ADVANCED NEUROMODULATION SYSTEMS, INC. Patent applications |
Patent application number | Title | Published |
20150157851 | MEDICAL LEADS WITH SEGMENTED ELECTRODES AND METHODS OF FABRICATION THEREOF - In one embodiment, a method for fabricating a neurostimulation stimulation lead comprises: providing a plurality of ring components and hypotubes in a mold; placing an annular frame with multiple lumens over distal ends of the plurality of hypotubes to position a portion of each hypotube within a respective lumen of the annular frame; molding the plurality of ring components and the hypotubes to form a stimulation tip component for the stimulation lead, wherein the molding fills interstitial spaces between the plurality of ring components and hypotubes with insulative material; and forming segmented electrodes from the ring components after performing the molding. | 06-11-2015 |
20140350650 | LEADS FOR NEUROSTIMULATION AND METHOD OF ASSEMBLING THE SAME - A neurostimulator lead including an elongated lead body having stimulating and proximal end portions and a center axis extending therebetween. The lead body includes an inner tubing that extends along the center axis. The inner tubing includes wire conductors that extend between the stimulating and proximal end portions. The lead also includes multiple electrode-inductor assemblies that are positioned along the stimulating end portion and spaced apart from one another along the center axis. Each of the electrode-inductor assemblies includes an inductor coil that is electrically coupled to one of the wire conductors and an electrode that is located proximate to the inductor coil. The electrode and the inductor coil are electrically joined, and the inductor coil is configured to prevent a flow of induced current that occurs when the lead is exposed to external magnetic fields. | 11-27-2014 |
20140200639 | SELF-EXPANDING NEUROSTIMULATION LEADS HAVING BROAD MULTI-ELECTRODE ARRAYS - Self-expanding lead including a lead body having a distal body end, a proximal body end, and a central axis extending therebetween. The lead body includes first and second outer arms and an inner arm disposed between the first and second outer arms. The first and second outer arms and the inner arm extend lengthwise between the proximal body end and the distal body end. The lead also includes an array of electrodes that are configured to apply a neurostimulation therapy within an epidural space of a patient. At least some of the electrodes are positioned along the first and second outer arms. Each of the first and second outer arms includes a resilient member that is biased to flex the corresponding first and second outer arms from a collapsed condition to an expanded condition in a lateral direction away from the inner arm. | 07-17-2014 |
20140180194 | METHOD FOR TREATING NEUROLOGICAL/PSYCHIATRIC DISORDERS WITH STIMULATION TO THE SUBCAUDATE AREA OF THE BRAIN - A method for treating a patient with a neurological or psychiatric disorder, comprising applying stimulation to at least a portion of the patient's subcaudate white matter of the subcaudate area under conditions effective to provide the patient with at least a partial relief from the neurological or psychiatric disorder. The stimulation may be electrical and/or pharmacological. | 06-26-2014 |
20140130349 | MEDICAL LEADS WITH SEGMENTED ELECTRODES AND METHODS OF FABRICATION THEREOF - In one embodiment, a method of fabrication of a stimulation lead comprising a plurality of segmented electrodes for stimulation of tissue of a patient, the method comprises: providing a substrate comprising (i) a substantially cylindrical body and (ii) a plurality of projections extending radially from the cylindrical body; coating the substrate with first conductive material; patterning the first conductive material on the cylindrical body into a plurality of traces, the plurality of traces extending along the cylindrical body and electrically contacting conductive material about the plurality of projections; providing an insulative layer over the traces; coating the insulative layer over the traces with second conductive material; patterning the second conductive material to form at least a plurality of electrode surfaces including a plurality of segmented electrodes, the segmented electrodes being in electrical contact with conductive material on projections of the plurality of projections; and electrically coupling the plurality of traces to conductive wires of a lead body. | 05-15-2014 |
20140005495 | EXTERNAL SYSTEMS FOR DETECTING IMPLANTABLE NEUROSTIMULATION LEADS AND DEVICES, AND METHODS OF USING SAME | 01-02-2014 |
20130338733 | METHOD AND APPARATUS FOR CONTROLLING STIMULATION PULSES DURING THE PROGRAMMING OF AN IMPLANTABLE PULSE GENERATOR - In one embodiment, a method for the controlling of the stimulation pulses being delivered via electrodes to a patient during the programming of a pulse generator using a controller device and selecting of a minimum amplitude that corresponds to the minimum amplitude for which the patient can detect stimulation; selecting an electrode combination defined in the controller device; setting the stimulation amplitude; making a determination of the amplitude for the stimulation pulses is greater than the perception amplitude, and if so, changing the amplitude of the stimulation pulses to be less than or equal to the perception amplitude; and if not or subsequent to the changing of the amplitude, changing the selected one of a plurality of electrode combinations to a different combination. | 12-19-2013 |
20130312258 | STIMULATION LEAD COMPRISING INTERNAL FLEX FILM COMPONENT AND METHOD OF FABRICATION - In one embodiment, a stimulation lead for applying electrical pulses to tissue of a patient, the stimulation lead comprises: a plurality of electrodes on a first end of the lead body; a plurality of terminals on a second end of the lead body; a lead body comprising a flex film component disposed within insulative material, wherein (i) the flex film component comprises a plurality of electrical traces, (ii) the plurality of electrical traces electrically couple the plurality of electrodes with the plurality of terminals, and (iii) the flex film component comprises a plurality of bends along a substantial length of the lead body; wherein the stimulation lead is adapted to elastically elongate under application of stretching forces to the lead body without disconnection of the electrical connections between the plurality of electrodes and the plurality of terminals through the electrical traces of the flex film component. | 11-28-2013 |
20130239403 | HEADER DESIGN FOR IMPLANTABLE PULSE GENERATOR - In one embodiment, an implantable pulse generator for electrically stimulating a patient comprises: a metallic housing enclosing pulse generating circuitry; a header mechanically coupled to the metallic housing, the header adapted to seal terminals of one or more stimulation leads within the header and to provide electrical connections for the terminals; the header comprising an inner compliant component for holding a plurality of electrical connectors, the plurality of electrical connectors electrically coupled to the pulse generating circuitry through feedthrough conductors, wherein the plurality of electrical connectors are held in place in recesses within the compliant inner component, the header further comprising an outer shield component adapted to resist punctures, the outer shield component fitting over at least a portion of the inner compliant component. | 09-19-2013 |
20130238070 | PERIPHERAL NERVE STIMULATION TO TREAT AUDITORY DYSFUNCTION - A system and/or method for treating auditory dysfunction by somatosensory system stimulation. The system and/or method comprises a probe and a device to stimulate the probe. The probe has a stimulation portion implanted in communication with a predetermined peripheral nerve site. The stimulation portion of the probe may be implanted in contact with a peripheral nerve dorsal root ganglia, cranial nerve or dermatome area, for example C2 dermatome area or a trigeminal dermatome area. The stimulation portion may be a laminotomy, paddle, surgical, or multiple electrode lead. The device to stimulate the probe may be implanted subcutaneously or transcutaneously. | 09-12-2013 |
20130231713 | STIMULATION DESIGN FOR NEUROMODULATION - The present application relates to a new stimulation design which can be utilized to treat neurological conditions. The stimulation system produces a burst mode stimulation which alters the neuronal activity of the predetermined site, thereby treating the neurological condition or disorder. The burst stimulus comprises a plurality of groups of spike pulses having a maximum inter-spike interval of 100 milliseconds. The burst stimulus is separated by a substantially quiescent period of time between the plurality of groups of spike pulses. This inter-group interval may comprise a minimum of 5 seconds. | 09-05-2013 |
20130211477 | SYSTEM AND METHOD FOR DEFINING STIMULATION PROGRAMS INCLUDING BURST AND TONIC STIMULATION - In one embodiment, a method for defining a stimulation program for electrical stimulation of a patient, the method comprising: providing a single screen user interface that comprises a first plurality of controls and a second plurality of controls, the first plurality of controls allowing selection of multiple stimulation parameters for a plurality of stimulation sets, the second plurality of controls allowing selection of multiple stimulation parameters defining burst stimulation and tonic stimulation; receiving user input in one or more of the second plurality of controls; and automatically modifying parameters for one or more stimulation sets in response to receiving the user input in one or more of the second plurality of controls and modifying values displayed in one or more controls of the first plurality of controls according to the modified parameters, the modified parameters reflecting a stimulation program that includes an interleaved pattern of burst stimulation and tonic stimulation for delivery to the patient. | 08-15-2013 |
20130184793 | ELECTRICAL STIMULATION SYSTEM AND ASSOCIATED APPARATUS FOR SECURING AN ELECTRICAL STIMULATION LEAD IN POSITION IN A PERSON'S BRAIN - In one aspect, an apparatus is provided for securing an electrical stimulation lead in position in a person's brain. The apparatus includes a flexible disc comprising a substantially radial slot adapted to secure the lead in position within the brain after implantation. The slot is adapted to elastically expand as the lead is inserted into the slot and is also adapted to elastically contract on the lead to secure the lead in position within the brain after implantation. The apparatus further includes a ring adapted to seat within a burr hole formed in the person's skull. The ring comprises a channel adapted to receive and secure the flexible disc. | 07-18-2013 |
20130178913 | METHODS FOR TARGETING DEEP BRAIN SITES TO TREAT MOOD AND/OR ANXIETY DISORDERS - The present invention relates to a method of identifying a target such as within the subgenual area by measuring neuronal activity in response to a stimulus. Once the target is identified, it can be stimulated to treat a neurological disorder, such as a mood disorder or an anxiety disorder. | 07-11-2013 |
20130172956 | METHOD AND APPARATUS FOR CONTROLLING STIMULATION PULSES DURING THE PROGRAMMING OF AN IMPLANTABLE PULSE GENERATOR - In one embodiment, a method for the controlling of the stimulation pulses being delivered via electrodes to a patient during the programming of a pulse generator using a controller device and selecting of a minimum amplitude that corresponds to the minimum amplitude for which the patient can detect stimulation; selecting an electrode combination defined in the controller device; setting the stimulation amplitude; making a determination of the amplitude for the stimulation pulses is greater than the perception amplitude, and if so, changing the amplitude of the stimulation pulses to be less than or equal to the perception amplitude; and if not or subsequent to the changing of the amplitude, changing the selected one of a plurality of electrode combinations to a different combination. | 07-04-2013 |
20130158638 | STIMULATION LEAD AND METHOD OF FABRICATION - In one embodiment, an implantable stimulation lead for delivering electrical stimulation to tissue of a patient, the implantable stimulation lead comprises: a lead body comprising a plurality of wires strands that form a solid helical hollow tube that is maintained by mutual contact pressure of neighboring wire strands, wherein the plurality of wire strands comprise an outer coating of non-conductive material to electrically isolate each of the plurality of wire strands from each other; and a plurality of electrodes with each electrode being electrically coupled to one of the plurality of wire strands. | 06-20-2013 |
20130144353 | Method for treating neurological /psychiatric disorders with stimulation to the subcaudate area of the brain - A method for treating a patient with a neurological or psychiatric disorder, comprising applying stimulation to at least a portion of the patient's subcaudate white matter of the subcaudate area under conditions effective to provide the patient with at least a partial relief from the neurological or psychiatric disorder. The stimulation may be electrical and/or pharmacological. | 06-06-2013 |
20130138191 | IMPLANTABLE ANCHOR WITH LOCKING CAM - There is disclosed various embodiments of an implantable anchor for anchoring a medical lead within a patient. The implantable anchor includes a body having at least one lumen for receiving a medical lead, a cam integrated with the body and rotatable to extend into the lumen for engaging the medical lead and inhibiting the movement of the lead with respect to the anchor. The cam may include a handle for facilitating the rotation of the cam. A needle could be connected to the handle to facilitate the securing of the anchor to a portion of the patient. | 05-30-2013 |
20130138177 | ELECTRICAL STIMULATION SYSTEM AND METHOD FOR STIMULATING TISSUE IN THE BRAIN TO TREAT A NEUROLOGICAL CONDITION - According to one aspect, a stimulation system is provided for electrically stimulating a predetermined site to treat a neurological condition. The system includes an electrical stimulation lead adapted for implantation in communication with a predetermined site, wherein the site is brain tissue site. The stimulation lead includes one or more stimulation electrodes adapted to be positioned in the predetermined site. The system also includes a stimulation source that generates the stimulation pulses for transmission to the one or more stimulation electrodes of the stimulation lead to deliver the stimulation pulses to the predetermined site to treat a neurological disorder or condition. | 05-30-2013 |
20130123894 | IMPLANTABLE PADDLE LEAD COMPRISING STRETCHING ELECTRICAL TRACES AND METHOD OF FABRICATION - In one embodiment, a paddle-style lead for implantation in the epidural space through an insertion tool, the paddle-style lead comprises: a paddle structure that comprises: (i) a frame of rigid material, the frame comprising a spring member adapted to bias the frame to assume a first width and a first length, the frame being adapted to elongate to assume a second width and a second length under application of a compressive force; and (ii) elastic material disposed across an interior surface area defined the frame, wherein a plurality of electrodes and a plurality of electrical traces are provided on the elastic material, wherein the plurality of electrical traces are electrically coupled to a plurality of lead conductors and the plurality of electrodes; wherein the plurality of electrical traces comprises a plurality of alternating curves that elongate when the elastic material is stretched. | 05-16-2013 |
20130116753 | IMPLANTABLE PULSE GENERATOR COMPRISING MRI CURRENT LIMITING WINDINGS IN HEADER STRUCTURE - In one embodiment, a pulse generator for generating electrical stimulation for delivery to a patient, comprises: a hermetically sealed housing containing pulse generating circuitry; a header coupled to the housing for receiving one or more stimulation leads, wherein feedthrough wires are provided to conduct electrical pulses from the pulse generating circuitry to the header; the header comprising a plurality of connectors for electrically connecting to each terminal of the one or more stimulation leads, wherein an inductive winding is disposed around or adjacent to each of the connector structures and is electrically connected between the respective connector structure and a corresponding feedthrough wire to limit MRI induced heating of a respective electrode of the one or more stimulation leads. | 05-09-2013 |
20130096662 | Spinal Cord Stimulation Paddle Lead and Method of Making The Same - In one embodiment, a method of fabricating an implantable stimulation paddle comprises: providing a sheet of conductive material coupled to a first insulative layer; laser removing portions of the conductive material to form a pattern of conductive material, the pattern of conductive material including a plurality of isolated metal traces; providing a second insulative layer over the pattern of conductive material so that the pattern of conductive material is interposed between the first and second insulative layers; and exposing portions of the metal traces to form electrodes on the paddle for delivering electrical stimulation. | 04-18-2013 |
20130096653 | EXTERNAL CHARGING DEVICE FOR CHARGING AN IMPLANTABLE MEDICAL DEVICE AND METHODS OF REGULATING DUTY CYCLE OF AN EXTERNAL CHARGING DEVICE - In one embodiment, an external charging device for recharging an implanted medical device, comprises: a battery for powering the external charging device; a coil for radiating RF power; drive circuitry for driving the coil according to a duty cycle; circuitry for generating a signal that is indicative of an amount of current flowing through the coil; and control circuitry for controlling the drive circuitry, wherein the control circuitry is operable to process the signal from the circuitry for generating to detect when a coil of the implantable medical device temporarily ceases absorbing RF power, the control circuitry modifying the duty cycle in response to detection of the coil of the implantable medical device temporarily ceasing absorbing RF power. | 04-18-2013 |
20130096648 | SYSTEM AND METHOD FOR RESETTING AN IMPLANTABLE MEDICAL DEVICE - In one embodiment, a method, of operating an implantable medical device, comprises: (i) operating reset logic within the implantable medical device that is independently operable from a processor of the implantable medical device after the implantable medical device is implanted within a patient, wherein the processor is adapted for central control of the implantable medical device; (ii) operating a magnetic field sensor in the implantable medical device; (iii) generating digital data using, at least, the magnetic field sensor; (iv) detecting, by the reset logic, a digital key in the digital data; (v) in response to (iv), asserting a reset signal on a pin of the processor by the reset logic; and (vi) conducting reset operations in the processor in response to the reset signal. | 04-18-2013 |
20130041424 | DUODENAL STIMULATION TO INDUCE SATIETY - Methods and devices for creating and/or adding to sensations of satiety to reduce food intake. Methods include electrically stimulating the duodenum which may induce false nerve signals in the duodenal region which are normally indicative of duodenal distension (fullness) and/or the presence of food in the duodenum. The artificially generated signals may be applied in a pattern which mimics at least in part a naturally occurring pattern of duodenal signals generated responsive to eating a meal. Some artificial patterns may be exaggerated relative to the natural patterns, by occurring earlier after ingestion, and/or lasting longer after ingestion, having an exaggerated (higher) frequency response or a faster rate of frequency increase after ingestion. The applied signals may generate nerve signals going to the brain which induce a feeling of satiety. | 02-14-2013 |
20130035730 | IMPLANTABLE PULSE GENERATOR - In one embodiment, there is disclosed a lead locking mechanism for use in a header component of an implantable pulse generator. In certain embodiments, the lead locking mechanism comprises a first locking member positioned to engage a surface of at least two leads; a second locking member positioned to also engage a surface of at least two leads, and a coupling member coupling the first locking member to the second locking member. | 02-07-2013 |
20130030501 | METHOD OF NEUROSTIMULATION OF DISTINCT NEURAL STRUCTURES USING SINGLE PADDLE LEAD TO TREAT MULTIPLE PAIN LOCATIONS AND MULTI-COLUMN, MULTI-ROW PADDLE LEAD FOR SUCH NEUROSTIMULATION - In some embodiments, a paddle lead is implanted within a patient such that the electrodes are positioned within the cervical or thoracic spinal levels. An electrode combination on a first row of electrodes can be determined that is effective for a first pain location with minimal effects on other regions of the body. The first pain location can be addressed by stimulating a first dorsal column fiber due to the relatively fine electrical field resolution achievable by the multiple columns. Then, another electrode combination on a second row of electrodes can be determined for a second pain location with minimal effects on other regions. The second pain location could be addressed by stimulating a second dorsal column fiber. After the determination of the appropriate electrodes for stimulation, the patient's IPG can be programmed to deliver pulses using the first and second rows according to the determined electrode combinations. | 01-31-2013 |
20130018435 | STIMULATION OF THE AMYGDALOHIPPOCAMPAL COMPLEX TO TREAT NEUROLOGICAL CONDITIONS - A system and/or method treating for a neurological disorder by brain region stimulation. The system and/or method comprises a probe and a device to provide stimulation. The probe has a stimulation portion implanted in communication with a predetermined brain region site. The stimulation portion of the probe may be implanted in contact with a predetermined brain region. | 01-17-2013 |
20120286841 | PULSE GENERATOR HAVING AN EFFICIENT FRACTIONAL VOLTAGE CONVERTER AND METHOD OF USE - Disclosed are systems and methods which provide voltage conversion in increments less than integer multiples of a power supply (e.g., battery) voltage. A representative embodiment provides power supply voltage multipliers in a binary ladder distribution to provide a desired number of output voltage steps using a relatively uncomplicated circuit design. By using different sources in various combinations and/or by “stacking” different sources in various ways, the voltage multiplier circuit may be used to provide desired voltages. In order to minimize the number of components used in a voltage converter of an embodiment, a capacitive voltage converter circuit uses one or more storage capacitors in place of pump capacitors in a voltage generation cycle. Also, certain embodiments do not operate to generate an output voltage until the time that voltage is needed. | 11-15-2012 |
20120253440 | DEVICE AND METHOD FOR ENSURING THE PROPER INSERTION OF A LEAD INTO THE HEADER OF AN IMPLANTABLE MEDICAL DEVICE - An implantable medical device that includes a header a cavity or connector bore that extends from an opening at a first end of the header towards a second end of the header. The cavity is configured to receive a first end of a stimulation lead. The header includes a lead insertion indicator positioned at the second end of the cavity for engaging with the stimulation upon complete insertion into the header. The lead insertion indicator is operable between a first operating state and a second operating state, such that when the stimulation lead is not engaged with the lead insertion indicator, the lead insertion indicator operates in the first operating state, and when the stimulation lead properly engages the lead insertion indicator, the lead insertion indicator operates in the second operating state. The lead insertion indicator generates a signal that indicates the corresponding operating state. | 10-04-2012 |
20120232327 | METHOD OF TREATING DEPRESSION, MOOD DISORDERS AND ANXIETY DISORDERS USING NEUROMODULATION - The present application involves a method and a system for using electrical stimulation and/or chemical stimulation to treat depression. More particularly, the method comprises surgically implanting an electrical stimulation lead and/or catheter that is in communication with a predetermined site which is coupled to a signal generator and/or infusion pump that release either an electrical signal and/or a pharmaceutical resulting in stimulation of the predetermined site thereby treating the mood and/or anxiety. | 09-13-2012 |
20120203301 | METHODS USING TRIGEMINAL NERVE STIMULATION TO TREAT NEUROLOGICAL DISEASES - The present description relates to cranial nerve stimulation to treat a neurological disorder. More particularly, and not by way of limitation, the present invention is directed to a system and method for stimulating a cranial nerve to treat a neurological disorder, such as tinnitus or an anxiety disorder. | 08-09-2012 |
20120197371 | CUFF ELECTRODE HAVING TUBULAR BODY WITH CONTROLLED CLOSING FORCE - Nerve cuff electrode including a tubular body having a longitudinal slit and a flap curled over the slit. The tubular body includes a central cathode disposed between two anodes. The region opposite the slit includes a flexible region that determines the flexibility and strength of tube opening and closing. The cuff electrode having a hinge region with a non-linear effective spring constant which can be higher at low cuff openings and lower at large opening to provide an effective yet non-damaging closing force over a wide range of cuff openings. In use, the tube body can be pulled apart using attached suture loops, with one loop and flap pulled under the nerve followed by part of the tubular body. The tubular body can be closed over the nerve and the flap closed over the tube slit. | 08-02-2012 |
20120158092 | STIMULATION SYSTEM AND METHOD TREATING A NEUROLOGICAL DISORDER - According to one aspect, a stimulation system is provided for electrically stimulating a predetermined site to treat a neurological condition. The system includes an electrical stimulation lead adapted for implantation into a subcutaneous area in communication with a predetermined site, wherein the site is neuronal tissue that is associated with C2/C3 dermatome area, or stimulating cervical nerve roots and/or stimulating cranial nerves and/or stimulating any area associated with the occipital area. The stimulation lead includes one or more stimulation electrodes adapted to be positioned in the predetermined site. The system also includes a stimulation source that generates the stimulation pulses for transmission to the one or more stimulation electrodes of the stimulation lead to deliver the stimulation pulses to the predetermined site to treat a neurological disorder or condition. | 06-21-2012 |
20120089203 | ELECTRICAL CONNECTIONS FOR USE IN IMPLANTABLE MEDICAL DEVICES - There is disclosed various embodiments of an electrical connection for electrically connecting implantable medical devices together, such as an electrical connector for connecting an implantable pulse generator to a medical lead. In one embodiment, the electrical connection may include a body having a longitudinal opening defined therein for receiving an electrode of the medical lead and a spring coupled to the body and positioned within the opening, the spring having a curved surface for engaging the surface of the electrode. | 04-12-2012 |
20120078319 | STIMULATION DESIGN FOR NEUROMODULATION - The present application relates to a new stimulation design which can be utilized to treat neurological conditions. The stimulation system produces a burst mode stimulation which alters the neuronal activity of the predetermined site, thereby treating the neurological condition or disorder. The burst stimulus comprises a plurality of groups of spike pulses having a maximum inter-spike interval of 100 milliseconds. The burst stimulus is separated by a substantially quiescent period of time between the plurality of groups of spike pulses. This inter-group interval may comprise a minimum of 5 seconds. | 03-29-2012 |
20120061358 | METHOD OF FABRICATING A STIMULATION LEAD FOR DELIVERING ELECTRICAL PULSES TO TISSUE OF A PATIENT - In one embodiment, a method of fabricating stimulation leads, the method comprises: providing a spool of polymer film; providing a plurality of payout carriers of wires; drawing the polymer film from the spool and the wires from the plurality of payout carriers over a rotating drum, wherein the drum comprises a plurality of grooves over an outer circumferential surface of the drum for directing the wires from the plurality of payout carriers, wherein a distance of each groove from an edge of the drum is varied about the circumference of the drum; bonding the wires to the polymer film while performing the drawing to form an intermediate assembly comprising the polymer film as a carrier with the bonded wires in a repeating pattern along a length of the intermediate assembly. | 03-15-2012 |
20120022611 | METHODS AND APPARATUS FOR EFFECTUATING A LASTING CHANGE IN A NEURAL-FUNCTION OF A PATIENT - The following disclosure describes several methods and apparatus for intracranial electrical stimulation to treat or otherwise effectuate a change in neural-functions of a patient. The methods in accordance with the invention can be used to treat brain damage (e.g., stroke, trauma, etc.), brain disease (e.g., Alzheimer's, Pick's, Parkinson's, etc.), and/or brain disorders (e.g., epilepsy, depression, etc.). The methods in accordance with the invention can also be used to enhance neural-function of normal, healthy brains (e.g., learning, memory, etc.), or to control sensory functions (e.g., pain). | 01-26-2012 |
20120010671 | NOTCHED ELECTRODE FOR ELECTROSTIMULATION LEAD - According to one embodiment, an electrode for use in electrostimulation is provided, where the electrode comprises a notch that operates to substantially eliminate gaseous material from being trapped about the electrode during a molding process of an electrostimulation lead. | 01-12-2012 |
20110319969 | ELECTRIC MODULATION OF SYMPATHETIC NERVOUS SYSTEM - A method is described for the treatment of obesity or other disorders, by electrical activation or inhibition of the sympathetic nervous system. This activation or inhibition can be accomplished by electrically stimulating the greater splanchnic nerve or other portion of the sympathetic nervous system using an implantable pulse generator. This nerve activation can result in reduced food intake and increased energy expenditure. Reduced food intake may occur through a variety of mechanisms that reduce appetite and cause satiety. Increased adrenal gland hormone levels will result in increased energy expenditure. Fat and carbohydrate metabolism, which are also increased by sympathetic nerve activation, will accompany the increased energy expenditure. | 12-29-2011 |
20110273225 | PULSE GENERATOR HAVING AN EFFICIENT FRACTIONAL VOLTAGE CONVERTER AND METHOD OF USE - Disclosed are systems and methods which provide voltage conversion in increments less than integer multiples of a power supply (e.g., battery) voltage. A representative embodiment provides power supply voltage multipliers in a binary ladder distribution to provide a desired number of output voltage steps using a relatively uncomplicated circuit design. By using different sources in various combinations and/or by “stacking” different sources in various ways, the voltage multiplier circuit may be used to provide desired voltages. In order to minimize the number of components used in a voltage converter of an embodiment, a capacitive voltage converter circuit uses one or more storage capacitors in place of pump capacitors in a voltage generation cycle. Also, certain embodiments do not operate to generate an output voltage until the time that voltage is needed. | 11-10-2011 |
20110243423 | SYSTEM AND METHOD FOR INSPECTING ELECTRICAL STIMULATION LEADS - In one embodiment, a method of inspecting a lead body comprising a plurality of wire conductors helically wound in groups separated by respective gaps, the system comprises: providing a lead body comprising a plurality of wire conductors, helically wound in groups separated by respective gaps, in transparent insulative material, in a channel of a fixture; providing a sensor module; scanning the sensor module along a substantial length of the lead body to obtain image, interferometric, or other data of the lead body; electronically processing the data to calculate respective distances from given turns within a group of the wire conductors from an other sheath of the lead body; determining whether the calculated respective distances correspond to expected values within defined tolerances; and generating an inspection report for the lead body based on the determining. | 10-06-2011 |
20110208265 | MULTI-PROGRAMMABLE TRIAL STIMULATOR - Disclosed are systems and methods which provide trial stimulators suited for use interoperatively and during patient trial. Trial stimulator embodiments provide a patient interface and/or clinician interface which appears and functions substantially the same as an interface of a pulse generator controller which will be used after a trial period. A compliance monitor feature may be provided to facilitate verifying the proper use of the trial stimulator during a trial period. A diagnostic feature may be provided to facilitate verifying proper operation of various aspects of a trial stimulator, such as electrode impedance analysis. Trial stimulators of embodiments provide stimulation to a plurality of tissues and/or areas of the body, such as spinal cord stimulation, deep brain stimulation, etcetera. Embodiments provide for multi-electrode stimulation and multi-stimulation programs. Embodiments are configured to provide active discharge of stimulation pulses as well as to utilize constant current sources in providing the stimulation pulses. | 08-25-2011 |
20110178568 | ELECTRIC MODULATION OF SYMPATHETIC NERVOUS SYSTEM - A method is described for the treatment of obesity or other disorders, by electrical activation or inhibition of the sympathetic nervous system. This activation or inhibition can be accomplished by electrically stimulating the greater splanchnic nerve or other portion of the sympathetic nervous system using an implantable pulse generator. This nerve activation can result in reduced food intake and increased energy expenditure. Reduced food intake may occur through a variety of mechanisms that reduce appetite and cause satiety. Increased adrenal gland hormone levels will result in increased energy expenditure. Fat and carbohydrate metabolism, which are also increased by sympathetic nerve activation, will accompany the increased energy expenditure. | 07-21-2011 |
20110167631 | METHOD FOR PRODUCING A MULTIELECTRODE LEAD - A wire wrapping device that includes a turntable assembly that is made up of a turntable and a driver adapted to rotate the turntable. Also, a set of payout carriers are mounted on the turntable, each payout carrier adapted to let out wire to be wrapped. A driver is adapted to turn each payout carrier relative to the turn table, the driver being user adjustable to turn each payout carrier by a selectable amount, per each complete rotation of the turntable. | 07-14-2011 |
20110098778 | STIMULATION SYSTEM AND METHOD TREATING A NEUROLOGICAL DISORDER - According to one aspect, a method of treating a patient by electrically stimulating a predetermined site to treat a neurological condition. The method includes implanting a lead into subcutaneous tissue of the C | 04-28-2011 |
20100298919 | WINGED ELECTRODE BODY FOR SPINAL CORD STIMULATION - An implantable stimulation system including epidural lead for spinal cord stimulation that includes a paddle having a curved proximal end and lateral winged tips and an array of electrodes coupled to conductors within a lead body. The conductors couple to a pulse generator or other stimulation device. The curved and winged paddle provides more complete electrical stimulation coverage to targeted human tissue by minimizing the potential gap between electrodes and targeted fibers. | 11-25-2010 |
20100269339 | METHOD OF FABRICATING STIMULATION LEAD BY FUSING CONNECTOR SEGMENT BETWEEN LEAD BODY AND ELECTRODE PORTION OF THE LEAD - In one embodiment, a process, for fabricating a medical lead comprises: providing a splicing tube having a plurality of angularly spaced longitudinal grooves; placing a first plurality of conductors within the plurality of angularly spaced grooves defined on an exterior surface of the splicing tube; placing a second plurality of conductors within the plurality of angularly spaced grooves and adjacent to the first plurality of conductors such that a portion of the distal ends overlap a portion of the proximal ends; positioning conductive filler material adjacent to the overlapped portions of the distal and proximal ends; electrically coupling the proximal ends of the first plurality of electrodes to respective proximal ends of the second plurality of electrodes; molding insulative material about at least the electrode assembly and the splicing tube; and fusing the splicing tube with the insulative material from the molding and the lead body. | 10-28-2010 |
20100269338 | MEDICAL LEADS WITH SEGMENTED ELECTRODES AND METHODS OF FABRICATION THEREOF - In one embodiment, a process, for fabricating a medical lead for stimulation of tissue of a patient, comprises: providing a plurality of wires; increasing an exterior surface area of each wire of the plurality of wires; arranging the plurality of wires angularly around a longitudinal axis; extruding polymer material of the plurality of wires; forming a lead body with a proximal end and a distal end after performing the extruding; and forming a plurality of terminals at a proximal end of the lead body; forming a plurality of segmented electrodes at a distal end of the lead body. | 10-28-2010 |
20100269337 | MEDICAL LEADS WITH SEGMENTED ELECTRODES AND METHODS OF FABRICATION THEREOF - In one embodiment, a process, for fabricating a medical lead for stimulation of tissue of a patient, comprises: forming a plurality of electrode assemblies wherein each electrode assembly of the plurality of electrode assemblies comprises a respective plurality of segmented electrodes angularly separated by ribs formed in one or more segments of thermoplastic tape; electrically coupling a conductor to each segmented electrode; molding polymer material around each segmented electrode of the plurality of segmented electrodes to interlock each segmented electrode with polymer material to form a distal end of the medical lead; and fusing the one or more segments of thermoplastic tape of each of the plurality of electrode assemblies with the polymer material. | 10-28-2010 |
20100262205 | STIMULATION DESIGN FOR NEUROMODULATION - The present application relates to a new stimulation design which can be utilized to treat neurological conditions. The stimulation system produces a burst mode stimulation which alters the neuronal activity of the predetermined site, thereby treating the neurological condition or disorder. The burst stimulus comprises a plurality of groups of spike pulses having a maximum inter-spike interval of 100 milliseconds. The burst stimulus is separated by a substantially quiescent period of time between the plurality of groups of spike pulses. This inter-group interval may comprise a minimum of 5 seconds. | 10-14-2010 |
20100241189 | Nerve Stimulation For Treatment of Obesity, Metabolic Syndrome, and Type 2 Diabetes - A tissue modulation device, for treating at least one of obesity, metabolic syndrome, and Type 2 diabetes in a patient, is described. In some embodiments, the device includes a storage module having computer-readable instructions for delivering an electrical stimulation pattern to a splanchnic nerve of the patient. The stimulation pattern includes at least one on-time. The on-time includes at least one of a suprathreshold period and a subthreshold period. The splanchnic nerve is selected from the group consisting of the greater splanchnic nerve, the lesser splanchnic nerve, and the least splanchnic nerve. The pattern is effective to ameliorate at least one attendant condition of obesity, metabolic syndrome, and Type 2 diabetes in the patient. The attendant condition includes dyslipidemia, hypertension, hyperinsulinemia, hyperglycemia, and/or insulin resistance. | 09-23-2010 |
20100204749 | STIMULATION SYSTEM AND METHOD TREATING A NEUROLOGICAL DISORDER - According to one aspect, a stimulation system is provided for electrically stimulating a predetermined site to treat a neurological condition. The system includes an electrical stimulation lead adapted for implantation into a subcutaneous area in communication with a predetermined site, wherein the site is neuronal tissue that is associated with C2/C3 dermatome area, or stimulating cervical nerve roots and/or stimulating cranial nerves and/or stimulating any area associated with the occipital area. The stimulation lead includes one or more stimulation electrodes adapted to be positioned in the predetermined site. The system also includes a stimulation source that generates the stimulation pulses for transmission to the one or more stimulation electrodes of the stimulation lead to deliver the stimulation pulses to the predetermined site to treat a neurological disorder or condition. | 08-12-2010 |
20100193065 | METHOD FOR PRODUCING A MULTIELECTRODE LEAD - A wire wrapping device that includes a turntable assembly that is made up of a turntable and a driver adapted to rotate the turntable. Also, a set of payout carriers are mounted on the turntable, each payout carrier adapted to let out wire to be wrapped. A driver is adapted to turn each payout carrier relative to the turn table, the driver being user adjustable to turn each payout carrier by a selectable amount, per each complete rotation of the turntable. | 08-05-2010 |
20100145428 | METHOD OF USING SPINAL CORD STIMULATION TO TREAT NEUROLOGICAL DISORDERS OR CONDITIONS - The present invention involves methods and systems for using electrical stimulation to treat neurological disorders. More particularly, the method comprises surgically implanting an electrical stimulation lead that is in communication with spinal nervous tissue associated with a first, second, or third cervical vertebral segment to result in spinal nervous tissue stimulation, thus treating a wide variety of neurological disorders. | 06-10-2010 |
20100145427 | METHODS AND APPARATUS FOR EFFECTUATING A LASTING CHANGE IN A NEURAL-FUNCTION OF A PATIENT - The following disclosure describes several methods and apparatus for intracranial electrical stimulation to treat or otherwise effectuate a change in neural-functions of a patient. Certain embodiments of methods in accordance with the invention electrically stimulate the brain at a stimulation site where neuroplasticity is occurring or is expected to occur. The stimulation site may be different than the region in the brain where neural activity is typically present to perform the particular neural function according to the functional organization of the brain. In one embodiment in which neuroplasticity related to the neural-function occurs in the brain, the method can include identifying the location where such neuroplasticity is present or expected to occur. In an alternative embodiment in which neuroplasticity is not occurring in the brain, an alternative aspect is to induce neuroplasticity at a stimulation site where it is expected to occur. Several embodiments of these methods that are expected to produce a lasting effect on the intended neural activity at the stimulation site use electrical pulses that increase the resting membrane potential of neurons at the stimulation site to a subthreshold level. | 06-10-2010 |
20100141676 | SYSTEM FOR REGIONAL DATA ASSOCIATION AND PRESENTATION AND METHOD FOR THE SAME - A database methodology that concerns the mapping of any arbitrary object into a plurality of regions, enabling the assignment of multiple region-specific attributes thereto and facilitating the concurrent, graphical presentation of any assigned attributes. Attribute storage, manipulation, and presentation are driven by the individual regions and characteristics of the object. | 06-10-2010 |
20100131034 | SYSTEMS AND METHODS FOR AUTOMATICALLY OPTIMIZING STIMULUS PARAMETERS AND ELECTRODE CONFIGURATIONS FOR NEUROSTIMULATORS - Test procedures for determining a neural stimulation threshold of a patient. In one embodiment, the procedure includes applying a test stimulation signal to the patient and monitoring the patient for a response to the test stimulation signal. The procedure can further include determining a first neural stimulation threshold and calculating a second neural stimulation threshold. The first neural stimulation threshold corresponds to the lowest intensity test stimulation signal that evokes a patient response. The second neural stimulation threshold corresponds to a treatment stimulation signal directed toward affecting a neural activity within the patient. | 05-27-2010 |
20100131030 | METHODS AND APPARATUS FOR EFFECTUATING A CHANGE IN A NEURAL-FUNCTION OF A PATIENT - The present disclosure is directed generally to methods and apparatus for effectuating a change in a neural function of a patient. A method in accordance with a particular embodiment includes implanting an electrode at a cortical stimulation site selected to promote recovery of the affected neural-function, with the cortical stimulation site being at least proximate to the cortex. The method can further include estimating a threshold for the specific patient at which an electrical signal delivered via the implanted electrode directly triggers a neural reaction associated with the stimulation site in response to the delivered electrical signal, and electrically stimulating the cortical stimulation site by Passing an electrical current through the electrode. | 05-27-2010 |
20100114193 | METHOD OF TREATING DEPRESSION, MOOD DISORDERS AND ANXIETY DISORDERS USING NEUROMODULATION - The present application involves a method and a system for using electrical stimulation and/or chemical stimulation to treat depression. More particularly, the method comprises surgically implanting an electrical stimulation lead and/or catheter that is in communication with a predetermined site which is coupled to a signal generator and/or infusion pump that release either an electrical signal and/or a pharmaceutical resulting in stimulation of the predetermined site thereby treating the mood and/or anxiety. | 05-06-2010 |
20100057160 | Stimulation of the amygdalohippocampal complex to treat neurological conditions - A system and/or method treating for a neurological disorder by brain region stimulation. The system and/or method comprises a probe and a device to provide stimulation. The probe has a stimulation portion implanted in communication with a predetermined brain region site. The stimulation portion of the probe may be implanted in contact with a predetermined brain region. | 03-04-2010 |
20100004637 | System and method for implantation of devices having unknown biocompatible materials - There is disclosed a system and method for allowing use within a body of devices having material not known for its biocompatibility with the body. In one embodiment, a magnetically controlled solenoid/valve is used where portions of the valve are directly in contact with compositions that are to be delivered to a target site. Advantage is taken of an existing solenoid/valve having chromium alloy parts by coating the portions of the valve that contact the deliverable composition with a known biocompatible material having good wear resistance. In one embodiment, titanium nitride (TiN) is used as the coating material. | 01-07-2010 |
20090292344 | METHODS AND SYSTEMS FOR INTRACRANIAL NEUROSTIMULATION AND/OR SENSING - Methods and systems for intracranial neurostimulation and/or sensing are disclosed. An intracranial signal transmission system in accordance with an embodiment of the invention includes a generally electrically insulating body having a head portion configured to be positioned at least proximate to an outer surface of a patient's skull, and a shaft portion configured to extend into an aperture in the patient's skull. The system can further include at least one electrical contact portion integrated with the support body. The at least one electrical contact portion can be positioned to transfer electrical signals to, from, or both to and from the patient's brain via an aperture in the patient's skull. | 11-26-2009 |
20090143845 | NOTCHED ELECTRODE FOR ELECTROSTIMULATION LEAD - According to one embodiment, an electrode for use in electrostimulation is provided, where the electrode comprises a notch that operates to substantially eliminate gaseous material from being trapped about the electrode during a molding process of an electrostimulation lead. | 06-04-2009 |
20090024187 | MULIT-PROGRAMMABLE TRIAL STIMULATOR - Disclosed are systems and methods which provide trial stimulators suited for use interoperatively and during patient trial. Trial stimulator embodiments provide a patient interface and/or clinician interface which appears and functions substantially the same as an interface of a pulse generator controller which will be used after a trial period. A compliance monitor feature may be provided to facilitate verifying the proper use of the trial stimulator during a trial period. A diagnostic feature may be provided to facilitate verifying proper operation of various aspects of a trial stimulator, such as electrode impedance analysis. Trial stimulators of embodiments provide stimulation to a plurality of tissues and/or areas of the body, such as spinal cord stimulation, deep brain stimulation, etcetera. Embodiments provide for multi-electrode stimulation and multi-stimulation programs. Embodiments are configured to provide active discharge of stimulation pulses as well as to utilize constant current sources in providing the stimulation pulses. | 01-22-2009 |
20080297527 | SYSTEM FOR REGIONAL DATA ASSOCIATION AND PRESENTATION AND METHOD FOR THE SAME - A database methodology that concerns the mapping of any arbitrary object into a plurality of regions, enabling the assignment of multiple region-specific attributes thereto and facilitating the concurrent, graphical presentation of any assigned attributes. Attribute storage, manipulation, and presentation are driven by the individual regions and characteristics of the object. | 12-04-2008 |