Canfield Scientific, Incorporated Patent applications |
Patent application number | Title | Published |
20150374277 | ACNE IMAGING METHODS AND APPARATUS - Methods and apparatus are described for detecting acne, particularly in its earliest stages before any humanly visible or palpable manifestations thereof have emerged. An arrangement is described in which a green fluorescence image of an area of skin illuminated with blue light is captured and processed to detect the presence of microcomedones. The captured green fluorescence image is corrected for the non-uniform distribution of excitation light on the surface of the illuminated area of skin. Fluorescent spots are then detected in the corrected image. The subset of fluorescent spots having an intensity lower than an intensity threshold and an area smaller than an area threshold are selected as representative of candidate microcomedones. The subset can be further refined by eliminating fluorescent spots that have irregular shapes, are associated with inflammation, or exhibit comedone features. Additional filtering can be applied by selecting those spots whose locations correspond to those of pores. A dermatoscope with a blue illumination source and a green-filtered viewer allows live imaging of skin spots indicative of acne, including microcomedones not otherwise visible with the naked eye. | 12-31-2015 |
20140364745 | MULTI-SPECTRAL TISSUE IMAGING - Apparatus and methods are disclosed for multi-spectral imaging of tissue to obtain information about the distribution of fluorophores and chromophores in the tissue. Using specific spectral bands for illumination and specific spectral bands for detection, the signal-to-noise ratio and information related to the distribution of specific fluorophores is enhanced as compared to UV photography, which uses a single RGB image. Furthermore, the chromophore distribution information derived from the multi-spectral absorption images can be used to correct the fluorescence measurements. The combined fluorescence, absorption, and broadband reflectance data can be analyzed for disease diagnosis and skin feature detection. | 12-11-2014 |
20140243685 | DERMATOSCOPE DEVICES - A dermatoscope has a generally circular viewing opening, a plurality of light sources including first and second groups of light sources arranged about the viewing opening, a first polarizer for polarizing light passing through the viewing opening, and a second polarizer for polarizing light emitted from the first group of light sources, wherein the first and second groups of light sources are arranged at different distances from a center of the viewing opening so that light from the second group of light sources is not polarized by the second polarizer. A further dermatoscope has a head portion including a generally circular viewing opening, and at least one light source arranged proximate to the viewing opening; and a body portion including an image capture device, wherein the head portion is pivotally attached to the body portion selectively allowing alignment of the center of the viewing opening with the center of the field of view of the image capture device. Yet a further dermatoscope has a generally circular viewing opening, a selectively extendable element that can be selectively extended coaxially with the viewing opening, and a contact element for contacting a surface to be viewed, the contact element being removably attachable to a distal end of the selectively extendable element. | 08-28-2014 |
20130236074 | SYSTEMS, DEVICES, AND METHODS FOR IMAGE ANALYSIS - Embodiments of a system for performing image analysis include a calibration device comprising a first color correction region comprising a predetermined plurality of color chips; and a memory component that stores logic, that when executed, causes a processor to perform at least the following: access a digital image of a subject, the digital image comprising a portion of a skin of the subject, the digital image comprising a portion of the calibration device; calibrate the digital image using the first color correction region; analyze a condition within the digital image; and output one or more results corresponding to the condition within the digital image. | 09-12-2013 |
20130058543 | SYSTEMS, DEVICES, AND METHODS FOR IMAGE ANALYSIS - Embodiments of a method for performing image analysis include accessing a digital image of a subject, the digital image comprising a portion of a target substrate of the subject, the digital image comprising a portion of a calibration device; detecting a position of the calibration device by searching the digital image for a predetermined background color; detecting a plurality of color chips on the calibration device; mapping a position of the plurality of color chips on the digital image, each of the plurality of color chips comprising a predetermined chip color; comparing at least a portion of the plurality of color chips with a predetermined color standard; and altering the digital image, based on the comparison, to provide consistent image parameters with other images of the subject. | 03-07-2013 |
20110206254 | REFLECTANCE IMAGING AND ANALYSIS FOR EVALUATING TISSUE PIGMENTATION - Methods and apparatus are described that provide the ability to estimate the diffuse reflection component of an image of tissue such as skin captured without cross-polarization. It is thereby possible to estimate skin pigmentation information from an image of skin captured conventionally, such as, for example, a total reflection image, obtained in a conventional manner by shining white light on the skin and capturing the reflected light. The image may also be a partially diffuse reflection image, such as a low quality cross-polarized image. The diffuse reflection component of a captured image can then be further processed to obtain Red and Brown pigmentation images, useful for indicating the distribution of hemoglobin and melanin, the primary chromophores of skin. Additionally, a standard captured image of skin can be analyzed to obtain an estimate of the surface reflection component of the reflected light. The surface reflection component can then be used to generate a surface reflection image, useful for showing the distribution of light on the skin and to highlight superficial features such as wrinkles, fine lines, folds, pores, texture, and visible spots. | 08-25-2011 |
20090196475 | AUTOMATIC MASK DESIGN AND REGISTRATION AND FEATURE DETECTION FOR COMPUTER-AIDED SKIN ANALYSIS - Methods and systems for automatically generating a mask delineating a region of interest (ROI) within an image containing skin are disclosed. The image may be of an anatomical area containing skin, such as the face, neck, chest, shoulders, arms or hands, among others, or may be of portions of such areas, such as the cheek, forehead, or nose, among others. The mask that is generated is based on the locations of anatomical features or landmarks in the image, such as the eyes, nose, eyebrows and lips, which can vary from subject to subject and image to image. As such, masks can be adapted to individual subjects and to different images of the same subjects, while delineating anatomically standardized ROIs, thereby facilitating standardized, reproducible skin analysis over multiple subjects and/or over multiple images of each subject. Moreover, the masks can be limited to skin regions that include uniformly illuminated portions of skin while excluding skin regions in shadow or hot-spot areas that would otherwise provide erroneous feature analysis results. Methods and systems are also disclosed for automatically registering a skin mask delineating a skin ROI in a first image captured in one imaging modality (e.g., standard white light, UV light, polarized light, multi-spectral absorption or fluorescence imaging, etc.) onto a second image of the ROI captured in the same or another imaging modality. Such registration can be done using linear as well as non-linear spatial transformation techniques. | 08-06-2009 |