | 12-19-2013 |
20130331596 | PROCESS FOR THE ECO-FRIENDLY PREPARATION OF 3, 5-DIBROMO-4-HYDROXYBENZONITRILE - A highly pure 3,5-dibromo-4-hydroxybenzonitrile (bromoxynil) has been prepared in high yield from 4-hydroxybenzonitrile using eco-friendly brominating reagent comprising of 2:1 mole ratio of bromide to bromate salts in aqueous acidic medium without any catalyst under ambient conditions with no work up procedure. The product 3,5-dibromo-4-hydroxybenzonitrile was obtained in 91-99% yield with melting point 189-191° C. and more than 99% purity by gas chromatographic analysis without any purification. | 12-12-2013 |
20130331581 | 1,2,3-TRIAZOLE CONTAINING ARTEMISININ COMPOUNDS AND PROCESS FOR PREPARATION THEREOF - The present invention relates to 1,2,3-triazole containing artemisinin compounds and process for preparation thereof. Described herein is the synthesis, bioassay results and usefulness of the artemisinin derived compounds resulting from 1,3-di-polar cycloaddition reaction of artemisinin derived azide or alkyne with aliphatic or aromatic diazides. These 1,2,3-triazole containing artemisinin derived compounds embodied in this document are found to be active against various cancer cell-lines. | 12-12-2013 |
20130331542 | PROCESS FOR PREPARING HYPERBRANCHED POLYESTERS - An efficient, eco-friendly, solvent-free process for preparing hyperbranched polyesters by reacting polyols with polycarboxylic acid in the presence of heterogeneous, reusable, acid, crystalline, micro-mesoporous double-metal cyanide catalyst at moderate temperatures and short period of reaction time. | 12-12-2013 |
20130331467 | PROCESS FOR THE MODIFICATION OF CURCUMA AROMATICA ESSENTIAL OIL - essential oil is blue-black dark liquid with camphoraceous, woody, amber and spicy characteristic odour and is less valued in market, however the prepared value added products have very good shining color with the improved fragrance. The present invention relates to an efficient process for the modification of | 12-12-2013 |
20130324679 | PERYLENEBISIMIDE-POLYESTER BLEND - The present invention provides a perylenebisimide-polyester blend and a chemical blending process for the preparation thereof. The perylenebisimide-polyester blend prepared is useful in organic light emitting diodes, solar cells and such other photovoltaic applications. | 12-05-2013 |
20130324673 | PROCESS FOR THE REMOVAL OF ARSENIC AND CHROMIUM FROM WATER - The present invention provides low cost and highly effective method for the removal of arsenic and Cr(III&VI) from contaminated water using zinc peroxide nanoparticles (20±5 nm) capped with glycerol/PVP/TEA up to the permissible range of drinking water. As Arsenic and chromium occurs naturally in the earth's crust. When rocks, minerals, and soil erode, they release arsenic and chromium into groundwater. Arsenic and chromium occurs naturally in varying amounts in groundwater in various parts of country from ppb level to ppm level. The average concentration of arsenic and chromium as per USEPA standard in drinking water it is 10 parts per billion and 0.05 ppm (50 ppb) respectively. In drinking water the level of chromium is usually low as well, but contaminated water may contain the dangerous Cr(III&VI). Although Cr(III) is an essential nutrient for humans and shortages may cause heart problems, disruptions of metabolisms and diabetes. But the uptake of too much Cr(III) can cause health effects as well, for instance skin rashes. Cr(VI) is known to cause various health effects Skin rashes, upset stomachs, respiratory problems, weakened immune systems, kidney and liver damage and lung cancer The persons who are drinking water having up to 50 ppb of arsenic and 0.05 ppm chromium over for many years could experience skin damage or problems with their circulatory system, and may have an increased risk of getting cancer. Keeping the above facts we developed a cost effective nanoparticles for the removal of Arsenic and Cr(III&VI) from potable water up to potable range. | 12-05-2013 |
20130324573 | SUBSTITUTED 1, 2, 3, 4-TETRAHYDROQUINOLIN-7-YL CARBAMATES AS ACETYLCHOLINESTERASE INHIBITORS FOR TREATMENT OF ALZHEIMER'S DISEASE - The present invention relates to novel substituted 1,2,3,4-tetrahydroquinolin-7-yl carbamates, their preparation, and use as therapeutic agents, particularly in the prevention or treatment of neurodegenerative or Alzheimer's disease, or senile dementia, or memory disturbances, and more particularly to the prevention, treatment and amelioration of Alzheimer's disease with the novel substituted 1,2,3,4-tetrahydroquinolin-7-yl carbamates, which act as inhibitors of central cholinesterase enzymes, particularly acetylcholinesterase (AChE) following the indirect cholinomimetic pathway. The present invention particularly relates to compounds of formula A: Formula A wherein R | 12-05-2013 |
20130317244 | ORGANIC-INORGANIC HYBRID CHIRAL SORBENT AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides an organic-inorganic hybrid chiral sorbent for chiral resolution of various racemic compounds viz. racemic mandelic acid, 2-phenyl propionic acid, diethyl tartrate, 2,2′-dihydroxy-1,1′-binaphthalene (BINOL) and cyano chromene oxide with excellent chiral separation (enantiomeric excess, 99%) in case of mandelic acid under medium pressure column chromatography. These optically pure enantiomers find applications as intermediates in pharmaceutical industries. | 11-28-2013 |
20130317221 | 3-ARYLETHYNYL SUBSTITUTED QUINAZOLINONE COMPOUNDS - The present invention provides 3-arylethynyl substituted quinazolinone compounds of formula (A) as potential anticancer agents against sixty human cancer cell lines. R | 11-28-2013 |
20130317211 | Pyrrolo[2,1-c][1,4]naphthodiazepine Linked Piperazine Compounds and a Process for the Preparation Thereof - The present invention provides a compound of general formula A, useful as potential antitumour agents against five human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]naphthodiazepine linked substituted piperazine conjugates attached through different alkane spacers of general formula A. (Formula I) General formula A. Where R=R′=(Formula II). n=1-9 and R″=methyl, ethyl, acetyl, benzyl, piperinoyl, 4-fluorophenyl, 4-chlorophenyl, 4-methoxyphenyl, pyridyl, pyrimidyl | 11-28-2013 |
20130315805 | Process For Simultaneous Production Of Potassium Sulphate, Ammonium Sulfate, Magnesium Hydroxide And/Or Magnesium Oxide From Kainite Mixed Salt And Ammonia - The present invention provides an integrated process for the recovery of sulphate of potash (SOP), ammonium sulphate and surface modified magnesium hydroxide and/or magnesium oxide utilizing kainite mixed salt and ammonia as the only consumable raw materials. The process involves treating kainite mixed salt with water to obtain solid schoenite and a schoenite end liquor. The latter is desulphated using CaCl | 11-28-2013 |
20130310279 | NOVEL METHOD FOR SIMULTANEOUS DETECTION AND DISCRIMINATION OF BACTERIAL, FUNGAL, PARASITIC AND VIRAL INFECTIONS OF EYE AND CENTRAL NERVOUS SYSTEM - The present invention relates to the diagnostic methods for identification of the single causative agent or more than one causative agent of ocular and nervous system infections among many probable pathogens, which can cause the infection. All the pathogens affecting a discrete area of eye or nervous system generally cause same clinical manifestations or syndromes. The present invention relates to detection and discrimination of the pathogen among the set of probable pathogens in a single test without resorting to a battery of tests each being directed at detection of one pathogen. The current invention aims at the syndrome based diagnostic replacing the diagnostics based on detection of individual | 11-21-2013 |
20130306485 | Molecularly Imprinted Conducting Polymer Film Based Aqueous Amino Acid Sensors - Molecularly imprinted conducting polymer (MICP) films were electro-polymerized on glassy carbon electrode having specific recognition sites for amino acid viz. L-tyrosine and/or L-cysteine. The amino acid templates in various imprinted films were ejected out by over-oxidation followed by washing and stabilization. Again, the template leached MICP films were modified with metal oxides [oxides of Cu | 11-21-2013 |
20130303579 | HYBRID MOLECULES CONTAINING PHARMACOPHORES OF FLUCONAZOLE AS ANTIFUNGAL AGENTS AND THEIR PREPARATION - Disclosed herein are novel antifungal compounds of Formula 1, containing fluconazole pharmacophore moieties coupled with other moieties including aryl enones and chalcones and pharmaceutically acceptable salts thereof, methods for preparing these compounds and pharmaceutical preparations containing these novel compounds for prevention and treatment of fungal infections. | 11-14-2013 |
20130289266 | Spiroannulated Nucleosides and Process for the Preparation Thereof - We claim a simple strategy for the synthesis of a collection of C(3′)-spirodihydroisobenzo- furannulated and C(3′)-spirodihydroisobenzo-furannulated nucleosides featuring a [2+2+2]-cyclotrimerization as the key reaction. The cyclotrimerization reactions are facile with the unprotected nucleosides having a diyne unit. When both alkynes of the diyne are terminal, the regioselectivity is poor. However, when one of the terminal alkynes is additionally substituted, the cyclotrimerizations are highly diaste reoselective. Since the key bicycloannulation is the final step, this strategy provides flexibility in terms of the alkynes and is thus amenable for the synthesis of a focussed small molecule library. | 10-31-2013 |
20130280707 | TOP2A INHIBITION BY TEMOZOLOMIDE AND ITS PREDICTIVE VALUE OF GBM PATIENTS SURVIVAL - The present invention provides a TOP2A inhibition by temozolomide useful for predicting glioblastoma patient's survival. Glioblastoma (GBM) is the most common, malignant primary adult brain tumor. The conventional treatments for GBM, include surgery, radiation, and chemotherapy which have only modestly improved patient survival. The patients with GBM expressing higher TOP2A transcript levels had better prognosis. More interestingly, the present invention reports that temozolomide is an inhibitor of TOP2A activity in vitro. The present invention further shows that siRNA knock down of TOP2A rendered a glioma cell line resistant to temozolomide chemotherapy. Thus it is demonstrated for the first time that temozolomide is a TOP2A inhibitor and establishes that TOP2A transcript levels determines the chemosensitivity of glioblastoma to temozolomide therapy thus explaining the very high levels of TOP2A transcript being a good prognostic indicator in GBM patients receiving temozolomide chemotherapy. | 10-24-2013 |
20130277619 | PROCESS FOR THE PREPARATION OF HIGH VOLTAGE NANO COMPOSITE CATHODE (4.9vV) FOR LITHIUM ION BATTERIES - An olivine structured nano-composite LiM | 10-24-2013 |
20130266941 | DIAGNOSTIC ASSAYS FOR THE DETECTION AND IDENTIFICATION OF ASPERGILLI - Three important species of | 10-10-2013 |
20130253093 | ADHESIVE COMPOSITION AND USES THEREOF - Disclosed herein is an adhesive composition for clutch disc application comprising of an epoxy resin of bisphenol A and epichlotrohydrin, partially hydrogenated carboxylated nitrile butadiene rubber (HX-NBR) in solid form as a toughening agent in the ratio 80:20, and optionally with additives to obtain improved lap shear strength and cushioning properties. | 09-26-2013 |
20130245048 | 4-AZA-2, 3-DIDEHYDROPODOPHYLLOTOXIN COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides 4-Aza-2,3-didehydropodophyllotoxin compound of general formula A (4a-4z and 4aa-4ae) as useful potential antitumour agents against human cancer cell lines. The present invention further provides a process for the synthesis of 4-Aza-2,3-didehydropodophyllotoxin compounds (4a-4z and 4aa-4ae). | 09-19-2013 |
20130213875 | HIGH FLUX HOLLOW FIBER ULTRAFILTRATION MEMBRANES AND PROCESS FOR THE PREPARATION THEREOF - The present invention relates to the production of high flux hollow fiber ultrafiltration membrane prepared from poly(acrylonitrile-co-methacrylic acid), (polysulfone and poly(acrylonitrile-co-methacrylic acid)) and (polysulfone and ion exchange resin (sulfonated polystyrene-divinyl benzene copolymer)) blend and the point-of-use filtration unit there from for water purification and disinfection. The produced membrane has an active layer with pore size which effectively rejects pathogens and other bacteria from contaminated water while allowing the passage of water to produce biologically pure water for drinking. Therefore, the present invention relates to development of hollow fiber ultrafiltration membrane that delivers biologically pure water at a desirable rate, that is at a rate 25-200 liters/m2.h. The membrane performance in terms of flux and rejection efficiency is dependent on polymer material type and surface properties. The hollow fiber membrane with interpenetrated structure prepared from a blend of polysulfone and a copolymer of acrylonitrile and methacrylic acid is advantageous over the membranes made either from polysulfone or the copolymer alone in terms of durability, strength, elasticity, smoothness, flux, separation efficiency, fouling resistance properties. The surface modified blend membranes with acid groups which have smaller pore size and surface charge exhibit further improvement in the separation efficiency. Using the hollow fiber membranes a point-of-use water filtration unit which is simple, compact, inexpensive device that does not require electricity has been developed to produce 150-300 ml/min product water when attached to a tab from overhead tank of about 3 meter height. | 08-22-2013 |
20130210909 | COUMARIN-CHALCONES AS ANTICANCER AGENTS - The present invention relates to certain coumarin/chalcone compounds or a pharmaceutically acceptable salt thereof. The present invention particularly relates to the coumarin/chalcone compounds as anticancer agents useful for the treatment of cancer. The present invention also relates to the process of preparation of the said compounds. | 08-15-2013 |
20130208560 | FRACTAL IMPELLER FOR STIRRING - A fractal impeller design for stirred tank reactors comprising plurality of main branches, each of which further having plurality of sub-branches with each sub branch having plurality of blades to distribute/dissipate energy in uniform manner and to achieve uniform temperature throughout the reactor while operating it at lower impeller speed to avoid high shear zones; wherein, the angular distances covered by the blades vary and yield variation in the local blade passage velocity for a given impeller rotation speed. | 08-15-2013 |
20130197052 | TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY - The synthesis and evaluation of gastroprotective effect of different tryptamine derivatives. Tryptamine derivatives have been synthesized by formation of amide or ester with some known anti oxidant molecules. These derivatives show excellent antioxidant property in vitro. Among all the derivatives the compound SEGA (3a), that was prepared by the combination of serotonin with gallic acid shows the greater antioxidant property than the other synthesized compounds both in vivo and in vitro. SEGA(3a) shows the gastroprotective effect against NSAIDs (indomethacin or diclofenac)-induced gastropathy in dose dependent manner and also accelerates the healing from injury. It prevents the NSAIDs-induced mitochondrial oxidative stress in vivo. This derivative prevents NSAID-induced mitochondrial oxidative stress-mediated apoptosis in vivo by preventing the activation of caspase 9 and caspase-3 and restores NSAIDs-mediated collapse of mitochondroial transmembrane potential and dehydrogenase activity. SEGA (3a) plays an important role as an iron chelator as well as intra mitochondrial ROS scavenger. Thus, SEGA (3a) is a potent antioxidant antiapototic molecule, which efficiently prevents NSAID-induced gastropathy and stress or alcohol-mediated gastric damage. | 08-01-2013 |
20130184462 | METHOD FOR PREDICTING AND MODELING ANTI-PSYCHOTIC ACTIVITY USING VIRTUAL SCREENING MODEL - The present invention relates to the development of a virtual screening model for predicting antipsychotic activity using quantitative structure activity relationship (QSAR), molecular docking, oral bioavailability, ADME and Toxicity studies. The present invention also relates to the development of QSAR model using forward stepwise method of multiple linear regression with leave-one-out validation approach. QSAR model showed activity-descriptors relationship correlating measure (r | 07-18-2013 |
20130184412 | QUATERNISED POLYBENZIMIDAZOLE - The invention discloses polymeric forms of ionic liquids, PFILs, based on polybenzimidazole (PBI) and a process for the synthesis of such polymeric forms of ionic liquids. The invention also relates to use of PBI based polymeric forms of ionic liquids and their membranes for gas sorption, permeation and separation. | 07-18-2013 |
20130183377 | SYNTHETIC IMMUNOGEN USEFUL FOR GENERATING LONG LASTING IMMUNITY AND PROTECTION AGAINST PATHOGENS - The present invention relates to a synthetic immunogen represented by the general formula 1, useful for generating long lasting protective immunity against various intracellular pathogens which are the causative agents of tuberculosis, leishmaniasis, AIDS, trypanosomiasis, malaria and also allergy, cancer and a process for the preparation thereof. The developed immunogen is able to circumvent HLA restriction in humans and livestock. The invention further relates to a vaccine comprising the said immunogen for generating enduring protective immunity against various diseases. The said vaccine is targeted against intracellular pathogens, more particularly the pathogen | 07-18-2013 |
20130175182 | ELECTROCHEMICAL PROCESS FOR SYNTHESIS OF GRAPHENE - A process for the transformation of carbon nanotubes (CNTs) to nanoribbons composed of a few layers of graphene by a two-step electrochemical approach is disclosed in this invention. This consists of the oxidation of CNTs at controlled potential, followed by reduction to form graphene nanoribbons (GNRs) having smooth edges and fewer defects, as evidenced by multiple characterization techniques, including Raman spectroscopy, atomic force micro-scopy, and transmission electron microscopy. This type of ‘unzipping” of CNTs (single-walled, multi-walled) in the presence of an interfacial electric field provides unique advantages with respect to the orientation of CNTs, which might make possible the production of GNRs with controlled widths and fewer defects. The extent of oxidation was confirmed by various characterization techniques like XRD, XPS and Raman spectroscopy. In the second step of experiments, the CNT oxide were reduced for different periods such as 4, 8, 12 hours at fixed negative potentials of −0.5 V, so as to get layers of graphene ribbons as tabulated herein. | 07-11-2013 |
20130164799 | Integrated Process for the Production of Oil Bearing Chlorella Variabilis for Lipid Extraction Utilizing by Products of Jatropha Methyl Ester (JME) Production - An energy efficient process for the preparation of marine microalgae | 06-27-2013 |
20130137895 | METHOD FOR THE EXTRACTION OF SHIKIMIC ACID - This invention is directed to the production of shikimic acid from | 05-30-2013 |
20130136731 | Protein Fusion Constructs Possessing Thrombolytic and Anticoagulant Properties - The present invention discloses novel hybrid proteins that have both plasminogen activator and anti-thrombotic properties, including clot specific action, that renders these as highly advantageous for the treatment of circulatory disorders involving fibrin clot formation due to underlying tissue damage in the blood vessels leading to myocardial infarction, strokes etc. Also disclosed are new proteins, and methods of obtaining the same, that help to dissolve blood clots by activating plasminogen in a plasmin or thrombin dependent manner and also inhibit both the activity and generation of thrombin through the intrinsic pathway of blood coagulation. | 05-30-2013 |
20130131350 | PYRIDIN-2YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF - The present invention relates to Pyridin-2-yl sulfanyl acid ester compounds having antiinflammatory properties. The present invention particularly relates to novel anti-inflammatory heterocyclic acid esters of Pyridin-2-yl sulfanyl having the structure of general formula 1 which have been screened for their antiinflammatory activity with respect to inhibition of adhesion of neutrophils, isolated from human peripheral blood, onto the surface of human umbilical vein endothelial cells (HU-VEC) as a result of inhibition of the cytokine-stimulated expression of cell adhesion molecule ICAM-1. The compound RS—Z, 3-(Pyridin-2-yl sulfanyl)-propionic acid pentyl ester (structure 1a, R | 05-23-2013 |
20130130306 | ZN (II) BASED COLORIMETRIC SENSOR AND PROCESS FOR THE PREPARATION THEREOF - A colorimetric chemosensor molecule having a aza-macrocycle Zn (II)-complex (L.Zn) (Scheme 1, Formula 1A) which can recognize selectively and efficiently ATP (Adenosine triphosphate), a biologically significant triphosphate in aqueous medium at pH 7.4 is described. Since ATP is the source of energy in living organisms, L.Zn (Scheme 1, Formula 1A) can also be used as a staining agent in the living cells through binding to ATP, generated in situ during the metabolic process. | 05-23-2013 |
20130129758 | NOVEL CATIONIC AMPHIPHILES WITH MANNOSE-MIMICKING HEAD-GROUPS AND A PROCESS FOR THE PREPARATION THEREOF - The present invention discloses novel cationic amphiphiles containing mannose-mimicking shikimic and quinic acid head-groups and a process for preparing cationic amphiphiles with mannose-mimicking polar head-groups such as, shikimic and quinic acids. The findings described herein also demonstrate that compounds of the present invention can target model DNA vaccines to antigen presenting cells (APCs) such as macrophages and dendritic cells (DCs), via mannose receptors expressed on the cell surface of APCs. The cationic amphiphiles disclosed herein show enhanced cellular and humoral immune response compared to their mannosyl counterpart in dendritic cell (DC, the most professional APC) based genetic immunization in mice. Cationic amphiphiles with mannose-mimicking quinic and shikimic acid head-groups described in the present invention are likely to find future applications in the field of genetic immunization. | 05-23-2013 |
20130129610 | HYDROGEN/SYNGAS GENERATOR - The present invention relates to a compact, concentric auto thermal hydrogen/syngas generator for production of hydrogen/syngas without any external heating. Further, the auto thermal hydrogen/syngas generator of the present invention involves combination of reactions such as partial oxidation, steam reforming, dry reforming, auto thermal reforming, dry autothermal reforming, water gas shift, preferential oxidation or methanation that takes place without external heating, for converting air, steam and fuel into a reformate mainly containing CO, CO | 05-23-2013 |
20130123555 | Modified Zeolite Catalyst Useful for the Conversion of Paraffins, Olefins and Aromatics in a Mixed Feedstock into Isoparaffins and a Process Thereof - The invention relates to a modified zeolite catalyst, useful for the conversion of paraffins, olefins and aromatics in a mixed feedstock such as FCC gasoline that contain high content of olefin, aromatic and n-paraffin into isoparaffins. The invention further relates to the use of such a catalyst, for example but not limited to, in a process for the conversion of paraffins, olefins and aromatics in a mixed feedstock into the product having high amount of branched paraffins with decreased aromatics and olefins, a useful gasoline blend, with negligible production of lighter gases. | 05-16-2013 |
20130116453 | ORDERED MESOPOROUS TITANOSILICATE AND THE PROCESS FOR THE PREPARATION THEREOF - The invention discloses three-dimensional, ordered, mesoporous titanosilicates wherein the Ti is in a tetrahedral geometry and exclusively substituted for Si in the silica framework. Such titanosilicates find use as catalysts for epoxidation, hydroxylation, C—H bond oxidation, oxidation of sulfides, aminolysis of epoxide and amoximation, with approx. 100% selectivity towards the products. | 05-09-2013 |
20130105397 | MAGNETIC DYE-ADSORBENT CATALYST | 05-02-2013 |
20130096351 | PROCESS FOR THE SELECTIVE HYDROXYLATION OF BENZENE WITH MOLECULAR OXYGEN - The present invention provides an improved process for the selective hydroxylation of benzene. The process provides a direct single step selective vapour phase hydroxylation of benzene to phenol using molecular oxygen (air) over Cu—Cr oxide catalysts. The process provides benzene conversion of 10 to 45% and selectivity for phenol up to 100%. | 04-18-2013 |
20130096333 | Chiral Heterogeneous Catalyst for Assymmetric Nitroaldol Reaction - The present invention relates to the preparation of highly efficient chiral heterogeneous catalyst for asymmetric nitroaldol reaction, wherein Henry reactions of various aldehydes such as aromatic, aliphatic, α,β-unsaturated aldehydes, alicyclic aldehydes and nitroalkenes were carried out to produce optically active β-nitroalcohols in high yield, with moderate to excellent enantioselectivity (ee up to >99%) in presence of a base and an optically active chiral heterogeneous catalyst. | 04-18-2013 |
20130095523 | NOVEL FUNGAL STRAIN BEAUVERIA SP. MTCC 5184 AND A PROCESS FOR THE PREPARATION OF ENZYMES THEREFROM - A fungal strain | 04-18-2013 |
20130087642 | FREE FLOWING 100-500 MICROMETER SIZE SPHERICAL CRYSTALS OF COMMON SALT AND PROCESS FOR PREPARATION THEREOF - The present invention provides spherical shaped crystals of common salt having size distribution in the range of 100-500 μm and a process for preparation of the said salt. The above mentioned size range is relevant for many important edible and non-edible applications of salt. The salt is demonstrated to have superior flow properties compared to the cubic counterpart. The free flow property of the salt can be further enhanced through surface treatment with additive such as glycine. The salt is produced by cost-effective mechanical means and such production is amenable to scale up. | 04-11-2013 |
20130085305 | PROCESS FOR THE PREPARATION OF CU-CR OXIDES FOR SELECTIVE OXIDATION REACTIONS - The present invention provides a process for the preparation of Cu—Cr oxides by hydrothermal synthesis method using hydrazine as a reducing agent and cetyltrimethylammonium bromide as a surfactant and these oxides are very active for selective oxidation of benzene, toluene and ethylbenzene to produce phenol, benzaldehyde and acetophenone, respectively. | 04-04-2013 |
20130079545 | SUBSTITUTED CYCLOHEXANE-1, 3-DIONE COMPOUNDS, PROCESS FOR PREPARATION THEREOF AND ITS APPLICATIONS - A regio-selective and consecutive Michael-Claisen process has been developed for substituted cyclohexane-1,3-dione synthesis started from unsubstituted or substituted acetone and α,β-unsaturated esters. Substituted cyclohexane-1,3-diones are the basic unit found in several natural products, bioactive alkaloids and acridine dione type heterocycles, polyphenols, and unnatural amino acid synthesis. Most of the potent herbicidal and pesticidal active molecules contain cyclohexane-1,3-dione derivatives. Such an important intermediate synthesis using a facile, atom economy and one-pot process is a demandable area in organic synthesis. | 03-28-2013 |
20130074735 | PROCESS FOR THE PRODUCTION OF VIOLACEIN AND ITS DERIVATIVE DEOXYVIOLACEIN CONTAINING BIOACTIVE PIGMENT FROM CHROMOBACTERIUM SP. (MTCC5522) - The present invention discloses a process for producing purple-blue natural pigment containing violacein and its derivative (deoxyviolacein) using | 03-28-2013 |
20130060045 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI MYCOBACTERIAL ACTIVITY - Invention provides antitubercular compounds selected from propargylated 1,2,3 triazoles of Formula I, wherein, X is sulfur (S) or a sulphone (A), n, m represent independently an integer O or 1, with the provision that when ‘n’ is 1, ‘m’ is 1; R1 is hydrogen; C1-C6 linear or branched alkyl group optionally substituted with aryl group; halogen; or aryl group optionally substituted with —OCH3, halogen, and nitro; R2 and R3 are selected from the group consisting of hydrogen, C1-C6 alkyl optionally substituted with heterocyclic ring of 5 to 6 ring atoms containing one to three hetero atoms selected from oxygen, sulfur, nitrogen, which may be substituted with alkyl, arylalkyl, linear or branched alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, or allyl or propargyl groups consisting of 1 to 6 carbon atoms; Z is C1-C6 alkyl optionally substituted with heterocyclic ring of 1 to 6 ring atoms, containing one to three hetero atoms selected from oxygen, sulfur, nitrogen, which may be substituted with arylalkyl, linear or branched alkenyl, substituted alkenyl, alkynyl, substituted alkynyl allyl or propargyl groups consisting of 1 to 6 carbon atoms; with the provision that when ‘m’ is 1, and ‘n’ is zero; R1 is selected from the group consisting of hydrogen, halogen; C1-C6 linear or branched alkyl group optionally substituted with aryl group or aryl group optionally substituted with —OCH3, halogen, and nitro, R2 and R3 are selected from the group consisting of hydrogen, C1-C6 alkyl optionally substituted with heterocyclic ring of 5 to 6 ring atoms containing one to three hetero atoms selected from oxygen, sulfur, nitrogen, which may be substituted with alkyl, arylalkyl, linear or branched alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, or allyl or propargyl groups consisting of 1 to 6 carbon atoms; Z is selected from the group consisting of halogen, C1-C6 linear or branched alkyl group optionally substituted with heterocyclic ring of 1 to 6 ring atoms, containing one to three hetero atoms selected from oxygen, sulfur, nitrogen, wherein the heterocyclic ring may further be substituted with halogen, alkyl, arylalkyl. | 03-07-2013 |
20130059986 | GRAFT COPOLYMER WITH PH DEPENDENT BEHAVIOUR - A graft copolymer with pH dependent behavior of formula 1 Comprises, (i) a backbone having the formula 1 [A | 03-07-2013 |
20130059932 | SURFACE MODIFIED POROUS POLYMERS FOR ENHANCED CELL GROWTH - A process for surface modification of polymer that enhances cell growth as well as inhibits growth of microorganisms is disclosed. | 03-07-2013 |
20130040007 | ANTITUBERCULOSIS COMPOSITION OF BYTTNERIA SPECIES - Active fractions exhibiting anti-tuberculous activity from the plant | 02-14-2013 |
20130034491 | SHAPE PRESERVING CHEMICAL TRANSFORMATION OF ZnO MESOSTRUCTURES INTO ANATASE TiO2 MESOSTRUCTURES FOR OPTOELECTRONIC APPLICATION - The present application discloses a shape preserving chemical transformation of ZnO mesostructures into anatase TiO | 02-07-2013 |
20130030044 | NEW SERIES OF ARTEMISININ DERIVATIVES AND PROCESS FOR PREPARATION THEREOF - This invention relates to the synthesis of certain novel Baylis-Hillman adducts of artremisinin derived aldehyde 2[10′β-deoxoartemisininyl]-ethanal. The capabilities of introduction of three functional groups into a molecule in one step using Baylis-Hillman reaction encouraged us to synthesize some highly functionalized derivatives of artemisinin. These highly functionalized artemisinin derivatives embodied in this document are found to be active against various cancer cell-lines | 01-31-2013 |
20120330031 | Process for the Preparation of Beta-Amino Alcohol - A high-yielding enantioselective synthesis of the bioactive (S)—N-(5-chlorothiophene-2-sulfonyl)- β,β-diethylalaniol (7.b.2), a Notch-1-sparing γ-secretase inhibitor metabolite (with EC | 12-27-2012 |
20120318173 | COMPOSITION FOR BUILDING MATERIAL AND A PROCESS FOR THE PREPARATION THEREOF - The present invention provides a composition and a process for the preparation of chemical activated cold setting fly ash building construction materials. The chemical activator is an alkaline aqueous solution of 11.2 to 13.6 in pH and 1.25 to 1.40 gm/cc in density which contains admixtures of different concentrations of hydroxyl, sulfate, acetate and chloride bearing chemical salts of calcium, magnesium, sodium, potassium and aluminum in water medium. The reaction of chemical activator solution and the mineral constituents of fly ash mix develop binding property. The binding matrix of chemical activated fly ash mix is mostly hydrous silica and silicate group of phases which on setting under atmospheric condition attains strength suitable for building construction application. Utilization of fly ash of any source by weight ranges from 80 to 99% in manufacture of building materials including heat and acid resistance and toxic waste disposal products. | 12-20-2012 |
20120283263 | TRIAZINE-ARYL-BIS-INDOLES AND PROCESS FOR PREPARATION THEREOF - A novel heterocyclic compound belonging to ‘triazine-aryl-bis-indoles’, useful for the treatment of asthma. The pathway by which this compound inhibits asthma is also demonstrated. The present invention also provides a process for the preparation of above compounds and their derivatives are presented. | 11-08-2012 |
20120278945 | NOVEL AUTOTETRAPLOID CLONE 'CIMAP-KHUS 40' OF VETIVER (VETIVERIA ZIZANIODES) USEFUL FOR CARBON SEQUESTRATION AND SOIL CONSERVATION - The present invention relates to the development of a novel clone of Vetiver [ | 11-01-2012 |
20120264597 | CEAlO3 PEROVSKITES CONTAINING TRANSITION METAL - Disclosed herein is a perovskite represented by the following Formula (I): A | 10-18-2012 |
20120245357 | ALR2 INHIBITORS AND THEIR SYNTHESIS FROM A NATURAL SOURCE - A Michael adduct of piplartine, to provide inhibition of ALR2 in vitro (supported by molecular docking) and their potential to suppress the accumulation of sorbitol in erythrocytes when incubated under high glucose conditions; a treatment method using a Michael adduct; and a process for preparing a Michael adduct are provided. | 09-27-2012 |
20120225127 | CLAY NANOCOMPOSITE FORMING MICROCAPSULE USEFUL FOR GUEST ENCAPSULATION AND PROCESS THEREOF - A nanocomposite exhibiting solvent-assisted self-assemblage properties and forming microcapsule useful for guest-encapsulation and process for making the same which comprises the reaction product of a smectite-type clay and an oligosilsesquioxane from hydrolytic polycondensation of a trialkoxy aminoalkyl silane and a trialkoxy alkenyl silane dispensed in a vinyl polymer by in situ intercalative polymerisation of a vinyl monomer. A process for making microcapsule which comprises casting a solution of the nanocomposite in a suitable volatile solvent followed by evaporation of the solvent. A method for producing guest-encapsulated microcapsule which comprises casting a solution of the nanocomposite and the guest molecule in a suitable volatile solvent followed by evaporation of the solvent. | 09-06-2012 |
20120215017 | PROCESS FOR PRODUCING FATTY ACIDS - An effective process for producing fatty acids catalyzed by double metal cyanide complex or a supported group VIb transition metal oxide, wherein the catalyst is stable and reusable. | 08-23-2012 |
20120215011 | Aziridination of Olefins - A process for aziridination of olefins using NaIO4/alkali metal bromide/H | 08-23-2012 |
20120202868 | METHOD FOR TREATMENT OF BRONCHIAL ASTHMA - The present invention relates to a method for the treatment of bronchial asthma and chronic obstructive pulmonary disease (COPD) comprising administering to the patient suffering from asthama and COPD an effective dose of carbazole derivatives or salt thereof, optionally along with pharmaceutically acceptable excipients.
| 08-09-2012 |
20120190071 | LIPA AND ITS VARIANT USEFUL FOR BIOFUEL PRODUCTION - The present invention relates to LipA and its variant that binds to the glucosyl- and acyl chain- region of its glycoside substrate in plant cell walls useful for biofuel production, wherein presence of a hydrophobic pocket confers extensive hydrophobic interaction of the acyl chain with the rest of the tunnel residues. | 07-26-2012 |
20120178614 | Ruthenium Complex Intercalated N-Doped or N,S-Codoped Titania Pillared Montmorillonite and A Process for the Preparation Thereof - This present invention relates to a Ruthenium complex intercalated N-doped or N,S-codoped titania pillared montmorillonite, a multifunctional photocatalyst and a process for the preparation thereof. More particularly, the present invention provides a green photochemical route towards a variety of light driven redox reactions such as organic dye degradations, photocatalytic water splitting and various organic transformation reactions oriented to the synthesis of fine chemicals. | 07-12-2012 |
20120141915 | Process for the Preparation of Sol-Gel Modified Alternative Nafion-Silica Composite Membrane Useful for Polymer Electrolyte Fuel Cell - The present invention provides a process for the preparation of sol-gel modified alternative Nafion-Silica composite membrane useful for polymer electrolyte fuel cell. The said composite membrane is made by embedding silica particles in perfluorosulfonic acid ionomer by a process that circumvents the use of added acid while using acidic characteristics of Nafion and polymerization reaction through a sol-gel route. The composite membrane has high affinity for water with capability to exchange protons. The approach may be used to manufacture polymer electrolyte membrane fuel cells operating at elevated temperatures under near-zero humidity. | 06-07-2012 |
20120130047 | ACCELERATED GELATION OF REGENERATED FIBROIN - The invention discloses a process for the acceleration of gelling time of regenerated silk fibroin using gelling agent, preferably silica to create a porous structure, devoid of microbial growth. | 05-24-2012 |
20120129223 | DNA LOADED SUPPORTED GOLD NANOPARTICLES, PROCESS FOR THE PREPARATION AND USE THEREOF - The present invention relates to DNA loaded gold nanoparticles embedded in sharp carbonaceous carriers useful for higher DNA delivery efficiently into plants. These nanogold embedded carbon matrices are prepared by heat treatment of biogenic intracellular gold nanoparticles. The DNA delivery efficiency is tested on model plants. These materials reveal good dispersion of the transport material, producing a greater number of GUS foci per unit area. The added advantages of the composite carrier are the lower plasmid and gold requirements. Plant cell damage with the prepared carbon supported particles is very minimal and can be gauged from the increased plant regeneration and transformation efficiency compared to that of the commercial micrometer sized gold particles. This can be attributed to the sharp edges that the carbon supports possess, which lead to better piercing capabilities with minimum damage. | 05-24-2012 |
20120125844 | REMOVAL OF ORGANIC DYES AND ORGANIC POLLUTANTS BY TITANIUM PEROXIDE GEL - The one step process of removal of chromophore/dye/organic pollutant from a solution comprising a polymer free titanium oxide gel i.e. high zeta potential is disclosed. The concentration of the chromophores is removed up to 95-100%. | 05-24-2012 |
20120101270 | NOVEL PYRROLO[2,1-C][1,4] BENZODIAZEPINE DERIVATIVES WITH DITHIOCARBAMATE SIDE CHAINS AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides synthesis and in vitro anticancer activity of novel pyrrolo[2,1-c][1,4]benzodiazepine derivatives with dithiocarbamate side chains. The present invention also relates to a process for the preparation of new pyrrolo[2,1-c][1,4]benzodiazepine derivatives with dithiocarbamate side chains of general formula (A) and a process for the preparation thereof. | 04-26-2012 |
20120098169 | PROCESS FOR MANUFACTURING HIGH DENSITY SLIP-CAST FUSED SILICA BODIES - Fused silica ceramics plays demanding role in high velocity missile/aircraft'radome development. Slip casting is the most common and commercially viable process utilized for radome production. Unfortunately slip casting cannot afford high density due to its poor green packing density which in turn results in poor rain erosion resistance. Present invention discloses process for preparing high density fused silica bodies by adding boron oxide (B | 04-26-2012 |
20120095214 | QUINAZOLINONE LINKED PYRROLO[2,1-C][1,4]BENZODIAZEPINE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides a compound of general formulae 5a-r, 9a-i to 13a-i and 17a-i to 22a-i, useful as potential antitumour agents against human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]benzodiazepine hybrids of general formulae 5a-r, 9a-i to 13a-i and 17a-i to 22a-i. | 04-19-2012 |
20120070835 | Method of Cloning Stable Stress Tolerant Superoxide Dismutase Using Universal Primers - The present invention relates to a method of cloning stable stress tolerant superoxide dismutase from diverse plant species using universal primers. | 03-22-2012 |
20120059131 | PH SENSITIVE GRAFT COPOLYMER - Graft copolymer (P) which exhibit pH dependent swelling/dissolution properties comprising a hydrophobic back-bone and graft chains comprising acidic monomer. This Graft copolymer (P) do not swell or dissolve at acidic pH prevalent in the stomach and they swell/dissolve at near neutral pH prevalent in the intestinal region. The graft copolymer (P) is useful for the development of drug delivery formulations particularly for oral drug delivery formulations. | 03-08-2012 |
20120009132 | Transparent Xyloglucan/Chitosan Gel and a Process for the Preparation Thereof - The present invention provides a transparent Xyloglucan/Chitosan gel and a process to prepare the same which comprises of extracting the xyloglucan from tamarind seed powder by a suitable solvent at a high temperature and precipitating the xyloglucan by alcohol and then modifying the xyloglucan to form dialdehyde and making a co-polymer with chitosan to form a thermo stable crystal clear, colourless gel which is stable at temperature −20 to 90. A transparent chitam gel and a process for the preparation thereof C and pH 3-7, having an average molecular weight of 4730 KDa and a viscosity of 4100 centi Poises at 28±2° C., not digested by digestive enzymes in humans and does not contribute to calorie intake can be used as a food ingredient, and supplement functional foods (nutritional care). This Xyloglucan/Chitosan gel has applications in the area of cosmetic and personal care products, as an ultraviolet protective agent or as a tissue adhesive which can be used, including haemostasis, wound sealing, tissue engineering or localised drug delivery as capsules & tablets. | 01-12-2012 |
20120001412 | Surface Modified Optically Variable Product for Security Feature - Surface modified optically variable product to provide security features in packaging materials and currency notes to prevent counterfeiting. Surface modified optically variable product is optionally readily functionalized to disperse them in organic and aqueous inks. | 01-05-2012 |
20110319777 | ECG DEVICE WITH IMPULSE AND CHANNEL SWITCHING ADC NOISE FILTER AND ERROR CORRECTOR FOR DERIVED LEADS - The present invention provides a device and method for filtering impulsive noise and channel switching noise at ADC in an ECG device with multiplexed ESCs. The filtering is based on an implementation of Burst Sampling technique also a method for correcting errors in derived leads caused by time delays due to sequential sampling of different ECG signals is also provided. Real time digital FIR filters are used for removing other types of noise in ECG signals. The ECG device is compact and light weight and includes features of self calibration, clip detection and drawing of power from USB port of a PC, batteries or an external power source. The ECG monitoring device of the present invention measures real time ECG signals with automated data recording, data storage and retrieval, data transmission/transfer to an external system, along with parameter extraction for ECG analysis in an efficient manner for quick and reliable ECG measurement, in an extremely cost effective manner. | 12-29-2011 |
20110289631 | METHOD FOR PRODUCING MALE STERILE PLANTS - The present invention relates to a method for producing male sterile plants. It involves selective killing of reproductive cells in plants by using an autophagy related gene plant BECLIN I/ATG6. An expression cassette comprising plant BECLIN I/ATG6, regulated by a tapetum specific promoter can induce killing of tapetum cells. A particular area of interest is transforming a plant with said genetic construct and expression of the plant BECLIN I/ATG6 gene in tapetum at early stage of anther development to cause early collapse of tapetum to produce nonviable pollen, thus imparting male sterility in plants. | 11-24-2011 |
20110282084 | CASTOR OIL FATTY ACID BASED ESTOLIDE ESTERS AND THEIR DERIVATIVES AS POTENTIAL LUBRICANT BASE STOCKS - Castor oil was hydrolysed to castor fatty acids and self condensed to get a ricinoleic acid-based estolide of about acid value. The carboxylic group of the estolide on subsequent esterification with linear or branched chain alcohols and also on acetylation of free hydroxy group yielded castor oil fatty acids based estolide esters and their acetates. All the products were evaluated for total acid number (TAN), viscosity, viscosity index, pour point, flash point, and copper strip corrosion and found to be potential lubricant basestocks. | 11-17-2011 |
20110269987 | Process for Preparation of Hexadecyl Cis-9-Tetradecenoate and Hexadecyl Cis-10-Tetradecenoate - Hexadecyl cis-9-tetradecenoate commonly known as Cetyl myristoleate (CMO) is being used for the treatment of osteoarthritis and other joint inflammatory diseases, cis-9-Tetradecenoic acid (cis-9-myristoleic acid) is the main precursor for the preparation of CMO. As there are limited natural plant sources for cis-9-tetradecenoic acid, the present invention aimed at the synthesis of cis-9-tetradecenoic acid methyl ester from oleic acid methyl ester. As oleic acid is not available in pure form, this has to be isolated from oleic acid-rich oils like olive oil. cis-10-Tetradecenoic acid methyl ester, an isomer of cis-9-tetradecenoic acid was also prepared from undecenoic acid methyl ester, a derivative of castor oil. Undecenoic acid is easily available commercially in pure form. Hexadecyl cis-9-tetradecenoate and hexadecyl c/s-10-tetradecenoate were prepared by enzymatic transesterification of cis-9-tetradecenoic acid methyl ester and cis-10-tetradecenoic acid methyl ester with 1-hexadecanol (cetyl alcohol) respectively. Both the isomers of cetyl myristoleate were evaluated for anti arthritis, blocking inflammation and reduction of adjuvant-induced arthritis in rats. | 11-03-2011 |
20110257439 | Process for the Preparation of 4-(4-hydroxyphenyl)butan-2-one Using Solid Acid Clay Catalyst - Solid acid catalyst such as acid activated-Montmorillonite clay composite has been developed by modifying the Na-Montmorillonite clay with acid (HCl) treatment for different periods such as 5 minutes to about 4 hours and activating at about 12O° C. for about 2 hours. Friedel Crafts alkylation reaction between phenol and 4-hydroxybutan-2-one in presence of the acid activated Montmorillonite clay catalysts exhibiting layered clay structures (basal spacing d | 10-20-2011 |
20110244003 | Self Standing Nanoparticle Networks/Scaffolds with Controllable Void Dimensions - The present invention discloses a self standing network or scaffold of nanoparticles with controllably variable mesh size between 500 nm and 1 mm having particle volume fraction between 0.5 to 50%. The network comprises nanoparticles, a surfactant capable of forming ordered structured phases and a cross linking agent, wherein the surfactant is washed off leaving the self standing scaffold. The invention further discloses the process for preparing the self standing scaffolds and uses thereof. | 10-06-2011 |
20110237471 | PROCESS FOR METALWORKING FLUID FROM HEAVY ALKYLATE - The present invention relates to composition of metalworking fluid based on heavy alkyl benzenes having 20 to 22 alkyl carbon atoms and process for the preparation thereof. The heavy alkyl benzene based, less toxic, soluble metalworking fluid composition comprises heavy alkyl benzene, emulsifier, lubricity booster, antioxidant, fungicide, extreme pressure additive, antirust, co-surfactant, coupling agent and alkali component. The process comprises tailoring the heavy alkyl benzene, removing of insoluble matter from the heavy alkylate, addition of emulsifier, additives, coupling agent and co-surfactant, homogenizing the mixture at 20-120° C., followed by conditioning of the soluble metal working fluid concentrate which can be used as emulsion in water. | 09-29-2011 |
20110213165 | NOVEL 4BETA-AMINO PODOPHYLLOTOXIN CONGENERS AS ANTI TUMOUR ANTIBIOTICS A PROCESS FOR THE PREPARATION THEREOF - The present invention provides novel β-amino podophyllotoxin congeners of general formula (A); R═CH | 09-01-2011 |
20110207924 | NEW PHENANTHRYLPHENOL LINKED PYRROLO [2, L-C] [L, 4] BENZODIAZEPINE HYBRIDS AS POTENTIAL ANTITUMOUR AGENTS AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides a compounds of general formula (6), useful as potential antitumour agents against human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]benzodiazepine hybrids of general formula (6). | 08-25-2011 |
20110201661 | Spiro Derivatives of Parthenin as Novel Anticancer Agents - The present invention relates to novel spiro derivatives of parthenin prepared by the dipolar cycloaddition of various dipoles viz, benzonitrile oxides, nitrones, azides, nitrile ylide diazoalkane, nitrile imide, ozone, azomethine imides, azomethine ylides etc. with exocyclic double bond of C ring (α-methylene-γ-butyrolactone). Representative compounds have been screened for their anticancer activity against different cancer cell lines. ICs0 value of these analogues varies between 4.3 μM to 93 μM. A mechanistic correlation of their anticancer activity has been described. The results of the cytotoxicity test of the compounds studies indicated that the α,β-unsaturated ketonic moiety in parthenin plays an important role in the maintenance of the high level of cytotoxicity. | 08-18-2011 |
20110201495 | PROCESS FOR THE PREPARATION OF 1,1,1,2-TETRAFLUOROETHANE - The present invention relates to a process for preparing a co-precipated Cr | 08-18-2011 |
20110196141 | LOCKED AND UNLOCKED 2'-O PHOSPHORAMIDITE NUCLEOSIDES, PROCESS OF PREPARATION THEREOF AND OLIGOMERS COMPRISING THE NUCLEOSIDES - The present invention relates to 2′-O-phosphoramidite of locked nucleoside and unlocked nucleoside, their synthesis and 2′-5′-linked oligomers oligomers comprising the nucleosides to delineate the structural requirements of 2′-5′ RNA/DNA: 3′-5′ RNA duplexes and also for use in antisense applications. | 08-11-2011 |
20110183968 | ANTIFUNGAL COMPOUNDS CONTAINING BENZOTHIAZINONE, BENZOXAZINONE OR BENZOXAZOLINONE AND PROCESS THEREOF - The present invention discloses novel compounds of the Formula (1), comprising benzothiazinone, benzoxazinone or benzoxazolinone moieties having antifungal activity, method for preparing these compounds and the use of these compounds as antifungal agents in prevention and treatment of fungal infections, and pharmaceutical preparations containing these novel compounds. | 07-28-2011 |
20110171561 | COMPOSITION WITH ENHANCED PROTON CONDUCTIVITY - A composition showing enhanced proton conductivity comprising at least a polymer with an ionizable group (A) containing a proton and carbon nanostructures functionalized with ionizable group (B) containing a proton is disclosed where A and B are same or different. | 07-14-2011 |
20110142969 | EXTRACT OF PIPER BETEL LEAVES FOR THE TREATMENT OF HUMAN MALIGNANCIES BY INDUCING OXIDATIVE STRESS - This invention relates to method of treating human malignancies of different origin that are sensitive to oxidative stress by administering effective amount of extract of | 06-16-2011 |
20110131667 | Tumor Model System Useful to Study Multistage Cancer - The present invention relates to a method of developing a Tumor Model System. The invention deals with a tumor model system with adhesion deprived cells. This observation provides a new method for primary detection of transformation of adhesion-deprived cells and tumorigenicity. The adhesion-deprived cells are capable of metastasizing at distant sites and the model system includes both the tumor formation and metastasis. | 06-02-2011 |
20110124896 | A 9,10,12-TRIACYLOXY OCTADECANOIC ACID ALKYL ESTER AND 9,10,12-TRIACYLOXY OCTADECANOIC ACID ALKYL ESTER RICH FATTY ACID ALKYL ESTERS MIXTURE AND A PROCESS FOR PREPARATION THEREOF - The present invention relates to modification of the chemical structure of ricinoleic acid, which is present to an extent of 85-90% in castor oil into triacyloxy alkyl ester derivatives. Accordingly, 9,10,12-trihydroxy octadecanoic acid rich fatty acid mixture was prepared from castor oil and converted to their alkyl esters followed by acylation of hydroxy groups to get 9,10,12-triacyloxy octadecanoic acid alkyl ester rich fatty acid alkyl esters mixture. The 9,10,12-triacyloxy octadecanoic acid alkyl esters were purified from the crude product and characterized by | 05-26-2011 |
20110118237 | Isoxazoline linked pyrrolo[2,1-c][1,4]benzodiazepine hybrids as potential anticancer agents and the process for preparation thereof - The present invention provides compounds of general formula (5a-d) and (9a-h) useful as potential antitumour agents against human cancer cell lines. The present invention also provides a process for the preparation of pyrrolo [2,1-c][1,4]benzodiazepine hybrids of general formula (5a-d) and (9a-h). | 05-19-2011 |
20110117522 | DENTAL IMPLANT SYSTEM - The invention provides a screw type dental implant system ( | 05-19-2011 |
20110107461 | CLONING OF NOVEL GENE SEQUENCES EXPRESSED AND REPRESSED DURING WINTER DORMANCY IN THE APICAL BUDS OF TEA - The present invention relates to cloning of novel gene sequences expressed and repressed during winter dormancy in the apical buds of | 05-05-2011 |
20110092740 | SINGLE-STEP CATALYTIC PREPARATION OF PARA-AMINOPHENOL - The method of using a bi-functional catalyst for the one-step preparation of para-aminophenol. The catalyst includes a mixture of a hydrogenation noble metal and a zirconium sulfate. Also, an improved single-step process for the preparation of para-aminophenol from nitrobenzene, in an aqueous medium, using the bi-functional catalyst. | 04-21-2011 |
20110028440 | Simultaneous Method for the Preparation of a Mixture of 3-acetoxy-17-acetamido-16-formyl-androst-5,17-diene and 3-acetoxy-2'-chloro-5-androsteno[17,16-b]pyridine - The present invention relates to preparation and biological evaluation of 3-acetoxy-17-acetamido-16-formyl-androst-5,17-diene (4) and 3-acetoxy2′-chloro-5-androsteno[17,16-b]pyridine (5) as gastric proton pump inhibitor and their comparison to that of omeprazole, a clinically employed anti-gastric ulcer drug. Compound (4) exhibited dose dependent inhibition of histamine-stimulated acid secretion in gastric parietal cell with an IC | 02-03-2011 |
20110027784 | Novel Primers for Identification of Astrocytoma, Its Grades and Glioblastoma Prognosis - The present invention relates to novel primers for identification of astrocytoma, it's grades and glioblastoma prognosis. Further, disclosed is a method of diagnosing the presence of different grades of diffuse astrocytoma and glioblastoma, in a human subject, which involves detection of the expression levels of said genes in tumor tissue samples in comparison to normal brain. Also disclosed is a method of distinguishing between the two types of Glioblastoma—the progressive and de novo types. Also disclosed is a method of prognosis of glioblastoma based on the expression of the gene PBEF1, wherein the higher level of expression of the gene in the tumor sample, indicates poorer survival of the human subject. The disclosed compositions are useful, for example, in the diagnosis, prevention, treatment and/or prognosis of astrocytoma. The invention further provides kits for the detection and prognosis of the said diseases. | 02-03-2011 |
20100330277 | NANOCOMPOSITE MATERIAL USEFUL FOR THE PREPARATION SUPERHYDROPHOBIC COATING AND A PROCESS FOR THE PREPARATION THEREOF - The present invention provides nanocomposite materials comprising carbon nanotubes and oligo(p-phenylenevinylene) (OPV). Dispersion of CNT in the solution of solution of oligo(p-phenylenevinylene) (OPV) in organic solvent results in the formation of nanocomposite material. The π-π interaction between CNT and OPV molecule were shown by spectroscopic and microscopic techniques. The nanocomposite solution can be drop casted over glass or metallic surface for the preparation of superhydrophobic coating. The resultant composite surface shows superhydrophobic nature even with corrosive liquids and its contact angle is almost constant even after prolonged contact with water. | 12-30-2010 |
20100304272 | PROTON CONDUCTING POLYMER ELECTROLYTE MEMBRANE USEFUL IN POLYMER ELECTROLYTE FUEL CELLS - The present invention provides an alternate proton conducting polymer electrolyte membrane and a process for the preparation thereof. More particularly the present invention provides a conducting hybrid polymer electrolyte membrane comprising a stable host polymer and a proton-conducting medium as a guest polymer for its suitability in PEM-based fuel cells. The present invention deals with host polymer, comprising a group of poly (vinyl alcohol), poly (vinyl fluoride), polyethylene oxide, polyethyleneimine, polyethylene glycol, cellulose acetate, polyvinylmethylethyl ether, more preferably polyvinyl alcohol and a guest polymer comprising poly(styrene sulfonic acid), poly(acrylic acid), sulfonated phenolic, polyacrylonitrile, polymethyl acrylate, and quaternary ammonium salt, more preferably poly(styrene sulfonic acid). | 12-02-2010 |
20100286425 | ORGANIC-INORGANIC HYBRID CHIRAL SORBENT AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides an organic-inorganic hybrid chiral sorbent for chiral resolution of various racemic compounds viz. racemic mandelic acid, 2-phenyl propionic acid, diethyl tartrate, 2,2′-dihydroxy-1,1′-binaphthalene (BINOL) and cyano chromene oxide with excellent chiral separation (enantiomeric excess, 99%) in case of mandelic acid under medium pressure column chromatography. These optically pure enantiomers find applications as intermediates in pharmaceutical industries. | 11-11-2010 |
20100284858 | PYRROLE END-CAPPED BIPYRIDINE ASSAY POWDER FOR SELECTIVE DETECTION OF ZINC IONS AND A PROCESS FOR THE PREPARATION THEREOF - The present invention provides pyrrole end-capped bipyridine derivative having a general formula (1) useful for the detection of zinc ions in solution. The present invention also provides a process for the preparation of pyrrole end-capped bipyridine derivative having a general formula (1). The present invention further provides a dipstick device by coating the assay powder of formula (1) in alumina over a thermoplastic or a glass solid support. The detection event can be monitored by noting the color change and the intense fluorescence change on the surface of the dipstick. For zinc ions, in addition to the color change an intense fluorescence change from greenish-yellow to red is observed. Detection event by means of fluorescence change is selective for Zn | 11-11-2010 |
20100249451 | PROCESS FOR THE PREPARATION OF SUBSTITUTED BENZILIC ACID FROM SUBSTITUTED BENZILS - The classical process for the rearrangement of substituted benzil to benzilic acid is performed in the presence of sodium or potassium hydroxide as a base using ethanol-ether as a medium. The reaction requires reflux temperature for complete conversion. However, these bases containing metallic ions and generate metallic containing effluent waste which may require additional expenditure for treatment. Moreover, because of corrosive nature of base, and use of flammable solvent, the safety measures are needed during large scale production. Another method also reported for benzilic acid rearrangement at 380° C. which is practically not feasible. The present invention describes the use of quaternary ammonium hydroxides as a base for the rearrangement of the substituted benzils to benzilc acids. It also avoids the use of solvent and reaction can be carried out at relatively lower temperatures. Because of the solvent free reaction condition it reduces the mass/volume of reaction mixture. | 09-30-2010 |
20100205853 | Process for the Preparation of Biodiesel from Vegetable Oils Containing High FFA - The present invention provides an improved process for the preparation of biodiesel from crude vegetable oils especially Jatropha ( | 08-19-2010 |
20100147683 | NOVEL POTENTIOMETRIC CHOLESTEROL SENSOR FOR THE QUANTITATIVE ESTIMATION OF TOTAL CHOLESTEROL IN HUMAN BLOOD SERUM - The present invention provides a novel sensor for the estimation of total cholesterol in human blood serum using molecular imprint of cholesterol. Human blood serum contains 150-250 mg/dl cholesterol. The present invention provides a sensor device and a process for the fabrication of ISFET (Ion Selective Field Effect Transister) coated with molecular imprint of cholesterol on the SiO | 06-17-2010 |
20100136635 | Method of Inducing Chirality to Epoxides Using 2,3:4,6 di-O-isopropylidene-2-keto-L-gulonic Acid Monohydrate - The present invention relates to a recyclable method to prepare chirally pure epoxides directly from olefins using a novel chiral acid 2,3:4,6-di-O-isopropylidene-2-keto-L-gulonic acid monohydrate as chiral inducer and anhydrous hydrogen peroxide in the form of urea hydrogen peroxide adduct (UHP) as oxidant and lipase enzyme as catalyst. Under the influence of lipase, the chiral acid 2,3:4,6-di-O-isopropylidene-2-keto-L-gulonic acid monohydrate is converted to per-acid in situ by the oxidant urea hydrogen peroxide which in turn transfers oxygen to olefin inducing chirality to the product epoxide. Using this technique, important epoxide building blocks of different industrially important compounds can be prepared with good yield and moderate enantioselectivity. Chiral epoxidation of olefins with environment friendly catalytic system that can be recycled is highly desirable in the context of Green Chemistry for preparation of many industrially important compounds. | 06-03-2010 |
20100089142 | PROCESS UTILIZING NATURAL CARBON-13 ISOTOPE FOR IDENTIFICATION OF EARLY BREAKTHROUGH OF INJECTION WATER IN OIL WELLS - This invention relates to a process utilizing natural carbon-13 isotope for identification of early breakthrough of injection water in oil wells. All natural water sources are labeled by unique ratios of carbon isotopes ( | 04-15-2010 |
20090306213 | Process for Synthesis of Glycomimicking Cationic Amphiphiles - The present invention provides processes for the synthesis of novel Shikimic acid head-group containing non-toxic cationic amphiphiles capable of facilitating transport of biological macromolecules into cells. | 12-10-2009 |
20090302263 | CONDUCTING COPOLYMER FERROMAGNETIC COMPOSITE AND A PROCESS FOR THE PREPARATION THEREOF - The present invention provides a conducting copolymer ferromagnetic composite. Particularly, the present invention relates to a conducting copolymer of aniline and ethylene-dioxy thiophene containing ferrite particles. The present invention also provides insitu polymerization of aniline and ethylene-dioxy thiophene in the presence of ferrite particles and suitable surfactant medium. This conducting copolymer ferromagnetic composite can be used for the dissipation of electrostatic charge, for the shielding of electromagnetic interference and as absorbing of electromagnetic waves in the microwave region. | 12-10-2009 |
20090298938 | USE OF SEMI SYNTHETIC ANALOGUES OF BOSWELLIC ACIDS FOR ANTICANCER ACTIVITY - The present invention relates to use of compounds of general formula 1 for anticancerous activity, wherein the said compound being derived semi-synthetically from natural triterpenoic acids known as boswellic acids by the induction of apoptosis thereof cytotoxicity and anti-cancer activity displayed by semi-synthetic analogues of natural triterpenes, known as Boswellic acids. These compounds may be used for the treatment of cancer, alone or in combination with pharmaceutically acceptable or other carriers, displaying cytotoxicity and anti-cancer activity for colon, prostrate, liver, breast, central nervous system (CNS), leukemia and malignancy of other tissues, including ascites and solid tumors. The cancer cell death is mediated by induction of apoptosis and inhibition of cell proliferation at specific doses. | 12-03-2009 |
20090292154 | Modified Zeolite Catalyst Useful for the Conversion of Paraffins, Olefins and Aromatics in a Mixed Feedstock into Isoparaffins and a Process Thereof - The invention relates to a modified zeolite catalyst, useful for the conversion of paraffins, olefins and aromatics in a mixed feedstock such as FCC gasoline that contain high content of olefin, aromatic and n-paraffin into isoparaffins. The invention further relates to the use of such a catalyst, for example but not limited to, in a process for the conversion of paraffins, olefins and aromatics in a mixed feedstock into the product having high amount of branched paraffins with decreased aromatics and olefins, a useful gasoline blend, with negligible production of lighter gases. | 11-26-2009 |
20090250660 | COMPOSITION FOR BUILDING MATERIAL AND A PROCESS FOR THE PREPARATION THEREOF - The present invention provides a composition and a process for the preparation of chemical activated cold setting fly ash building construction materials. The chemical activator is an alkaline aqueous solution of 11.2 to 13.6 in pH and 1.25 to 1.40 gm/cc in density which contains admixtures of different concentrations of hydroxyl, sulfate, acetate and chloride bearing chemical salts of calcium, magnesium, sodium, potassium and aluminum in water medium. The reaction of chemical activator solution and the mineral constituents of fly ash mix develop binding property. The binding matrix of chemical activated fly ash mix is mostly hydrous silica and silicate group of phases which on setting under atmospheric condition attains strength suitable for building construction application. Utilization of fly ash of any source by weight ranges from 80 to 99% in manufacture of building materials including heat and acid resistance and toxic waste disposal products. | 10-08-2009 |
20090247626 | Method of Treating Dyslipidemia Using Naturally Occurring Diterpene - A method for treatment and or/prevention of dyslipidemia is provided. The invention relates to reducing low density lipoprotein cholesterol concentration by using naturally occurring diterpene (16α-hydroxycleroda-3,13(14)Z-dien-15,16-olide, a compound having formula (1)) isolated from leaves of | 10-01-2009 |
20090246302 | COMPOSITION AND METHOD FOR PROTECTING AGRICULTURAL CROPS AND/OR AGRICULTURAL PRODUCTS - The present invention provides a composition and a method for protecting agricultural crops and/or agricultural products against insects/pests. The said composition comprising an effective amount of extract obtained from | 10-01-2009 |
20090233337 | Chemoenzymatic Process for the Stereoselective Preparation of (R)-Gamma-Amino-Beta-Hydroxybutyric Acid [(R)-GABOB) and (R)-Carnitine - The present invention provides a chemoenzymatic process for the preparation of (R)-GABOB and (R)-carnitine employing lipase-mediated resolution of 3-hydroxy-4-tosyloxybutanenitrile as the key step. The drawing accompanying this specification represents the preparation of racemic 3-hydroxy-4-tosyloxybutanenitrile, its lipase-mediated kinetic resolution and its successful application in the preparation of (R)-GABOB and (R)-carnitine. | 09-17-2009 |
20090209437 | TEMPERATURE REGULATED PROMOTERS FROM SCHIZOSACCHAROMYCES POMBE FOR EXPRESSION OF PROTEINS - The present invention relates to novel temperature promoters and set of expression vectors isolated from | 08-20-2009 |